Assessing liver fat levels in HIV/AIDS patients on different medications

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the prevalence and severity of nonalcoholic fatty liver disease (NAFLD) among patients living with HIV/AIDS, particularly focusing on those treated with integrase inhibitors (INSTIs) versus non-nucleoside reverse transcriptase inhibitors (NNRTIs). By utilizing various imaging techniques such as ultrasonography and elastography, the study seeks to identify patients at risk of severe liver conditions like nonalcoholic steatohepatitis (NASH) and fibrosis. The research will involve a cross-sectional analysis of newly treated or treated AIDS patients who are compliant with their medication and follow-up visits. The findings could provide insights into the impact of different antiretroviral therapies on liver health in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Newly treated or treated AIDS patients;
* Regular follow-up visits to the hospital, medication compliance is good;
* Patients or their family members were willing to participate in the study by understanding the study plan and providing written informed consent.

Exclusion Criteria:

* Unable to complete the position requirements of ultrasonic examination (lying flat) due to mobility difficulties;
* Patients have poor compliance and cannot follow up regularly or take medicine on time;
* Patients or family members cannot understand the conditions and objectives of the study;
* Other conditions considered unsuitable for inclusion by the investigator.

Where it's running

• Chinese Academy of Medical Sciences Peking Union Medical College Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: WEI Lyu — Department of Infectious Diseases, PekingUMCH
• Study coordinator: Qing Zhang
• Email: zhangqingpumch@163.com
• Phone: 13207572893

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Imaging endometriosis with a special PET tracer in adult women

  This study tests whether a PET/CT scan using [18F]AlF-FAPI-74 can help detect endometriosis lesions in women who are planning laparoscopy.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07876648

• Inhaled mosliciguat for pulmonary hypertension in interstitial lung disease (PH-ILD) patients

  This study tests inhaled mosliciguat versus placebo in people with PH-ILD to see if it helps with their condition.

  Recruiting at 3 sites Phase 3 Pulmovant, Inc. · Kissimmee, Florida and 2 other locations · NCT07816185

• Peer-led Dynamic Choice HIV Prevention for Women

  This trial tests a peer-led HIV prevention approach to see if it helps women at higher risk in Uganda better prevent HIV than standard care.

  Recruiting University of California, San Francisco · Kampala · NCT07787988

• Tesamorelin to reduce liver fat in adults with fatty liver disease

  This trial tests whether a daily self‑injection of tesamorelin can lower liver fat over 52 weeks in adults with fatty liver disease.

  Recruiting Phase 2 Hudson Biotech · Shenzhen, Guangdong · NCT07481734

• Copper supplementation for people with cirrhosis

  This trial will try giving copper supplements to adults with cirrhosis who have low copper levels or signs of copper deficiency to see if liver-related health improves.

  Recruiting University of Washington · Seattle, Washington · NCT07471542

• Western Sweden Systemic Sclerosis Project

  This project will collect blood, skin and DNA samples from people with systemic sclerosis in Western Sweden to try to find genes, proteins, and immune changes linked to how the disease starts and gets worse.

  Recruiting Sahlgrenska University Hospital · Gothenburg, Sweden · NCT07345052

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.