Improving HIV care engagement for Latinos

ADELANTE: A Randomized Controlled Trial of an Intervention to Improve Engagement in Care for Latinos With HIV

NA · Massachusetts General Hospital · NCT06274632

This study is testing a new program called ADELANTE to see if it helps Latinos with HIV better manage their health and achieve lower viral levels compared to just getting reminder phone calls.

Quick facts

PhaseNA
Study typeInterventional
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorMassachusetts General Hospital (other)
Locations2 sites (Miami, Florida and 1 other locations)
Trial IDNCT06274632 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of the ADELANTE intervention, a community health worker-delivered program, in improving viral suppression among Latinos with HIV. Participants will be randomly assigned to receive either ADELANTE, which includes five sessions focused on problem-solving and self-management skills, or an enhanced care condition that consists of reminder phone calls. The study will measure outcomes such as rates of viral suppression and emergency room visits over a 12-month period. Participants will be recruited from clinics in areas with high HIV incidence and will be compensated for their involvement.

Who should consider this trial

Good fit: Ideal candidates are Latino adults aged 18 and older who have been on HIV treatment for at least six months and show evidence of viral non-suppression.

Not a fit: Patients who lack the capacity to consent or are currently participating in another HIV intervention study may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could lead to improved health outcomes and better management of HIV for Latino patients.

How similar studies have performed: Other studies have shown promise in using community health workers to improve health outcomes in similar populations, indicating a potential for success with this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self-identify as Latino/Latina/Latinx/Hispanic; adults 18 years and over; with HIV infection confirmed by standard laboratory results available in the medical record; 3 or more months from initial entry into care with a medical provider who can prescribe HIV antiretroviral treatment; receiving HIV primary care at Jackson Memorial Hospital or Thomas Street at Quentin Mease Health Center/Harris Health System; and medical record evidence with last viral load (VL) indicating viral non-suppression (HIV RNA ≥200 cpm) within 12 months prior to assessment of eligibility, as it is typical for providers to obtain laboratories prior to a clinic visit in preparation for counseling.

Exclusion Criteria:

* Lacks capacity to consent (measured by a validated screener), plans to move out of the county in the next 6 months, or currently participating in an HIV intervention study with ongoing follow-up.

Where this trial is running

Miami, Florida and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: HIV/AIDS, Latino, Hispanic, health outcomes, community health worker

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.