Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

PALLAS 311 nm UVB laser treatment for vitiligo, psoriasis, alopecia areata, and atopic dermatitis

Official title: Study of the Effectiveness of the PALLAS Laser in the Treatment of Skin Diseases That Respond Well to UV Light

Run by Szeged University · NCT07250997 · Data updated 2026-11-12

This study will test the PALLAS 311 nm UVB laser as an in-clinic, twice-weekly treatment for adults with vitiligo, psoriasis, alopecia areata, or atopic dermatitis for up to three months.

More Atopic Dermatitis trials

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment50 (estimated)
SponsorSzeged University
Academic / other
Locations1 site (Szeged, Csongrád-Csanád Vármegye)
StatusRecruiting
StartedDecember 10, 2025
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedFebruary 6, 2026
Trial IDNCT07250997 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with vitiligo, psoriasis, alopecia areata, or atopic dermatitis that is expected to respond to targeted UVB, who can attend twice-weekly clinic visits and provide informed consent.

Probably not a fit

Patients under 18, pregnant people, those with epilepsy, active infections or fever, or skin disease unlikely to respond to targeted UVB are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, prospective clinical evaluation of the CE-marked PALLAS 311 nm solid-state UVB laser used on skin areas such as the face, hands, arms, feet, or legs. Adult patients with skin conditions expected to respond to targeted UVB will receive two approximately 10-minute laser sessions per week for up to three months, with photographic documentation at baseline and monthly. Investigators will record clinical responses and patients will complete a Patient Satisfaction Scale at study end, while also providing feedback on the device's user-friendliness. The study excludes minors, pregnant people, those with epilepsy, active infection or fever, and participants currently in other trials.

Why it matters

Potential benefit: If successful, the PALLAS laser could offer a stable, effective, low-maintenance localized UVB option that shortens treatment sessions and reduces the risk of unpredictable dosing or burns.

How similar studies have gone: Targeted 311 nm UVB and excimer laser treatments have shown benefit for these conditions in prior studies, while the PALLAS device itself represents a newer implementation of that approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. The subject understands the information provided, gives informed consent to participate in the study and is deemed by the investigator to be able to participate,
2. a skin condition that is expected to respond well to targeted UVB treatment,
3. a signed consent form.

Exclusion Criteria:

1. Patient under 18 years of age,
2. pregnancy
3. epilepsy,
4. fever, infectious diseases,
5. the patient is within one month or currently enrolled in another clinical trial.

Where it's running

  • University of Szeged, Albert Szent-Györgyi Clinical Centre, Department of Dermatology and Allergology
    Szeged, Csongrád-Csanád Vármegye, Hungary
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.