Mobile intervention for HIV prevention in young men who have sex with men

MyPEEPS Mobile Plus

Not applicable Interventional Columbia University · NCT06741618

This study is testing a mobile program that helps young men who have sex with men learn about and access HIV prevention methods, like PrEP, to see if it can reduce their risk of getting HIV.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment500 (estimated)
Ages16 Years to 25 Years
SexMale
SponsorColumbia University Academic / other
Locations1 site (New York, New York)
Trial IDNCT06741618 on ClinicalTrials.gov

What this trial studies

MyPEEPS Mobile Plus is a multi-level intervention designed to enhance HIV prevention outcomes among young men who have sex with men (YMSM) by utilizing mobile technology to deliver tailored HIV prevention information. This intervention combines the MyPEEPS Mobile platform with PrEP E-Peer Navigation to address barriers to PrEP initiation and adherence. The study aims to assess the efficacy of this approach in promoting PrEP uptake and reducing HIV-related risk behaviors through a randomized controlled trial. By leveraging digital tools and peer support, the intervention seeks to reach a diverse population of YMSM effectively.

Who should consider this trial

Good fit: Ideal candidates for this study are HIV-negative young men aged 17-25 who identify as male, non-binary, or genderqueer and have engaged in condomless anal sex with a male partner in the past year.

Not a fit: Patients who are HIV-positive, currently using PrEP, or unable to provide informed consent due to cognitive impairment or substance influence may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly increase PrEP uptake and adherence among high-risk young MSM, leading to reduced HIV transmission rates.

How similar studies have performed: Other studies have shown success with similar digital and peer navigation approaches in improving HIV prevention outcomes among at-risk populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 16-25 years of age
* identify as male, non-binary, or genderqueer
* male sex assigned at birth
* understand and read English
* own a smartphone
* report condomless anal sex with a male in the past year
* HIV-negative (OraQuick verified)

Exclusion Criteria:

* HIV Positive
* If study staff determine participant unable to consent due to obvious and severe cognitive impairment or under the influence of drugs or alcohol
* currently report consistent use of PrEP

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIV/AIDSPrEPcare navigation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.