Understanding the factors influencing chronic inflammatory skin diseases
Official title: Determinants of Chronic Inflammatory Skin Disease Trajectories
Run by University Hospital Schleswig-Holstein · NCT05928169 · Data updated 2026-11-12
This study is trying to understand what causes different types of chronic skin conditions, like eczema and psoriasis, to behave differently in patients over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 0 Years to 80 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University Hospital Schleswig-Holstein Academic / other |
| Drugs / interventions | dupilumab, tralokinumab |
| Locations | 1 site (Kiel) |
| Status | Recruiting |
| Started | May 1, 2023 |
| Main results expected | April 30, 2032 |
| Study ends | December 31, 2032 |
| Registry record updated | August 28, 2026 |
| Trial ID | NCT05928169 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with inflammatory skin diseases by a dermatologist who can provide informed consent.
✕Probably not a fit
Patients who are pregnant, breastfeeding, or currently participating in another clinical trial may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the variability in clinical expression and progression of chronic inflammatory skin diseases such as atopic dermatitis, psoriasis, eczema, lichen, and alopecia areata. By conducting long-term clinical assessments and analyzing individual biomaterials, the study seeks to identify clinical and molecular factors that correlate with disease subtypes and progression. The research will involve a larger cohort of patients to confirm preliminary findings from pilot studies regarding disease heterogeneity and its underlying mechanisms.
Why it matters
Potential benefit: If successful, this study could lead to improved patient management and personalized treatment strategies for chronic inflammatory skin diseases.
How similar studies have gone: Preliminary pilot studies have suggested potential success in identifying disease subtypes, but this study aims to confirm and expand upon those findings in a larger cohort.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * dermatologist-diagnosed inflammatory skin disease * informed consent Exclusion Criteria: * subject and/or the legal guardians are not able to give written informed consent * pregnant and breastfeeding women * concurrent participation in a clinical trial * use of systemic immunosuppressive therapy or phototherapy during the last 4 weeks or receipt of biologics therapy (e.g. dupilumab, tralokinumab) within the last 3 months * treatment of the target skin areas with topical corticosteroids, calcineurin inhibitors or emollients 24 hours before sample collection
Where it's running
-
Department of Dermatology and Allergy, University Hospital Schleswig-Holstein
Kiel, Germany Recruiting
Study contacts
- Study coordinator: Stephan Weidinger, MD
- Email: sweidinger@dermatology.uni-kiel.de
- Phone: 0049431500
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.