Observational research on chronic diseases and healthcare analytics
Official title: OPERA Longitudinal Observational Database in the Study of Chronic Diseases, Treatments and Outcomes
Run by Epividian · NCT03813862 · Data updated 2026-11-12
This study looks at health records to see how well different treatments work for chronic diseases like HIV and hepatitis, aiming to improve patient care and support.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 0 Years and up |
| Sex | All |
| Enrollment | 2000000 (estimated) |
| Sponsor | Epividian Industry-sponsored |
| Locations | 1 site (Durham, North Carolina) |
| Status | Recruiting |
| Started | December 1, 2013 |
| Main results expected | November 2035 |
| Study ends | November 2035 |
| Registry record updated | September 11, 2026 |
| Trial ID | NCT03813862 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients receiving treatment for chronic diseases documented in participating practices' EHR systems.
✕Probably not a fit
Patients who opt out of the OPERA program will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study utilizes the OPERA longitudinal database, which collects de-identified electronic health record (EHR) data from various clinical practices to research chronic diseases such as HIV, HCV, and HBV. The aim is to enhance clinical decision support systems and improve patient engagement through sophisticated healthcare analytics. By analyzing real-world data, the study seeks to provide insights into treatment outcomes and quality measures for chronic disease management. The findings will be disseminated through scientific conferences and peer-reviewed journals to inform healthcare practices.
Why it matters
Potential benefit: If successful, this research could lead to improved management and treatment outcomes for patients with chronic diseases.
How similar studies have gone: Other studies utilizing observational data and EHR systems have shown success in improving patient outcomes and healthcare quality, indicating a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who are treated in the practices who enroll and participate in the study * Patients whose treatment is documented in the practice's electronic health record system Exclusion Criteria: * Patients who opt out of OPERA
Where it's running
-
Epividian
Durham, North Carolina, United States Recruiting
Study contacts
- Study coordinator: Gregory Fusco, MD
- Email: gregory.fusco@epividian.com
- Phone: 224-632-1862
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.