PALLAS 311 nm UVB laser treatment for vitiligo, psoriasis, alopecia areata, and atopic dermatitis
Official title: Study of the Effectiveness of the PALLAS Laser in the Treatment of Skin Diseases That Respond Well to UV Light
Run by Szeged University · NCT07250997 · Data updated 2026-11-12
This study will test the PALLAS 311 nm UVB laser as an in-clinic, twice-weekly treatment for adults with vitiligo, psoriasis, alopecia areata, or atopic dermatitis for up to three months.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Szeged University Academic / other |
| Locations | 1 site (Szeged, Csongrád-Csanád Vármegye) |
| Status | Recruiting |
| Started | December 10, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | February 6, 2026 |
| Trial ID | NCT07250997 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with vitiligo, psoriasis, alopecia areata, or atopic dermatitis that is expected to respond to targeted UVB, who can attend twice-weekly clinic visits and provide informed consent.
✕Probably not a fit
Patients under 18, pregnant people, those with epilepsy, active infections or fever, or skin disease unlikely to respond to targeted UVB are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, prospective clinical evaluation of the CE-marked PALLAS 311 nm solid-state UVB laser used on skin areas such as the face, hands, arms, feet, or legs. Adult patients with skin conditions expected to respond to targeted UVB will receive two approximately 10-minute laser sessions per week for up to three months, with photographic documentation at baseline and monthly. Investigators will record clinical responses and patients will complete a Patient Satisfaction Scale at study end, while also providing feedback on the device's user-friendliness. The study excludes minors, pregnant people, those with epilepsy, active infection or fever, and participants currently in other trials.
Why it matters
Potential benefit: If successful, the PALLAS laser could offer a stable, effective, low-maintenance localized UVB option that shortens treatment sessions and reduces the risk of unpredictable dosing or burns.
How similar studies have gone: Targeted 311 nm UVB and excimer laser treatments have shown benefit for these conditions in prior studies, while the PALLAS device itself represents a newer implementation of that approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. The subject understands the information provided, gives informed consent to participate in the study and is deemed by the investigator to be able to participate, 2. a skin condition that is expected to respond well to targeted UVB treatment, 3. a signed consent form. Exclusion Criteria: 1. Patient under 18 years of age, 2. pregnancy 3. epilepsy, 4. fever, infectious diseases, 5. the patient is within one month or currently enrolled in another clinical trial.
Where it's running
-
University of Szeged, Albert Szent-Györgyi Clinical Centre, Department of Dermatology and Allergology
Szeged, Csongrád-Csanád Vármegye, Hungary Recruiting
Study contacts
- Study coordinator: Lajos Kemény, professor, MD, DSc, MHAS
- Email: kemeny.lajos@med.u-szeged.hu
- Phone: +36305152884
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.