Condition

Atopic Dermatitis clinical trials and research

• 115Clinical trials
• 51NIH research projects
• 3New in 30 days
• 41Countries

Newest Atopic Dermatitis clinical trials

All recruiting trials (115)

• Roflumilast Cream 0.3% for moderate to severe atopic dermatitis in children, adolescents, and adults

  A cream called roflumilast 0.3% is tested once daily to see if it helps people with moderate to severe atopic dermatitis, compared to a non-medicated cream, across ages 6 and up.

  Recruiting at 4 sites Phase 3 Arcutis Biotherapeutics, Inc. · Birmingham, Alabama and 3 other locations · NCT07916480

• Nocturnal ScratchSense ring: test of automatic scratch detection in adults with itchy skin

  This study tests whether the Replior ScratchSense ring can accurately detect and measure nighttime scratching in adults with itchy skin conditions.

  Recruiting Replior AB · Grenoble · NCT07909967

• ADBest TREAT Registry for adults with atopic dermatitis

  A registry in Germany is collecting real-world data from adults with atopic dermatitis to see how treatments are used and how the disease affects quality of life.

  Recruiting Universitätsklinikum Hamburg-Eppendorf · Hamburg · NCT07904546

• How lebrikizumab affects the skin microbiome and mycobiome in adults with atopic dermatitis

  This study looks at whether lebrikizumab changes the skin bacteria, fungi, and specifically Staphylococcus species, in adults with moderate-to-severe atopic dermatitis.

  Recruiting University Hospital Bispebjerg and Frederiksberg · Copenhagen · NCT07807228

• QX-4533 safety study in healthy volunteers and people with moderate-to-severe atopic dermatitis

  This study tests the safety and tolerability of QX-4533, given as a pill, in healthy adults and in patients with moderate-to-severe atopic dermatitis to see how the drug behaves in the body and what side effects may occur.

  Recruiting Phase 1 QuantX Biosciences US Inc. · Shanghai, Shanghai Municipality · NCT07800104

• Tilrekimig for moderate-to-severe eczema in teens and adults

  A 52-week study will test tilrekimig against dupilumab and a placebo to see if it helps people 12 and older with moderate-to-severe atopic dermatitis.

  Recruiting at 31 sites Phase 3 Pfizer · Birmingham, Alabama and 49 other locations · NCT07783425

• TRIV-573 for moderate to severe atopic dermatitis in adults

  This study tests whether TRIV-573 can help adults with moderate to severe atopic dermatitis and checks its safety.

  Recruiting at 17 sites Phase 2 Triveni Bio · Fountain Valley, California and 16 other locations · NCT07782333

• Tilrekimig in adults and teens with eczema too severe for standard creams

  A new medicine called tilrekimig is being tested to see if it helps moderate-to-severe eczema in people 12 and older when used with medicated skin creams.

  Recruiting at 8 sites Phase 3 Pfizer · Birmingham, Alabama and 20 other locations · NCT07765888

• Nemolizumab vs placebo in Chinese teens and adults with moderate-to-severe atopic dermatitis

  This study tests whether Nemolizumab can help moderate-to-severe atopic dermatitis in Chinese participants aged 12 and up, compared with a placebo.

  Recruiting Phase 3 Galderma R&D · Hangzhou, Zhejiang · NCT07762833

• Probiotic Bifidobacterium bifidum for formula-fed infants with colic (with or without eczema)

  This study tests whether daily Bifidobacterium bifidum drops can reduce crying time in formula-fed infants 5 months or younger with colic, and whether it helps those with or without atopic dermatitis.

  Recruiting University of Roma La Sapienza · Roma, RM · NCT07754968

• See if IBI3027 works as well as Dupilumab for moderate to severe atopic dermatitis

  This study tests whether IBI3027 can help people with moderate to severe atopic dermatitis as effectively as Dupilumab injections.

  Recruiting Phase 3 Innovent Biologics (Suzhou) Co. Ltd. · Guangzhou, Guangdong · NCT07754786

• BYN-001 in healthy adults and adults with moderate to severe atopic dermatitis

  This first-in-human study tests BYN-001, a monoclonal antibody targeting IL-25, first in healthy adults and then in adults with moderate to severe atopic dermatitis to see if it is safe and how the body handles it.

  Recruiting Phase 1 Bionyra Pharma · Melbourne, Victoria · NCT07746817

• Digital mindfulness app for teens with eczema

  Teens with moderate to severe eczema try a digital mindfulness app to see if it helps control symptoms and improve quality of life.

  Recruiting at 2 sites Weill Medical College of Cornell University · New York, New York and 1 other locations · NCT07746427

• Non-Invasive Device for Early Detection of Atopic Dermatitis Flares

  This study tests whether a home-use device measuring skin properties can predict an eczema flare before symptoms appear in people aged 12–89 with a history of flares.

  Recruiting at 16 sites Castle Biosciences Incorporated · Phoenix, Arizona and 15 other locations · NCT07645820

• Env-294 in adults with moderate-to-severe atopic dermatitis

  This study tests three different doses of ENV-294 against placebo to see if it helps adults with moderate-to-severe atopic dermatitis after 12 weeks.

  Recruiting at 9 sites Phase 2 Enveda Therapeutics · Encinitas, California and 8 other locations · NCT07643766

• HL-300 ointment for mild-to-moderate atopic dermatitis

  This study tests different concentrations of HL-300 ointment vs placebo to see if it helps adults with mild-to-moderate atopic dermatitis.

  Recruiting Phase 1/2 Hangzhou Highlightll Pharmaceutical Co., Ltd · Hangzhou, Zhejiang · NCT07629778

• Camoteskimab in adults with moderate-to-severe atopic dermatitis

  This trial tests different doses of camoteskimab versus placebo to see if it helps adults with moderate-to-severe atopic dermatitis who have not fully responded to standard treatments.

