Coordinating national research on atopic dermatitis (eczema)
Official title: ATOPIC DERMATITIS RESEARCH NETWORK LEADERSHIP CENTER
Funded at National Jewish Health · NIH-11314555 · Data updated 2026-11-12
A national effort that brings researchers together to better understand different types of eczema and speed development of more targeted treatments for people with atopic dermatitis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project start | April 9, 2020 |
| Project end | March 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $4,361,109 |
| NIH project number | 5UM1AI151958-07 |
| Project ID | NIH-11314555 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are people with atopic dermatitis (eczema) of any age or severity who can attend research visits, provide skin or swab samples, and may be willing to join clinical trials.
✕Less likely to help
People without atopic dermatitis, those unable to travel to study sites, or those expecting guaranteed immediate improvement may not receive direct benefit from participation.
What this research studies
This project runs a leadership center that coordinates a network of clinical research sites studying atopic dermatitis (eczema). The team supports multi-site studies and trials that collect skin samples, microbiome swabs, and immune measurements from people with different eczema patterns. Researchers compare skin barrier function, microbes on the skin, and local immune responses to define distinct disease subtypes and identify new treatment targets. By organizing large, coordinated studies, the network aims to help match the right therapies to the right patients.
Why it matters
Potential benefit: Could lead to more personalized eczema treatments that target the specific skin barrier, microbial, or immune problems driving each person's symptoms.
How similar studies have gone: Previous clinical research has produced effective type 2–targeting treatments (for example, dupilumab), and this network builds on those successes to identify additional subtypes and targets.
Where this research is happening
-
National Jewish Health
Denver, United States Active
Researchers
- Principal investigator: Leung, Donald Ym — National Jewish Health
- Study coordinator: Leung, Donald Ym
Related research
Other NIH-funded projects on the same topics.
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Stopping Atopic Dermatitis and Allergy: Preventing Food Allergy by Protecting the Skin
A large study in infants at high risk for allergies tests whether using a skin barrier cream together with early, proactive skin care can prevent peanut allergy and other food allergies.
-
SEAL Study: Preventing peanut allergy by protecting baby skin
This trial tests whether using a skin-emollient and proactive skin steroids early in life can prevent peanut allergy in high-risk infants.
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SEAL Study: Prevent allergy by protecting the baby’s skin
A very young group of high-risk babies will try a early skin-care plan to reduce eczema and prevent peanut allergy.
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Understanding how skin fungi affect atopic dermatitis in adults
A study will look at how the skin's fungal community influences atopic dermatitis in adults and whether this understanding could lead to new treatments.
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Preventing eczema-related allergies by strengthening infants' skin barrier
This project will see if using a trilipid skin cream plus proactive mild topical steroids in infants with early dry skin or eczema lowers their chances of developing food allergies.
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Personalized predictions for how atopic dermatitis may progress in kids and teens
A patient-friendly plan to forecast how early-onset eczema might evolve in children and young people using simple health clues and data from diverse settings.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.