Condition

Atopic Dermatitis (AD) clinical trials and research

• 21Clinical trials
• 2NIH research projects
• 2New in 30 days
• 15Countries

Newest Atopic Dermatitis (AD) clinical trials

All recruiting trials (21)

• Roflumilast Cream 0.3% for moderate to severe atopic dermatitis in children, adolescents, and adults

  A cream called roflumilast 0.3% is tested once daily to see if it helps people with moderate to severe atopic dermatitis, compared to a non-medicated cream, across ages 6 and up.

  Recruiting at 4 sites Phase 3 Arcutis Biotherapeutics, Inc. · Birmingham, Alabama and 3 other locations · NCT07916480

• LT-002-158 tablets for moderate-to-severe atopic dermatitis in adults

  This study tests LT-002-158 vs placebo to see if it helps adults with moderate-to-severe atopic dermatitis.

  Recruiting Phase 2 Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. · Hangzhou, Zhejiang · NCT07895615

• PRA-216 for moderate to severe atopic dermatitis: safety and how it works in the body

  This study tests PRA-216 versus placebo to see if it is safe and helps people with moderate to severe atopic dermatitis.

  Recruiting at 6 sites Phase 2 Prana Therapies Inc · Botany, New South Wales and 8 other locations · NCT07810777

• Skin structure in atopic dermatitis patients treated with nemolizumab assessed by reflectance confocal microscopy

  This study tests whether nemolizumab changes skin structure in adults with moderate-to-severe atopic dermatitis using a noninvasive imaging method.

  Recruiting Hôpitaux Drôme Nord · Romans-sur-Isère, Drôme · NCT07730788

• Global Health Look at Atopic Dermatitis

  A worldwide, multicenter study tests how people with atopic dermatitis access care and treat it, using data from routine medical records.

  Recruiting University of Zurich · Zurich · NCT07659756

• Stapokibart Injection for atopic dermatitis in adults

  This study tests Stapokibart Injection in adults with atopic dermatitis to see how safe it is and whether it helps.

  Recruiting Chengdu Kangnuoxing Biopharma,Inc. · Beijing, Beijing Municipality · NCT07544862

• S-4321 in adults with autoimmune or immune-mediated diseases

  This study tests S-4321 in adults with autoimmune conditions to see if it is safe and tolerable and to gather early data on how the drug behaves in the body and its initial effects on disease markers.

  Recruiting at 2 sites Phase 1 Seismic Therapeutic AU Pty Ltd · Charlestown, New South Wales and 1 other locations · NCT07455578

• ARQ-234 single and multiple rising dose testing

  This will test different single and repeated doses of ARQ-234 to see if they are safe and how the drug behaves in healthy adults and adults with moderate-to-severe atopic dermatitis.

  Recruiting at 7 sites Phase 1 Arcutis Biotherapeutics, Inc. · Miami, Florida and 6 other locations · NCT07453602

• GS101 Injection vs Dupixent for moderate-to-severe atopic dermatitis

  This trial tests whether GS101 injections can help adults with moderate-to-severe atopic dermatitis as good as Dupixent®.

  Recruiting Phase 3 Jiangsu Genscend Biopharmaceutical Co., Ltd · Shenyang, Liaoning · NCT07386743

• When IgE autoantibodies appear in newborns at risk for atopic dermatitis

  This study will test whether newborns with a family history of allergy already have self-reactive IgE antibodies at birth and whether those antibodies link to later atopic eczema.

  Recruiting Universitair Ziekenhuis Brussel · Jette, Brussels Capital · NCT07316465

• ENV-294 for adults with moderate-to-severe atopic dermatitis

  This trial tests whether taking ENV-294 daily for 12 weeks reduces rash and itch in adults with moderate-to-severe atopic dermatitis.

  Recruiting at 32 sites Phase 2 Enveda Therapeutics · Birmingham, Alabama and 31 other locations · NCT07298395

• Emollient cream with a milk-derived peptide for children with mild atopic dermatitis

  This trial will see if an emollient cream containing a milk peptide (glycomacropeptide) can reduce itch, skin signs, and Staphylococcus colonization in children aged 2–12 with mild atopic dermatitis compared with a regular emollient.