  Recruiting at 31 sites Phase 2 Apollo Therapeutics Ltd · Birmingham, Alabama and 84 other locations · NCT07599813

• VC005 gel in adults with mild to moderate atopic dermatitis

  This study tests whether VC005 gel works better than a placebo gel for adults with mild to moderate atopic dermatitis.

  Recruiting Phase 2 Jiangsu vcare pharmaceutical technology co., LTD · Hangzhou, Zhejiang · NCT07598383

• VC005 for adults and teens with mild to moderate atopic dermatitis

  This study tests VC005 versus placebo to see if it helps people 12 and older with mild to moderate atopic dermatitis.

  Recruiting Phase 3 Jiangsu vcare pharmaceutical technology co., LTD · Nanjing, Jiangsu · NCT07592585

• Topical Roflumilast Cream for Itch in Atopic Dermatitis: See If It Helps Over 4 Weeks

  This trial tests whether a 0.15% topical roflumilast cream can reduce itching in people 12 years and older with mild to moderate atopic dermatitis over 4 weeks.

  Recruiting Phase 4 Integrative Skin Science and Research · Sacramento, California · NCT07560618

• First-in-human test of REGN20423 in healthy adults and adults with eczema

  This study tests REGN20423 in healthy adults and adults with atopic dermatitis to see how it behaves in the body and whether it helps eczema symptoms.

  Recruiting at 9 sites Phase 1 Regeneron Pharmaceuticals · Birmingham, Alabama and 8 other locations · NCT07527923

• SKB575 (HBM7575) injection in healthy adults and adults with atopic dermatitis

  This trial will test whether SKB575 (HBM7575) injection is safe and how it behaves in healthy adults and in adults with moderate to severe atopic dermatitis.

  Recruiting at 2 sites Phase 1 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. · Shanghai and 1 other locations · NCT07488065

• Dupilumab's effect on anxiety and depression in moderate-to-severe atopic dermatitis

  This project will see if dupilumab reduces anxiety and depression in people with moderate-to-severe atopic dermatitis who are starting or recently started the medicine.

  Recruiting at 4 sites Sanofi · Doha and 6 other locations · NCT07467564

• Low-sodium diet and salt tablets to see if eczema improves

  This study tests whether a low-sodium diet can lessen eczema symptoms in adults with atopic dermatitis, using a cross-over design with sodium tablets and placebo to see if salt intake changes skin sodium and severity.

  Recruiting at 2 sites Phase 4 University of California, San Francisco · San Francisco, California and 1 other locations · NCT07447063

• SM17 injections for moderate-to-severe atopic dermatitis

  This trial will test whether SM17 injections can reduce skin inflammation and itching in adults with moderate-to-severe atopic dermatitis who have not responded well to topical treatments.

  Recruiting Phase 2 SinoMab BioScience Ltd · Beijing · NCT07445919

• BioAmicus Complete probiotic drops for infant tummy and skin issues

  This test will see if daily BioAmicus Complete probiotic drops help infants (about 1 to 4 months old) with colic, constipation, diarrhea, reflux, or atopic dermatitis.

  Recruiting NovoNatum Ltd · Saint Petersburg · NCT07444008

• Soquelitinib for adults with moderate to severe atopic dermatitis

  This 12-week test gives adults with moderate to severe atopic dermatitis daily soquelitinib or a placebo to see if their skin and itch improve and to track side effects.

  Recruiting Phase 2 Corvus Pharmaceuticals, Inc. · South San Francisco, California · NCT07441395

• IBI3002 treatment for moderate to severe atopic dermatitis

  This Phase 2 study will test whether the injectable drug IBI3002 helps adults with moderate to severe atopic dermatitis compared with dupilumab and placebo.

  Recruiting Phase 2 Innovent Biologics (Suzhou) Co. Ltd. · Beijing, Beijing Municipality · NCT07399067

• Comparison of CKD-706 and US/EU Dupixent pharmacology in healthy adults.

  We will test whether CKD-706 behaves like the US and EU versions of Dupixent in healthy adults after a single 300 mg dose by measuring blood drug levels, immune response, and safety over 85 days.

  Recruiting Phase 1 Chong Kun Dang Pharmaceutical · Berlin, State of Berlin and 1 other locations · NCT07358156

• Relipid+ Balm in mild to moderate atopic dermatitis: a new emollient option for children and adults

  This study tests whether Baume Relipid+ can be used safely and effectively to help people with mild to moderate atopic dermatitis compare to current emollients.

  Recruiting University Hospital, Caen · Caen, Normandy · NCT07358000

• GX-03 topical treatment for adults with moderate to severe eczema

  This study will test whether applying GX-03, a topical emollient, twice daily for 8 weeks reduces eczema severity and itch in adults with moderate to severe atopic dermatitis compared with a petrolatum-based vehicle.

  Recruiting Phase 2/3 Turn Therapeutics · Irving, Texas · NCT07355075

• Retention of vernix caseosa after birth to help prevent eczema in newborns

  This study tests whether keeping the vernix on a newborn’s skin after birth can help prevent atopic dermatitis in infancy for healthy, full-term babies.

  Recruiting Pontificia Universidad Catolica de Chile · Las Condes, RM and 1 other locations · NCT07333378

• Oral roflumilast for people 12 and older with moderate-to-severe atopic dermatitis

  This 12-week pilot will test whether taking oral roflumilast once daily helps people aged 12 and older with moderate-to-severe atopic dermatitis.

