Hearing and brain function in people with HIV in Tanzania
Official title: Advancing and applying peripheral and central auditory findings in HIV/AIDS.
Funded at Dartmouth College · NIH-11389566 · Data updated 2026-11-12
This project studies how hearing and brain function change over time in people with HIV and similar people without HIV in Tanzania, to see if ear tests can foretell cognitive decline.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $398,766 |
| NIH project number | 5R01DC020135-05 |
| Project ID | NIH-11389566 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with HIV and HIV-uninfected controls in the Ubongo Sikivu cohort who have undergone long-term hearing and cognitive assessments.
✕Less likely to help
Individuals without HIV or those not in the cohort may not directly benefit from this study.
What this research studies
Researchers are following a long-running group in Tanzania that includes people living with HIV and HIV-negative controls, with regular checks of hearing and brain-related functions. The study uses both ear-specific and central brain tests, along with neurocognitive assessments, to understand how HIV and its treatment affect the auditory system and cognition over time. The team will look at whether changes in central auditory tests can predict future cognitive problems and whether long-term antiretroviral therapy influences these relationships. This work builds on years of data and aims to identify which tests best forecast cognitive decline in PLWH. Results could help tailor monitoring and interventions to protect hearing and brain health in HIV patients.
Why it matters
Potential benefit: If successful, this work could lead to earlier detection of cognitive decline in people with HIV using hearing tests and inform strategies to protect brain health.
How similar studies have gone: Previous work in this cohort has shown that central auditory tests correlate with cognitive performance, supporting further exploration.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Buckey, Jay C — Dartmouth College
- Study coordinator: Buckey, Jay C
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Hearing changes in people with HIV and in people without HIV in Tanzania
This project follows people living with HIV and similar individuals in Tanzania to see how hearing and brain function relate over time and whether hearing tests can help predict cognitive changes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.