Hearing changes in people with HIV and in people without HIV in Tanzania
Official title: Advancing and applying peripheral and central auditory findings in HIV/AIDS.
Funded at Dartmouth College · NIH-11575474 · Data updated 2026-11-12
This project follows people living with HIV and similar individuals in Tanzania to see how hearing and brain function relate over time and whether hearing tests can help predict cognitive changes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $255,047 |
| NIH project number | 3R01DC020135-05S1 |
| Project ID | NIH-11575474 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV and HIV-uninfected controls who have been part of the Ubongo Sikivu cohort and can participate in hearing and neurocognitive assessments.
✕Less likely to help
Individuals without HIV who are not part of the study or who cannot complete hearing or cognitive testing may not benefit.
What this research studies
The study builds on a long-running group in Tanzania that has regular hearing tests and in-depth brain function assessments. It uses those data to explore how HIV, its treatment, age, and long-term antiviral medications affect both peripheral and central hearing, and how central auditory tests relate to thinking skills. By tracking participants over time, researchers aim to see if changes in hearing tests can forecast future cognitive changes in people living with HIV. The work leverages existing cohorts and adds analyses that connect hearing measurements to neurocognitive performance. The findings could guide early identification of cognitive risks and inform hearing-related care for people living with HIV.
Why it matters
Potential benefit: If successful, the project could help clinicians predict and monitor cognitive decline in people with HIV using hearing-based markers.
How similar studies have gone: Prior work has shown a link between central auditory test results and cognitive performance in people with HIV, supporting this approach's potential.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Buckey, Jay C — Dartmouth College
- Study coordinator: Buckey, Jay C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.