  Recruiting Phase 2 Mansoura University Hospital · Al Mansurah, Dakahlia Governorate · NCT07297602

• Tracking teens and adults with atopic dermatitis who start or change systemic treatment

  This registry will follow people aged 12 and up with atopic dermatitis who start or switch systemic treatments to see how well the treatments work and how safe they are in everyday care.

  Recruiting at 81 sites Sanofi · Birmingham, Alabama and 81 other locations · NCT07290803

• Baricitinib for people with STAT3‑related Hyper‑IgE (Job) syndrome who have lupus-like disease or atopic dermatitis

  This trial will test whether the JAK inhibitor baricitinib can be taken safely and may reduce lupus-like symptoms or severe eczema in people aged 12 and older with STAT3-related Hyper‑IgE (Job) syndrome.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07262983

• PALLAS 311 nm UVB laser treatment for vitiligo, psoriasis, alopecia areata, and atopic dermatitis

  This study will test the PALLAS 311 nm UVB laser as an in-clinic, twice-weekly treatment for adults with vitiligo, psoriasis, alopecia areata, or atopic dermatitis for up to three months.

  Recruiting Szeged University · Szeged, Csongrád-Csanád Vármegye · NCT07250997

• Abrocitinib for eczema and patchy hair loss in people with Down syndrome

  This trial will test whether taking abrocitinib daily can help improve eczema or patchy hair loss in people with Down syndrome aged 12 and up.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07242638

• BBT001 in healthy adults and adults with moderate to severe atopic dermatitis

  This trial tests whether single and repeated doses of BBT001 are safe and well tolerated in healthy adults and in adults with moderate to severe atopic dermatitis.

  Recruiting Phase 1 Bambusa Therapeutics · Hefei, Anhui and 9 other locations · NCT07239947

• Non-Invasive Skin Fluid Biomarkers in Babies with and without Eczema

  This study tests whether a tiny, painless device can safely collect skin interstitial fluid from babies to see if eczema changes immune signals compared with healthy babies.

  Recruiting King's College London · London · NCT07228962

• A medicine for eczema: see if PF-08049820 helps adults with moderate to severe atopic dermatitis

  This study tests whether PF-08049820, taken as a daily pill, can safely help adults with moderate to severe eczema compared to a placebo.

  Recruiting at 41 sites Phase 2 Pfizer · Phoenix, Arizona and 51 other locations · NCT07216027

• ZL-82 tablets for adults with moderate to severe atopic dermatitis

  This trial will test whether taking ZL-82 tablets daily for 16 weeks can reduce eczema severity and itching in adults with moderate to severe atopic dermatitis compared with a placebo.

  Recruiting Phase 2 Chengdu Zenitar Biomedical Technology Co., Ltd · Chengdu, Sichuan · NCT07193589

• New ceramide‑and‑coconut‑oil skin barrier cream versus petrolatum for dry or irritated skin

  This study will test whether a new ceramide- and coconut oil–based cream can improve skin hydration and reduce dryness and itch in adults with mild to moderate psoriasis, atopic dermatitis, contact dermatitis, or xerosis.

  Recruiting Makati Medical Center · Makati City, National Capital Region · NCT07183423

• IMG-007 for adults with moderate-to-severe atopic dermatitis.

  This study will test if different doses of IMG-007 reduce skin inflammation and itching in adults with moderate-to-severe atopic dermatitis compared with a placebo.

  Recruiting at 23 sites Phase 2 Inmagene LLC · Lancaster, California and 29 other locations · NCT07037901

• Multiple-dose IBI3002 injections to check safety in adults with moderate-to-severe atopic dermatitis

  This trial will test multiple subcutaneous doses of IBI3002 in adults (18–65) with moderate-to-severe atopic dermatitis who haven't responded to or cannot use topical treatments.

  Recruiting Phase 1 The First Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT07015762

• RV4421B cream for tolerance and effectiveness in atopic dermatitis over 12 weeks

  This 12-week open-label test will try the marketed cream RV4421B-EV0407, alone or with topical steroid treatment, in infants, children, teens, and adults with mild-to-moderate atopic dermatitis to see if it is safe and improves their skin.

  Recruiting Pierre Fabre Dermo Cosmetique · Quatre Bornes, Mauritius · NCT07014007

• Long-term safety and effectiveness of APG777 in moderate-to-severe atopic dermatitis

  This long-term extension will see if continued APG777 is safe and helpful for people with moderate-to-severe atopic dermatitis who completed a prior APG777 study.

  Recruiting at 80 sites Phase 2 Apogee Therapeutics, Inc. · Fountain Valley, California and 79 other locations · NCT07003425

• Skin salt levels and their link to eczema in adults 50 and older

  This project will test whether diet and skin barrier problems affect salt levels in the skin and whether those salt levels relate to eczema in people aged 50 and older.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 1 other locations · NCT06998446

• Evaluating full-body imaging technology for skin disease detection

  This study is testing a new full-body imaging technology to see if it can help doctors better detect and monitor skin diseases like skin cancer and eczema.

  Recruiting at 3 sites HJN Sverige AB/Neko Health · Stockholm and 2 other locations · NCT06989216

• Nemolizumab for moderate-to-severe atopic dermatitis in adolescents and adults

  This will try nemolizumab in adolescents and adults with moderate-to-severe atopic dermatitis to see if it improves symptoms and patient-reported outcomes over six months.

  Recruiting at 81 sites Galderma R&D · Birmingham, Alabama and 107 other locations · NCT06988605

• Understanding skin structure in atopic dermatitis

  This study looks at the skin of people with atopic dermatitis to see how it changes and to help improve treatment options.

  Recruiting Sheffield Teaching Hospitals NHS Foundation Trust · Sheffield, South Yorkshire · NCT06954272

• Testing new treatments for moderate to severe atopic dermatitis

  This trial will test an experimental medicine called GHZ339 (compared with placebo) to see if it reduces symptoms in people with moderate to severe atopic dermatitis.