  Recruiting Universidad Autónoma de Aguascalientes · Aguascalientes, Aguascalientes · NCT07259343

• Single- and multiple-dose testing of ZL-1503 in adults with moderate to severe atopic dermatitis and healthy volunteers

  This study will test whether single and repeated doses of the investigational drug ZL-1503 are safe and how the body processes them in healthy adults and adults with moderate to severe atopic dermatitis.

  Recruiting at 14 sites Phase 1 Zai Lab (Hong Kong), Ltd. · Woolloongabba, Queensland and 13 other locations · NCT07235384

• Long-term safety and efficacy of CM512 for atopic dermatitis

  This open-label follow-up will test whether continuing CM512 is safe and helps people with atopic dermatitis who finished a parent CM512 study.

  Recruiting Phase 2 Keymed Biosciences Co.Ltd · Beijing, Beijing Municipality · NCT07230483

• CeraVe to restore skin hydration as maintenance for mild-to-moderate atopic dermatitis

  This trial will test whether using CeraVe moisturizing cream as a maintenance treatment keeps skin hydrated in adults with mild-to-moderate atopic dermatitis after steroid-induced clearance.

  Recruiting Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse · Roma, RM · NCT07204561

• SKINERGY: deep biomarker profiling of immune-driven skin diseases in dermatology clinics

  This project will test whether detailed blood, tissue, imaging, and patient-reported biomarker profiles in adults with several immune-related skin conditions can find patterns that distinguish disease types and predict who responds to treatment.

  Recruiting Leiden University Medical Center · Nijmegen, Gelderland and 7 other locations · NCT07021495

• LPX-TI641 safety and body handling in people with atopic dermatitis or psoriasis.

  This trial will test whether taking LPX-TI641 by mouth for 28 days is safe and how the drug behaves in the body for adults with atopic dermatitis or psoriasis.

  Recruiting at 3 sites Phase 1 LAPIX Therapeutics Inc. · Fargo, North Dakota and 2 other locations · NCT06982352

• Evaluating a special formula with synbiotics for infants with atopic dermatitis

  This study is testing a special baby formula with added good bacteria to see if it can help prevent skin allergies in infants who are at risk.

  Recruiting at 19 sites Société des Produits Nestlé (SPN) · Bruges and 24 other locations · NCT06943469

• LT-002-158 tablets in adults with moderate to severe atopic dermatitis

  This study tests LT-002-158 tablets in adults with moderate to severe atopic dermatitis to see if they are safe and help the skin while measuring how the body handles the medicine.

  Recruiting Phase 1/2 Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. · Beijing, Beijing Municipality · NCT06931990

• Testing a new hydrogel for treating mild to moderate eczema

  This study is testing a new hydrogel called zabalafin to see if it helps people with mild to moderate eczema feel better compared to a placebo.

  Recruiting at 12 sites Phase 2 Alphyn Biologics · Brookvale, New South Wales and 11 other locations · NCT06855745

• Herbal ointment for treating atopic dermatitis

  This study is testing a herbal ointment made from a plant to see if it can help people with atopic dermatitis feel better.

  Recruiting Phase 2/3 En Chu Kong Hospital · New Taipei City · NCT06850311

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How genes and skin bacteria affect eczema severity

  This project looks at whether a common gene change and Staphylococcus aureus on the skin make eczema worse in children and adults and whether removing the bacteria helps.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11301854

• Investigating genetic and microbial factors that affect the severity of Atopic Dermatitis.

  This study is looking at how certain genes and skin bacteria might affect how bad Atopic Dermatitis (AD) can get, and it's for people of all ages who have this condition.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11066508

Related topics

Quick answers

How many Atopic Dermatitis (AD) clinical trials are recruiting right now?

21, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in China (6 trials), Australia (4 trials), United States (4 trials), France (2 trials), Belgium (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 1: 4, Phase 3: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →