Clinical trial Recruiting at 1 site Observational Ages 0 to 80

Understanding the factors influencing chronic inflammatory skin diseases

Official title: Determinants of Chronic Inflammatory Skin Disease Trajectories

Run by University Hospital Schleswig-Holstein · NCT05928169 · Data updated 2026-11-12

This study is trying to understand what causes different types of chronic skin conditions, like eczema and psoriasis, to behave differently in patients over time.

More Atopic Dermatitis trials

Quick facts

Study typeObservational
Ages0 Years to 80 Years
SexAll
Enrollment1000 (estimated)
SponsorUniversity Hospital Schleswig-Holstein
Academic / other
Drugs / interventionsdupilumab, tralokinumab
Locations1 site (Kiel)
StatusRecruiting
StartedMay 1, 2023
Main results expectedApril 30, 2032
Study endsDecember 31, 2032
Registry record updatedAugust 28, 2026
Trial IDNCT05928169 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals diagnosed with inflammatory skin diseases by a dermatologist who can provide informed consent.

Probably not a fit

Patients who are pregnant, breastfeeding, or currently participating in another clinical trial may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the variability in clinical expression and progression of chronic inflammatory skin diseases such as atopic dermatitis, psoriasis, eczema, lichen, and alopecia areata. By conducting long-term clinical assessments and analyzing individual biomaterials, the study seeks to identify clinical and molecular factors that correlate with disease subtypes and progression. The research will involve a larger cohort of patients to confirm preliminary findings from pilot studies regarding disease heterogeneity and its underlying mechanisms.

Why it matters

Potential benefit: If successful, this study could lead to improved patient management and personalized treatment strategies for chronic inflammatory skin diseases.

How similar studies have gone: Preliminary pilot studies have suggested potential success in identifying disease subtypes, but this study aims to confirm and expand upon those findings in a larger cohort.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* dermatologist-diagnosed inflammatory skin disease
* informed consent

Exclusion Criteria:

* subject and/or the legal guardians are not able to give written informed consent
* pregnant and breastfeeding women
* concurrent participation in a clinical trial
* use of systemic immunosuppressive therapy or phototherapy during the last 4 weeks or receipt of biologics therapy (e.g. dupilumab, tralokinumab) within the last 3 months
* treatment of the target skin areas with topical corticosteroids, calcineurin inhibitors or emollients 24 hours before sample collection

Where it's running

  • Department of Dermatology and Allergy, University Hospital Schleswig-Holstein
    Kiel, Germany
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.