  Recruiting at 69 sites Phase 2 Novartis · Birmingham, Alabama and 104 other locations · NCT06947993

• CM512 for adults with moderate-to-severe atopic dermatitis

  This study will test whether CM512 helps adults with moderate-to-severe atopic dermatitis reduce itching and improve skin lesions compared with a placebo.

  Recruiting Phase 2 Keymed Biosciences Co.Ltd · Beijing · NCT06947980

• Testing QLS12010 Capsules in Healthy Adults

  This study is testing if QLS12010 Capsules are safe and how well they are tolerated by healthy adults while also looking at how food affects the way the body absorbs the drug.

  Recruiting Phase 1 Shanghai Qilu Pharmaceutical Research and Development Center LTD · Beijing · NCT06946641

• Abrocitinib for moderate-to-severe atopic dermatitis after inadequate response to biologics

  This study will try abrocitinib in adolescents and adults (≥12 years) with moderate-to-severe atopic dermatitis who didn't respond to or couldn't tolerate up to two biologic treatments to see how it works in routine care.

  Recruiting Pfizer · San Diego, California · NCT06899204

• Evaluating the effectiveness of target therapies for atopic dermatitis

  This study is testing how well certain new treatments for moderate-to-severe atopic dermatitis work over a year for adults who are starting or already using them.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT06882148

• QLM3003 ointment for adults with mild to moderate atopic dermatitis

  This trial will test whether applying QLM3003 ointment (1.5% or 2%) twice daily for 8 weeks helps adults with mild to moderate atopic dermatitis compared with a placebo.

  Recruiting Phase 3 Qilu Pharmaceutical Co., Ltd. · Shenyang · NCT06880276

• Testing a new hydrogel for treating mild to moderate eczema

  This study is testing a new hydrogel called zabalafin to see if it helps people with mild to moderate eczema feel better compared to a placebo.

  Recruiting at 12 sites Phase 2 Alphyn Biologics · Brookvale, New South Wales and 11 other locations · NCT06855745

• Herbal ointment for treating atopic dermatitis

  This study is testing a herbal ointment made from a plant to see if it can help people with atopic dermatitis feel better.

  Recruiting Phase 2/3 En Chu Kong Hospital · New Taipei City · NCT06850311

• Evaluating the effects of lebrikizumab on well-being in adults with moderate-to-severe atopic dermatitis

  This study is testing how the medication lebrikizumab affects the well-being and skin symptoms of adults with moderate-to-severe atopic dermatitis in everyday settings.

  Recruiting Almirall, S.A. · Aarhus, Denmark · NCT06815380

• Testing BBT001 in healthy volunteers and adults with atopic dermatitis

  This study is testing a new drug called BBT001 in healthy people and adults with atopic dermatitis to see if it's safe and effective.

  Recruiting at 12 sites Phase 1 Bambusa Therapeutics · Irvine, California and 13 other locations · NCT06808477

• Long-term abrocitinib oral suspension treatment for children 2 years and older with moderate-to-severe eczema

  This 24-month trial will try a liquid form of the medicine abrocitinib, with or without topical medicines, in children aged 2 years and older who have moderate-to-severe eczema to see if it is safe and helps their skin over time.

  Recruiting at 34 sites Phase 3 Pfizer · Birmingham, Alabama and 39 other locations · NCT06807281

• Public reactions to facial psoriasis, atopic dermatitis, vitiligo, and alopecia areata

  This project tests how adults in the general population emotionally and socially respond to faces showing psoriasis, atopic dermatitis, vitiligo, or alopecia areata.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma, Italia · NCT06801821

• Evaluating ICP-332 for treating moderate to severe atopic dermatitis

  This study is testing a new oral medication called ICP-332 to see if it can help people with moderate to severe atopic dermatitis who haven't found relief from other treatments.

  Recruiting at 62 sites Phase 3 Beijing InnoCare Pharma Tech Co., Ltd. · Hefei, Anhui and 61 other locations · NCT06775860

• Treatment for moderate to severe atopic dermatitis in adolescents

  This study is testing a new injection called MG-K10 to see if it can safely help teenagers aged 12 to 18 with moderate to severe eczema feel better.

  Recruiting Phase 1/2 Shanghai Mabgeek Biotech.Co.Ltd · Hangzhou, Zhejiang · NCT06765005

• Examining the effects of ruxolitinib cream versus topical corticosteroids in pregnant women with atopic dermatitis

  This study is testing whether using ruxolitinib cream during pregnancy is safer for babies than using regular steroid creams in women with atopic dermatitis.

  Recruiting Incyte Corporation · Morrisville, North Carolina · NCT06627335

• Biomarkers that predict how skin-disease treatments will work

  Researchers are testing blood and skin markers to see if they can forecast which patients with inflammatory skin diseases will respond to systemic treatments over a year.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT06599411

• Assessing PG-011 Gel for Treating Atopic Dermatitis in Adolescents and Adults

  This study is testing a new gel called PG-011 to see if it can help teenagers and adults with mild to moderate eczema feel better.

  Recruiting Phase 3 Prime Gene Therapeutics Co., Ltd. · Shenyang, Liaoning · NCT06587685

• Evaluating PF-07832837 for safety and tolerability in healthy adults and patients with atopic dermatitis

  This study is testing a new drug called PF-07832837 to see if it's safe and tolerable for both healthy adults and adults with moderate to severe atopic dermatitis.

  Recruiting at 5 sites Phase 1 Pfizer · Anaheim, California and 7 other locations · NCT06564389

• Dietary changes to manage atopic dermatitis

  This study is testing whether changing to a high-fat or plant-based diet can help people with atopic dermatitis manage their symptoms better.

