Collecting samples from people with skin conditions and healthy volunteers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect various biological samples from individuals with different inflammatory skin conditions, such as acne, atopic dermatitis, chronic hand eczema, hidradenitis suppurativa, and plaque psoriasis, as well as from healthy volunteers. The collected samples will be used for molecular characterization, including biomarker and gene expression analyses. Participants will undergo procedures to collect blood, oral, hair, skin samples, and skin surface materials to facilitate this research.

Why it matters

Who can join: the full rules

Inclusion Criteria:

All subjects:

1. Subject is willing to participate and is capable of giving informed consent. Note: Consent must be obtained prior to any study-related procedures.
2. Subject must be willing to comply with all study procedures and must be available for the duration of the study.

   Healthy volunteers:
3. Male or female subject aged 18 years or older, at the time of consent.
4. Subject is in good general health, according to the investigator's judgment.

   Subjects with Acne:
5. Male or female subject aged 18 to 45 years old, inclusive, at the time of consent.

   Subjects with AD:
6. Male or female subject aged 18 years or older, at the time of consent.
7. Subject has clinically confirmed diagnosis of active AD, according to Hanifin and Rajka criteria.

   Subjects with CHE:
8. Male or female subject aged 18 years or older, at the time of consent.
9. Subject has at least a 6-month history of CHE before Screening (information obtained from medical chart or subject's physician, or directly from the subject).

   Subjects with HS:
10. Male or female subject aged 18 years or older, at the time of consent.
11. Subject has a clinically confirmed diagnosis of active HS with a disease duration of ≥ 6 months before screening as determined by the investigator through subject interview and/or review of the medical history.

    Subjects with PPP:
12. Male or female subject aged 18 years or older at the time of consent.
13. Subject has at least a 6-month history of PPP as defined by the presence of pustules on palms and/or soles, but without evidence of infection on palms and soles (information obtained from medical chart or subject's physician, or directly from the subject).

    Subjects with psoriasis:
14. Male or female subject aged 18 years or older, at the time of consent.

Exclusion Criteria:

All subjects:

1. Subject is a female who is pregnant or who is planning to become pregnant during the study.
2. Subject has a history of skin disease or presence of skin condition that, in the opinion of the investigator, would interfere with the study assessments.

Where it's running

• Innovaderm Research Inc.
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Robert Bissonnette, MD — Innovaderm Research Inc.
• Study coordinator: Julie Bedoucha, MSc
• Email: jbedoucha@innovaderm.com
• Phone: 514-521-4285

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Understanding the factors influencing chronic inflammatory skin diseases

  This study is trying to understand what causes different types of chronic skin conditions, like eczema and psoriasis, to behave differently in patients over time.

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• Characterizing chronic hand eczema and its impact on quality of life

  This study is trying to understand different types of chronic hand eczema and atopic dermatitis in adults to see how they affect daily life and what factors might make them worse.

  Recruiting Innovaderm Research Inc. · Montreal, Quebec · NCT05026554

• Adapalene/Clindamycin Gel in Vietnamese Acne Patients

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• Roflumilast Cream 0.3% for moderate to severe atopic dermatitis in children, adolescents, and adults

  A cream called roflumilast 0.3% is tested once daily to see if it helps people with moderate to severe atopic dermatitis, compared to a non-medicated cream, across ages 6 and up.

  Recruiting at 4 sites Phase 3 Arcutis Biotherapeutics, Inc. · Birmingham, Alabama and 3 other locations · NCT07916480

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.