Understanding and treating genetic issues in overlapping skin conditions like psoriasis and atopic dermatitis
Official title: Defining and treating genetic abnormalities in psoriasis/atopic dermatitis-overlap dermatoses
Funded at University of California, San Francisco · NIH-11133500 · Data updated 2026-11-12
This study is looking at the genetic differences in people who have both psoriasis and atopic dermatitis, to see how these differences can help doctors choose the best treatments for their skin conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | June 20, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $628,968 |
| NIH project number | 1R01AR084006-01A1 |
| Project ID | NIH-11133500 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with psoriasis, atopic dermatitis, or both, who experience ambiguous skin rashes.
✕Less likely to help
Patients with skin conditions that do not overlap with psoriasis or atopic dermatitis may not benefit from this research.
What this research studies
This research aims to identify genetic abnormalities in patients with overlapping symptoms of psoriasis and atopic dermatitis, referred to as PSO-AD rashes. By utilizing advanced biomarkers, the study seeks to understand the underlying causes of these skin conditions and how they respond to specific treatments. Patients will be observed to see if their unique biomarker profiles can predict which targeted therapies will be most effective for them. The ultimate goal is to develop a reliable biomarker that can guide personalized treatment options for individuals suffering from these complex skin disorders.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment plans for patients with overlapping skin conditions.
How similar studies have gone: Previous research has shown promise in using biomarkers for targeted therapies in dermatological conditions, suggesting a potential for success in this novel approach.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Cho, Raymond Jaihyun — University of California, San Francisco
- Study coordinator: Cho, Raymond Jaihyun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.