  Recruiting National University of Singapore · Singapore, Singapore · NCT06547372

• Assessing molecular changes in adults with moderate to severe skin conditions receiving Lutikizumab

  This study is testing a new drug called Lutikizumab to see if it can help adults with moderate to severe skin conditions like hidradenitis suppurativa and atopic dermatitis feel better.

  Recruiting at 2 sites Phase 2 AbbVie · Sacramento, California and 1 other locations · NCT06524635

• Investigating a new treatment for atopic dermatitis using a specific bacteria

  This study is testing a new gel made with a specific bacteria to see if it helps teenagers and adults with atopic dermatitis who have a certain skin bacteria.

  Recruiting at 7 sites Phase 1 National Institute of Allergy and Infectious Diseases (NIAID) · San Diego, California and 7 other locations · NCT06504160

• Evaluating the effects of FB825 for moderate-to-severe atopic dermatitis

  This study is testing a new treatment called FB825 to see if it can help adults with moderate-to-severe atopic dermatitis feel better.

  Recruiting at 16 sites Phase 2 Oneness Biotech Co., Ltd. · Fountain Valley, California and 15 other locations · NCT06397911

• Research on improving kindergarten yards for children's health

  This study is testing whether making kindergarten yards more natural and full of plants can improve the health and learning of children aged 1-5 by looking at things like allergies, asthma, and their overall well-being.

  Recruiting at 2 sites Natural Resources Institute Finland · Helsinki, Uusimaa and 1 other locations · NCT06390878

• Exploring how playing in sand affects atopic dermatitis in children

  This study is testing if playing in sand can help young children with eczema feel better by looking at their skin and immune system changes.

  Recruiting at 2 sites Natural Resources Institute Finland · Helsinki, Uusimaa and 1 other locations · NCT06390696

• AI app to help manage atopic dermatitis

  This study is testing a new AI app designed to help people with atopic dermatitis manage their skin condition better by using images to track and evaluate their symptoms.

  Recruiting West China Hospital · Chengdu, Sichuan · NCT06362629

• National Register for Adults with Moderate to Severe Atopic Dermatitis

  This study is collecting information from adults with moderate to severe atopic dermatitis to better understand the condition and improve treatment options.

  Recruiting Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse · Brescia, Brescia · NCT06313333

• Evaluating Tralokinumab with Corticosteroids for Atopic Dermatitis in Children

  This study is testing if a new injection combined with skin creams can help children and infants with moderate-to-severe eczema feel better.

  Recruiting at 23 sites Phase 3 LEO Pharma · Birmingham, Alabama and 71 other locations · NCT06311682

• Exploring links between food allergies and atopic dermatitis

  This study is trying to see if there are connections between food allergies and atopic dermatitis by looking at blood and skin samples from people with and without these conditions.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06300697

• Comparing outcomes for pregnant women with atopic dermatitis using ruxolitinib cream

  This study is trying to see if using ruxolitinib cream during pregnancy is safe for women with mild to moderate atopic dermatitis and their babies compared to those who don’t use it.

  Recruiting Incyte Corporation · Morrisville, North Carolina · NCT06259669

• Topical treatment for atopic dermatitis

  This study is testing if teaching patients the right way to use a cream for atopic dermatitis can help them stick to their treatment better and improve their skin condition.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT06244212

• Registry for adolescents with atopic dermatitis to assess treatment safety and effectiveness

  This study is trying to see how safe and effective different treatments are for teenagers aged 12 to 15 with moderate to severe eczema.

  Recruiting CorEvitas · Waltham, Massachusetts · NCT06238765

• Observing how adolescents with severe atopic dermatitis respond to dupilumab treatment

  This study looks at how well dupilumab treatment works for teenagers aged 12 to 17 with severe eczema over a year, focusing on their symptoms and quality of life.

  Recruiting at 9 sites Sanofi · Bologna and 8 other locations · NCT06192563

• Virtual reality game to reduce pain and anxiety during dupilumab injections

  This project will test whether a virtual reality game can reduce pain and anxiety for children aged 6–17 during dupilumab injections for moderate to severe atopic dermatitis.

  Recruiting at 2 sites St. Justine's Hospital · Montreal, Quebec and 1 other locations · NCT06182436

• Registry for patients with pediatric atopic dermatitis receiving systemic treatments

  This study is creating a registry for kids with severe eczema who are using or planning to use systemic treatments to help researchers learn more about how well these treatments work and keep everyone updated on new options.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06136767

• Topical treatment for eczema using cardamom and a beneficial bacteria

  This study is testing a new cream made with cardamom and a helpful bacteria to see if it can improve eczema symptoms in people aged 2 and older.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06096857

• Investigating a new injection for moderate to severe atopic dermatitis

  This study is testing a new injection for people with moderate to severe atopic dermatitis to see if it can help improve their symptoms when other treatments haven't worked well.

  Recruiting at 3 sites Phase 1 Brexogen Inc. · North Little Rock, Arkansas and 2 other locations · NCT06055361

• Collecting samples from people with skin conditions and healthy volunteers

  This study is collecting samples from people with different skin conditions and healthy volunteers to see how their biology differs and learn more about these conditions.

  Recruiting Innovaderm Research Inc. · Montreal, Quebec · NCT05994976

• Monitoring pregnancy and infant outcomes after tralokinumab exposure

  This study looks at how using the medication tralokinumab during pregnancy affects both the pregnancy and the baby's health compared to pregnant individuals with atopic dermatitis who didn't use the drug.

