NIH-funded research R01 grant

Hearing changes in people with HIV and in people without HIV in Tanzania

Official title: Advancing and applying peripheral and central auditory findings in HIV/AIDS.

Funded at Dartmouth College · NIH-11575474 · Data updated 2026-11-12

This project follows people living with HIV and similar individuals in Tanzania to see how hearing and brain function relate over time and whether hearing tests can help predict cognitive changes.

More AIDS research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDartmouth College
NIH-funded
Lab location1 site (Hanover, United States)
Project startJuly 1, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$255,047
NIH project number3R01DC020135-05S1
Project IDNIH-11575474 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV and HIV-uninfected controls who have been part of the Ubongo Sikivu cohort and can participate in hearing and neurocognitive assessments.

Less likely to help

Individuals without HIV who are not part of the study or who cannot complete hearing or cognitive testing may not benefit.

What this research studies

The study builds on a long-running group in Tanzania that has regular hearing tests and in-depth brain function assessments. It uses those data to explore how HIV, its treatment, age, and long-term antiviral medications affect both peripheral and central hearing, and how central auditory tests relate to thinking skills. By tracking participants over time, researchers aim to see if changes in hearing tests can forecast future cognitive changes in people living with HIV. The work leverages existing cohorts and adds analyses that connect hearing measurements to neurocognitive performance. The findings could guide early identification of cognitive risks and inform hearing-related care for people living with HIV.

Why it matters

Potential benefit: If successful, the project could help clinicians predict and monitor cognitive decline in people with HIV using hearing-based markers.

How similar studies have gone: Prior work has shown a link between central auditory test results and cognitive performance in people with HIV, supporting this approach's potential.

Where this research is happening

  • Dartmouth College
    Hanover, United States
    Active

Researchers

  • Principal investigator: Buckey, Jay C — Dartmouth College
  • Study coordinator: Buckey, Jay C

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.