Understanding different types of atopic dermatitis and their treatments
Official title: ATOPIC DERMATITIS RESEARCH NETWORK (ADRN) CLINICAL RESEARCH CENTER
Funded at National Jewish Health · NIH-11056042 · Data updated 2026-11-12
This study is looking at different types of atopic dermatitis (AD) to better understand how symptoms and genetics affect the condition, and it invites patients to join in clinical trials that could lead to new treatments and a deeper understanding of their skin issues.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project start | April 10, 2020 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $329,638 |
| NIH project number | 5U01AI152037-06 |
| Project ID | NIH-11056042 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals of all ages with atopic dermatitis, particularly those with specific symptoms like eczema herpeticum or food allergies.
✕Less likely to help
Patients with atopic dermatitis who do not fit into the specified phenotypes or who have other unrelated skin conditions may not benefit from this research.
What this research studies
This research focuses on atopic dermatitis (AD), a common skin condition, by examining different patient groups based on their specific symptoms and genetic factors. It aims to establish a clinical and laboratory infrastructure to support the evaluation of three distinct phenotypes of AD: those with a tendency for eczema herpeticum, those without, and those with food allergies. By analyzing skin samples and genetic information, the research seeks to uncover the underlying mechanisms of these conditions and improve treatment options. Patients may participate in clinical trials that explore new therapies and better understand their skin condition.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for individuals suffering from atopic dermatitis.
How similar studies have gone: Previous research has shown promise in understanding atopic dermatitis through genetic and clinical evaluations, indicating that this approach has potential for success.
Where this research is happening
-
National Jewish Health
Denver, United States Active
Researchers
- Principal investigator: Leung, Donald Ym — National Jewish Health
- Study coordinator: Leung, Donald Ym
Related research
Other NIH-funded projects on the same topics.
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Stopping Atopic Dermatitis and Allergy: Preventing Food Allergy by Protecting the Skin
A large study in infants at high risk for allergies tests whether using a skin barrier cream together with early, proactive skin care can prevent peanut allergy and other food allergies.
-
SEAL Study: Preventing peanut allergy by protecting baby skin
This trial tests whether using a skin-emollient and proactive skin steroids early in life can prevent peanut allergy in high-risk infants.
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SEAL Study: Prevent allergy by protecting the baby’s skin
A very young group of high-risk babies will try a early skin-care plan to reduce eczema and prevent peanut allergy.
-
Understanding how skin fungi affect atopic dermatitis in adults
A study will look at how the skin's fungal community influences atopic dermatitis in adults and whether this understanding could lead to new treatments.
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Preventing eczema-related allergies by strengthening infants' skin barrier
This project will see if using a trilipid skin cream plus proactive mild topical steroids in infants with early dry skin or eczema lowers their chances of developing food allergies.
-
Personalized predictions for how atopic dermatitis may progress in kids and teens
A patient-friendly plan to forecast how early-onset eczema might evolve in children and young people using simple health clues and data from diverse settings.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.