  Recruiting University of California, San Diego · La Jolla, California · NCT05938478

• Understanding the factors influencing chronic inflammatory skin diseases

  This study is trying to understand what causes different types of chronic skin conditions, like eczema and psoriasis, to behave differently in patients over time.

  Recruiting University Hospital Schleswig-Holstein · Kiel · NCT05928169

• Examining how dupilumab affects immune cells in atopic dermatitis

  This study is testing how the medication dupilumab affects immune cells in the skin of people with moderate to severe atopic dermatitis.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT05858619

• Registry for patients with moderate-to-severe atopic dermatitis in Switzerland

  This study is creating a national registry to track the care and experiences of people aged 12 and older with moderate-to-severe atopic dermatitis in Switzerland to better understand the condition and its impact.

  Recruiting at 8 sites Swiss Society of Dermatology and Venereology · Basel and 8 other locations · NCT05819463

• Exploring the connection between skin inflammation and mental health in atopic eczema

  This study looks at how skin inflammation and itching in people with severe eczema affect their mental health and brain function to see if treating the eczema can improve their overall well-being.

  Recruiting King's College London · London · NCT05790330

• Safety of Abrocitinib in Pregnant Women and Their Babies

  This study is testing whether the medication abrocitinib is safe for pregnant women and their babies compared to women with similar skin conditions who haven't taken the drug.

  Recruiting Pfizer · New York, New York · NCT05721937

• Learning about Abrocitinib for treating moderate to severe atopic dermatitis in adults

  This study is testing if taking Abrocitinib daily can safely help adults with moderate to severe atopic dermatitis feel better over two years.

  Recruiting at 30 sites Pfizer · Amiens, Somme and 29 other locations · NCT05689151

• Cosmetic cream for treating very dry and irritated skin in children

  This study is testing a new cream for children with very dry and irritated skin to see if it helps improve their skin condition better than a fake cream.

  Recruiting NAOS Argentina S.A. · Ciudad Autónoma de Buenos Aire, Ciudad Autónoma de Buenos Aire and 2 other locations · NCT05575882

• Using Dupixent and UVB therapy for treating atopic dermatitis

  This study is testing if combining a medication called Dupixent with UVB light therapy can help people with moderate to severe eczema feel better.

  Recruiting Phase 4 Psoriasis Treatment Center of Central New Jersey · East Windsor, New Jersey · NCT05285839

• Exploring how dupilumab works differently in various ethnic groups with atopic dermatitis

  This study is testing how well dupilumab works for people with atopic dermatitis from different ethnic backgrounds, like Caucasian, Asian, and African American, to see if their responses vary.

  Recruiting Phase 4 University of Michigan · Ann Arbor, Michigan · NCT05268107

• Investigating the skin microbiome in patients with atopic dermatitis receiving systemic therapy

  This study looks at how the skin bacteria of people with moderate to severe atopic dermatitis change while they are on systemic treatments to see if it can help improve their care and understanding of the condition.

  Recruiting Charite University, Berlin, Germany · Berlin, State of Berlin · NCT05099315

• Improving sleep and skin symptoms in children with eczema using Dupilumab

  This study is testing if the medication Dupilumab can help improve sleep and skin symptoms in children aged 6 to 17 with moderate to severe eczema.

  Recruiting Phase 4 Northwestern University · Chicago, Illinois · NCT05042258

• Characterizing chronic hand eczema and its impact on quality of life

  This study is trying to understand different types of chronic hand eczema and atopic dermatitis in adults to see how they affect daily life and what factors might make them worse.

  Recruiting Innovaderm Research Inc. · Montreal, Quebec · NCT05026554

• Exploring immune responses in diseases like psoriasis and eczema

  This study is trying to see how the immune system works in people with psoriasis and eczema, as well as healthy volunteers, to better understand their skin healing and find new treatment options.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04864886

• How often eyelids are affected in adults with atopic dermatitis

  This project will see how often adults with atopic dermatitis have eyelid (palpebral) involvement and will try patch-testing to look for possible allergic causes.

  Recruiting at 2 sites University Hospital, Lille · Lille and 1 other locations · NCT04826744

• Atopic Dermatitis Registry: See how approved treatments work for adults under dermatology care

  This is a nationwide registry that follows adults with atopic dermatitis to see how safe and effective approved treatments are in real-world dermatology settings.

  Recruiting CorEvitas · Waltham, Massachusetts · NCT04504955

• Investigating the role of a genetic variant in worsening atopic dermatitis

  This study is trying to see if a specific genetic change is connected to worse atopic dermatitis in people aged 6 to 65.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT04455906

• Modified Qing-Ying Decoction for Atopic Dermatitis in Children

  This study tests whether the modified Qing-Ying Decoction can help improve symptoms and quality of life for children with subacute to chronic atopic dermatitis, compared with a placebo.

  Recruiting Phase 2/3 Chinese University of Hong Kong · Hong Kong · NCT04419584

• Creating a database for patients with immune-mediated inflammatory diseases

  This study is creating a database and biobank for patients with immune-related diseases to see if new information can help improve treatments and understand their conditions better.

  Recruiting University Hospital, Lille · Lille · NCT04334031

• Long-term observation of atopic dermatitis and related allergic conditions

  This project will collect medical and lab data over time to see which genetic, immune, environmental, and microbial factors relate to the course or remission of atopic dermatitis and other atopic diseases in people of all ages.

  Recruiting University of Zurich · Zurich, Canton of Zurich · NCT04240522

• Understanding skin bacteria in patients with eczema and psoriasis

  This study is trying to see how skin bacteria affect people with eczema and psoriasis to better understand their skin health and treatment responses.

  Recruiting University of Rochester · Rochester, New York · NCT04170244

• Restoring microbiota in newborns delivered by cesarean section

  This study is testing if exposing newborns delivered by cesarean section to their mother’s vaginal and fecal bacteria right after birth can help lower their chances of developing allergies by age two.

