Improving HIV care engagement for Latinos
Official title: ADELANTE: A Randomized Controlled Trial of an Intervention to Improve Engagement in Care for Latinos With HIV
Run by Massachusetts General Hospital · NCT06274632 · Data updated 2026-11-12
This study is testing a new program called ADELANTE to see if it helps Latinos with HIV better manage their health and achieve lower viral levels compared to just getting reminder phone calls.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 2 sites (Miami, Florida and 1 other locations) |
| Status | Recruiting |
| Started | May 22, 2024 |
| Main results expected | February 28, 2027 |
| Study ends | February 28, 2027 |
| Registry record updated | September 22, 2026 |
| Trial ID | NCT06274632 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Latino adults aged 18 and older who have been on HIV treatment for at least six months and show evidence of viral non-suppression.
✕Probably not a fit
Patients who lack the capacity to consent or are currently participating in another HIV intervention study may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of the ADELANTE intervention, a community health worker-delivered program, in improving viral suppression among Latinos with HIV. Participants will be randomly assigned to receive either ADELANTE, which includes five sessions focused on problem-solving and self-management skills, or an enhanced care condition that consists of reminder phone calls. The study will measure outcomes such as rates of viral suppression and emergency room visits over a 12-month period. Participants will be recruited from clinics in areas with high HIV incidence and will be compensated for their involvement.
Why it matters
Potential benefit: If successful, this intervention could lead to improved health outcomes and better management of HIV for Latino patients.
How similar studies have gone: Other studies have shown promise in using community health workers to improve health outcomes in similar populations, indicating a potential for success with this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Self-identify as Latino/Latina/Latinx/Hispanic; adults 18 years and over; with HIV infection confirmed by standard laboratory results available in the medical record; 3 or more months from initial entry into care with a medical provider who can prescribe HIV antiretroviral treatment; receiving HIV primary care at Jackson Memorial Hospital or Thomas Street at Quentin Mease Health Center/Harris Health System, University of Miami's Continuity Clinic, or another HIV primary care clinic in Miami/Dade County; and medical record evidence with last viral load (VL) indicating viral non-suppression (HIV RNA ≥200 cpm) within 12 months prior to assessment of eligibility, as it is typical for providers to obtain laboratories prior to a clinic visit in preparation for counseling. Exclusion Criteria: * Lacks capacity to consent (measured by a validated screener), plans to move out of the county in the next 6 months, or currently participating in an HIV intervention study with ongoing follow-up.
Where it's running
-
University of Miami
Miami, Florida, United States Recruiting -
Baylor College of Medicine
Houston, Texas, United States Recruiting
Study contacts
- Study coordinator: Julie H Levison, MD
- Email: jlevison@mgb.org
- Phone: 617-724-4698
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.