Observational research on chronic diseases and healthcare analytics

OPERA Longitudinal Observational Database in the Study of Chronic Diseases, Treatments and Outcomes

Observational Epividian · NCT03813862

This study looks at health records to see how well different treatments work for chronic diseases like HIV and hepatitis, aiming to improve patient care and support.

Quick facts

Study typeObservational
Enrollment2000000 (estimated)
Ages0 Years and up
SexAll
SponsorEpividian Industry-sponsored
Locations1 site (Durham, North Carolina)
Trial IDNCT03813862 on ClinicalTrials.gov

What this trial studies

This study utilizes the OPERA longitudinal database, which collects de-identified electronic health record (EHR) data from various clinical practices to research chronic diseases such as HIV, HCV, and HBV. The aim is to enhance clinical decision support systems and improve patient engagement through sophisticated healthcare analytics. By analyzing real-world data, the study seeks to provide insights into treatment outcomes and quality measures for chronic disease management. The findings will be disseminated through scientific conferences and peer-reviewed journals to inform healthcare practices.

Who should consider this trial

Good fit: Ideal candidates for this study are patients receiving treatment for chronic diseases documented in participating practices' EHR systems.

Not a fit: Patients who opt out of the OPERA program will not benefit from this study.

Why it matters

Potential benefit: If successful, this research could lead to improved management and treatment outcomes for patients with chronic diseases.

How similar studies have performed: Other studies utilizing observational data and EHR systems have shown success in improving patient outcomes and healthcare quality, indicating a promising approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who are treated in the practices who enroll and participate in the study
* Patients whose treatment is documented in the practice's electronic health record system

Exclusion Criteria:

* Patients who opt out of OPERA

Where this trial is running

Durham, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic DiseaseHIV/AIDSLiver DiseasesInflammatory Bowel DiseasesCardiovascular DiseasesRheumatic DiseasesNeurodegenerative Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.