  Recruiting Karolinska Institutet · Stockholm, Stockholm County · NCT03928431

• Registry for new treatments in patients with atopic dermatitis

  This study is collecting information from people with atopic dermatitis to see how well new treatments work and how they affect other related conditions like food allergies and asthma.

  Recruiting at 14 sites UMC Utrecht · Nijmegen, Gelderland and 13 other locations · NCT03549416

• Investigating disease progression and treatment responses in atopic dermatitis and psoriasis

  This study is looking at how atopic dermatitis and psoriasis change over time and how different treatments work for people with these skin conditions.

  Recruiting University Hospital Schleswig-Holstein · Kiel · NCT03361215

• Exploring molecular profiles in inflammatory skin diseases

  This study is trying to see how different biological factors in the skin affect psoriasis and atopic dermatitis, and how treatments can help manage these conditions better.

  Recruiting University Hospital Schleswig-Holstein · Kiel · NCT03358693

• Understanding the genetics and natural history of food allergies and related conditions

  This study is trying to understand the causes of food allergies and related conditions by looking at the genetics and health history of people with food allergies, their families, and healthy volunteers over several years.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT02504853

• Examining skin microbes in healthy individuals and those with eczema

  This study looks at the tiny germs on the skin of healthy people and those with eczema to see how they differ and what that might mean for skin health.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00605878

• Collection of blood, urine, and tissue samples for research on skin conditions

  This study is collecting blood, urine, and tissue samples from people with skin conditions like cutaneous T-cell lymphoma, eczema, and atopic dermatitis to help improve treatments in the future.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT00177268

NIH-funded research (newest 40 of 51)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Stopping Atopic Dermatitis and Allergy: Preventing Food Allergy by Protecting the Skin

  A large study in infants at high risk for allergies tests whether using a skin barrier cream together with early, proactive skin care can prevent peanut allergy and other food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11532535

• SEAL Study: Preventing peanut allergy by protecting baby skin

  This trial tests whether using a skin-emollient and proactive skin steroids early in life can prevent peanut allergy in high-risk infants.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11532533

• SEAL Study: Prevent allergy by protecting the baby’s skin

  A very young group of high-risk babies will try a early skin-care plan to reduce eczema and prevent peanut allergy.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11516452

• Understanding how skin fungi affect atopic dermatitis in adults

  A study will look at how the skin's fungal community influences atopic dermatitis in adults and whether this understanding could lead to new treatments.

  NIH research Dartmouth-Hitchcock Clinic · Lebanon, United States · NIH-11435642

• Preventing eczema-related allergies by strengthening infants' skin barrier

  This project will see if using a trilipid skin cream plus proactive mild topical steroids in infants with early dry skin or eczema lowers their chances of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11418544

• Personalized predictions for how atopic dermatitis may progress in kids and teens

  A patient-friendly plan to forecast how early-onset eczema might evolve in children and young people using simple health clues and data from diverse settings.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11418025

• Sodium in the Skin and Atopic Dermatitis

  This grant looks at how salt in the skin relates to eczema and whether reducing salt could help people with atopic dermatitis.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11413363

• AB-101: a first-in-class botanical gel to fight skin infections in adults with atopic dermatitis

  A new topical gel from a plant source aims to clear skin bacteria, reduce itching and inflammation, and help repair the skin barrier in adults with atopic dermatitis.

  NIH research Alphyn Biologics, INC. · Annapolis, United States · NIH-11409719

• Role of skin and gut microbes in starting atopic dermatitis in babies

  This grant examines how microbes on the skin and in the gut may influence the development of atopic dermatitis in infants.

  NIH research Washington State University · Pullman, United States · NIH-11406309

• SEAL: Stopping eczema and allergy by protecting the skin in infants

  A large clinical study in early infancy tests whether using a skin barrier cream together with a gentle anti-inflammatory cream can reduce the chance of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11406152

• Preventing food allergies by protecting babies' skin

  This trial tests whether starting a trilipid moisturizer plus early gentle topical steroids for babies with dry skin or early eczema can lower their chance of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11393205

• Preventing food allergy by strengthening babies' skin barrier

  See if giving a trilipid emollient plus proactive topical steroid treatment to infants with very early dry skin or eczema can lower their chance of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11392091

• T-Cell Plasticity and Treatment Resistance in Atopic Dermatitis

  A study exploring how certain immune cells change their behavior in people with atopic dermatitis and how this influences treatment responses and side effects.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11389364

• Basophil-fibroblast signals driving inflammation in atopic dermatitis

  A study in mouse models and human tissue samples looks at how basophils and fibroblasts talk to each other to fuel skin inflammation in atopic dermatitis.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11367733

• Cord blood DNA marks linked to early-onset pediatric atopic dermatitis

  A study will look at cord blood DNA methylation to find early clues for kids who develop atopic dermatitis and related allergies.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11365750

• Mapping eczema biology across ethnic groups and levels of severity

  This project looks at skin and blood differences in adults with moderate-to-severe atopic dermatitis across different ethnic groups to help match treatments to each person's type of eczema.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11332655

• What affects eczema (atopic dermatitis) in adults living in a city neighborhood

  Researchers will follow racially and ethnically diverse adults with eczema in a North Philadelphia neighborhood to learn how housing, neighborhood, and social factors relate to skin symptoms and quality of life.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11323015

• Microbiome function in atopic dermatitis: understanding skin bacteria to help people with AD

  A study is exploring how skin bacteria affect atopic dermatitis in both kids and adults and testing ways to support helpful bacteria to improve the skin.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11319829

• Coordinating national research on atopic dermatitis (eczema)

  A national effort that brings researchers together to better understand different types of eczema and speed development of more targeted treatments for people with atopic dermatitis.

