Investigating disease progression and treatment responses in atopic dermatitis and psoriasis
Official title: Disease Trajectories in Atopic Dermatitis and Psoriasis
Run by University Hospital Schleswig-Holstein · NCT03361215 · Data updated 2026-11-12
This study is looking at how atopic dermatitis and psoriasis change over time and how different treatments work for people with these skin conditions.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 0 Years to 100 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University Hospital Schleswig-Holstein Academic / other |
| Locations | 1 site (Kiel) |
| Status | Recruiting |
| Started | March 16, 2015 |
| Main results expected | March 15, 2028 |
| Study ends | December 31, 2030 |
| Registry record updated | July 22, 2025 |
| Trial ID | NCT03361215 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with a clinical diagnosis of atopic dermatitis, psoriasis, or other autoimmune skin diseases who can provide informed consent.
✕Probably not a fit
Patients who decline participation or are under 18 years of age will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on the long-term progression of atopic dermatitis and psoriasis, chronic inflammatory skin diseases. Participants will undergo regular examinations and provide biological samples, including blood, skin biopsies, and swabs, to analyze inflammation and gene expression. The study aims to monitor disease changes over at least ten years, assessing the impact of targeted therapies on clinical and molecular levels. By collecting extensive clinical and biological data, the research seeks to enhance understanding of these conditions and their treatment.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of atopic dermatitis and psoriasis, potentially enhancing treatment outcomes for patients.
How similar studies have gone: Other studies have shown success in understanding disease mechanisms and treatment responses in similar chronic inflammatory conditions, indicating that this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with a clinical diagnosis of atopic dermatitis, psoriasis or autoimmune skin disease * Written informed consent obtained from the subject Exclusion Criteria: * Patients who decline participation In patients\<18 years of age no biopsies will be taken
Where it's running
-
Department of Dermatology, University Hospital Schleswig Holstein, Campus Kiel
Kiel, Germany Recruiting
Study contacts
- Principal investigator: Stephan Weidinger, Prof. Dr. — Dept. of Dermatology University Hospital Kiel
- Study coordinator: Stephan Weidinger, Prof. Dr.
- Email: sweidinger@dermatology.uni-kiel.de
- Phone: +49431500
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.