NIH-funded research U01 cooperative agreement

Tailored smartphone messages to help Cambodians with HIV quit smoking

Official title: Ending Tobacco Use through Interactive Tailored Messaging for Cambodian People Living with HIV/AIDS (EndIT)

Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11401633 · Data updated 2026-11-12

A smartphone program that sends personalized messages and offers medications to help adults living with HIV in Cambodia stop smoking.

More AIDS research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionH. Lee Moffitt Cancer Ctr & Res Inst
NIH-funded
Lab location1 site (Tampa, United States)
Project startSeptember 17, 2021
Project endAugust 31, 2027
Funding year2025
Award (this year)$189,132
NIH project number3U01CA261598-05S1
Project IDNIH-11401633 on NIH RePORTER

Who could benefit from this research

Could help

Adults (21 years and older) living with HIV in Cambodia who currently smoke cigarettes and are receiving antiretroviral therapy are the ideal candidates.

Less likely to help

People who do not smoke, are younger than 21, are not located in Cambodia, lack smartphone access, or decline medications or messaging support are unlikely to benefit from participation.

What this research studies

You would receive interactive, tailored messages on your smartphone designed to support quitting, along with pharmacologic treatment when appropriate. The program combines behavioral messaging and medication and is delivered automatically through an mHealth platform that the team already piloted in Cambodia. People will be randomly assigned to the messaging-plus-medication approach or a comparison group so researchers can see which helps more people quit. Study staff will follow participants over time while they continue their HIV care to track smoking and health outcomes.

Why it matters

Potential benefit: If successful, this approach could help more people with HIV in Cambodia quit smoking and improve their long-term health and survival.

How similar studies have gone: Similar smartphone and text-message programs have shown promise for helping smokers quit in higher-income countries and a small Cambodian pilot demonstrated feasibility, but larger trials are needed to confirm effectiveness.

Where this research is happening

  • H. Lee Moffitt Cancer Ctr & Res Inst
    Tampa, United States
    Active

Researchers

  • Principal investigator: Vidrine, Damon J. — H. Lee Moffitt Cancer Ctr & Res Inst
  • Study coordinator: Vidrine, Damon J.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.