  NIH research National Jewish Health · Denver, United States · NIH-11314555

• How IL-18 causes inflammation and itch in eczema

  Researchers are learning whether a protein called IL-18 drives the inflammation and itch of atopic dermatitis in children and adults.

  NIH research Washington University · Saint Louis, United States · NIH-11311825

• Center to understand and treat eczema (atopic dermatitis)

  This project looks at biological differences in people with different types of atopic dermatitis, including those prone to eczema herpeticum and those with food allergy, to help improve care for children and adults.

  NIH research National Jewish Health · Denver, United States · NIH-11310152

• How eczema (atopic dermatitis) progresses in children

  This project follows children with eczema to find patterns in their skin, gut, airways, and blood that predict who may develop allergies or asthma.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11307661

• How genes and skin bacteria affect eczema severity

  This project looks at whether a common gene change and Staphylococcus aureus on the skin make eczema worse in children and adults and whether removing the bacteria helps.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11301854

• Improving safety checks for new eczema (atopic dermatitis) medicines in real-world patients

  This work looks for safety problems with new immune-targeting eczema medicines using health records from millions of Americans, including children, pregnant-age women, and other groups often left out of clinical trials.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11289419

• How Staph on the skin may worsen food allergy in eczema

  This work tests whether Staphylococcus aureus on eczema skin makes severe food allergies more likely and whether blocking gut leakiness can reduce those reactions for people with atopic dermatitis.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11284058

• Salt in the Skin and Eczema

  This project tests whether high salt in the diet and skin makes atopic dermatitis worse and whether lowering salt can help people with eczema.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11187118

• Skin-friendly probiotics to calm atopic dermatitis

  A small, carefully tested therapy using a safe, non-pathogenic bacteria to deliver protease inhibitors directly to damaged skin to help people with atopic dermatitis feel better.

  NIH research Resvita Bio, INC. · Berkeley, UNITED STATES · NIH-11186606

• Investigating how a bacteria affects skin inflammation in atopic dermatitis

  This study is looking at how a common skin bacteria called Staphylococcus aureus affects inflammation in people with atopic dermatitis, using mice to help understand how it interacts with skin cells, with the hope of finding better treatments for those dealing with this skin condition.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11161370

• Understanding the connection between skin and nerves in atopic dermatitis itch

  This research explores how skin and nerve cells communicate to cause the persistent itch experienced by children and adolescents with atopic dermatitis.

  NIH research North Carolina State University Raleigh · Raleigh, United States · NIH-11138744

• Understanding and treating genetic issues in overlapping skin conditions like psoriasis and atopic dermatitis

  This study is looking at the genetic differences in people who have both psoriasis and atopic dermatitis, to see how these differences can help doctors choose the best treatments for their skin conditions.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11133500

• Understanding how social and environmental factors affect atopic dermatitis in urban adults

  This study is looking at how things like your surroundings and social life affect adults with atopic dermatitis (AD) in urban areas, especially in North Philadelphia, to better understand how these factors impact the severity of the condition and the quality of life for people dealing with it.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11115772

• How the skin protein filaggrin affects childhood eczema and later allergies

  This work looks at how levels of the skin protein filaggrin in young children with eczema may increase the chance of developing food allergies, hay fever, or asthma.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11103189

• Preventing childhood food allergy by strengthening babies' skin barrier

  This trial tests whether using a trilipid moisturizer daily plus early mild topical steroid treatment for infants with early dry skin or eczema can lower their chance of developing food allergies.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11093911

• Understanding and treating atopic dermatitis and its related conditions

  This study is looking at different types of atopic dermatitis to better understand how it affects the skin and immune system, and it offers patients a chance to join trials that could lead to better treatments for their condition.

  NIH research National Jewish Health · Denver, United States · NIH-11079574

• Understanding the role of skin bacteria in atopic dermatitis

  This study is looking at how the good and bad bacteria on our skin affect atopic dermatitis, a common skin condition, and aims to find ways to help the good bacteria thrive to improve skin health for both kids and adults.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11078829

• Investigating genetic and microbial factors that affect the severity of Atopic Dermatitis.

  This study is looking at how certain genes and skin bacteria might affect how bad Atopic Dermatitis (AD) can get, and it's for people of all ages who have this condition.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11066508

• Understanding how IL-18 affects atopic dermatitis

  This study is looking at how a substance called IL-18 affects atopic dermatitis, a skin condition that causes itching and inflammation, to help find new ways to treat it.

  NIH research Washington University · Saint Louis, United States · NIH-11064050

• Understanding how atopic dermatitis progresses in children

  This study is looking at how atopic dermatitis, a common skin issue in kids, can affect their overall health and lead to allergies, by tracking how things like skin, gut, and breathing health play a role in its development.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11063101

• How atopic dermatitis affects children's brain function

  This study is looking at how eczema might affect kids' thinking and learning skills, and it’s for children who have eczema to help find ways to support their learning better.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11061116

• Understanding different types of atopic dermatitis and their treatments

  This study is looking at different types of atopic dermatitis (AD) to better understand how symptoms and genetics affect the condition, and it invites patients to join in clinical trials that could lead to new treatments and a deeper understanding of their skin issues.

  NIH research National Jewish Health · Denver, United States · NIH-11056042

Related topics

Quick answers

How many Atopic Dermatitis clinical trials are recruiting right now?

115, as of November 12, 2026. 3 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 41 countries. The most sites are in United States (51 trials), China (23 trials), Canada (12 trials), Germany (12 trials), France (10 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 19, Phase 1: 13, Phase 3: 11, Phase 4: 6. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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