Sponsor or institution
Clinical trials and research at University of Kentucky
As of November 12, 2026, Find a Trial lists 93 clinical trials run by University of Kentucky that are recruiting, in United States. By phase: Phase 2 (11), Phase 4 (7), Phase 1 (7), Early Phase 1 (5). There are also 637 NIH-funded research projects at this institution, with $366.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 93Clinical trials
- 637NIH research projects
- 1Country
Newest trials
All recruiting trials (93)
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Impact of Osteopathic Manipulative Treatment on Pelvic Floor, Activity, and Gait in Female Runners
This study tests whether osteopathic manipulative treatment helps pelvic floor symptoms, daily activity, and running gait in healthy female runners.
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Radon Risk Messages for Rural Homes
This study tests different radon risk messages to see if they make rural homeowners more likely to test or mitigate radon in their homes.
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Concurrent Immunotherapy and SBRT for Stage IV Cancers
This trial tests whether giving stereotactic body radiation therapy (SBRT) alongside approved immunotherapies can safely help control advanced cancers that have spread, while patients continue their planned treatments.
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Textured insoles to help heel pain and balance in plantar fasciopathy
Researchers will test whether wearing textured insoles can improve walking balance and sensorimotor function in adults with plantar fasciopathy.
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Quality Implementation of Lung Cancer Screening in Kentucky
This project tests how well the QUILS system helps Kentucky lung cancer screening programs work together to screen at-risk residents more effectively.
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Statewide Lung Cancer Screening Improvement in Nevada and Mississippi using the QUILS System
This project tests whether a QUILS-based statewide initiative can expand and sustain high-quality lung cancer screening for people in Mississippi and Nevada.
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Optimizing Additional Therapies With Immune Checkpoint Inhibitors for Solid Tumors
This study tests whether avoiding daily acetaminophen and cannabis products while taking aspirin and loratadine can boost the effectiveness of immune checkpoint therapy for people with solid tumors.
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Fluorescent Probe for Real-Time Kidney Function in Critically Ill Adults
Aging and illness can make kidney tests less reliable, so this study tests a new real-time kidney function device to see if it matches standard methods in critically ill adults.
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Quality Improvement Implementation for Lung Cancer Screening (QUILS) Program Enhancement
This project tests a quality improvement pathway in existing lung cancer screening programs to help identify and prioritize process changes that improve quality and patient retention.
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Cesium-131 brachytherapy to preserve organs in recurrent cervical or endometrial cancer
This study tests whether implanting small cesium-131 seeds can provide targeted radiation to vaginal recurrences of cervical or endometrial cancer in patients who previously had pelvic radiation, with the goal of preserving organs.
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Cobenfy Maintenance to See If It Affects Cocaine Effects in Cocaine Use Disorder
This study tests whether Cobenfy can change how cocaine makes people feel and helps see if it’s safe to use with cocaine in adults with cocaine use disorder.
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Noninvasive spinal cord stimulation to help glucose control in adults with and without spinal cord injury
This study tests whether noninvasive transcutaneous spinal cord stimulation can improve glucose regulation in adults with normal, prediabetic, or type 2 diabetic glucose levels, including people with spinal cord injury.
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STAR Project: Supporting Recovery for People with Criminal Legal System Involvement
A new coaching program tests whether paired Recovery Coach and Loved One Coach sessions help people in recovery from substance use and their supporters see better recovery outcomes.
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Acupuncture vs Sham Acupuncture for Hot Flashes in Prostate Cancer on Hormone Therapy
This study tests whether real acupuncture can reduce hot flashes and improve quality of life in men with prostate cancer who are on hormone therapy.
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Methadone for post-op spine surgery pain control
This trial tests whether giving methadone around the time of spine surgery helps with pain control and lowers opioid needs after surgery for adults.
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Massage therapy feasibility for gynecologic cancer patients during infusion
This study tests whether it's feasible to run a massage therapy program for patients with gynecologic cancer who are receiving infusion treatments.
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Palatal Wound Healing After Free Gingival Graft in Diabetic Patients
This study tests palatal wound healing after a free gingival graft in adults with and without diabetes to see if diabetes affects healing and what factors are linked to outcomes.
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Dental Cleaning to Boost Weight-Loss and Metabolic Health in Obese Children on Semaglutide
This trial tests whether adding dental cleaning to the standard semaglutide treatment helps improve oral health and metabolic outcomes in children with obesity.
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Oral Mucosa Healing After Gum Recession Treatment in Diabetic People
This study tests how gingival recession treatment heals in people with diabetes compared with people without diabetes.
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Repeated CBD to change how cannabis affects mood and pain
This study will test whether taking CBD repeatedly changes the behavioral effects and pain relief experienced by adult cannabis users.
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Noninvasive spinal stimulation to improve walking in hereditary spastic paraplegia
This trial will test whether noninvasive transcutaneous spinal cord stimulation can improve walking and reduce muscle stiffness in adults with hereditary spastic paraplegia.
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10-hour time-restricted eating for people with type 2 diabetes
This trial will try a 10-hour daily eating window for people with type 2 diabetes to see if it improves blood sugar and related health measures over one year.
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Colchicine to lower inflammation and prevent atrial fibrillation after coronary bypass
This trial tests whether giving colchicine to adults having coronary artery bypass (CABG) can lower inflammation and reduce the chance of atrial fibrillation after surgery.
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Therapy Dog Walks to Boost Mobility in Trauma Patients
This study tests whether walking with a certified therapy dog helps adult and pediatric trauma patients move more during a hospital stay.
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Benefits of reducing methamphetamine use
This study will try contingency management to see if cutting back on methamphetamine improves physical, mental, and social health for adults with moderate-to-severe methamphetamine use disorder.
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Recovery of physical function after critical illness in older adults
This study tests how well muscle strength and daily activities improve over 2 years in people aged 40 and older who survived ICU treatment for sepsis or acute lung injury.
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Gamified 6-Minute Walk Test for Children with Neuromuscular Disorders
This study tests whether adding a game to the 6-minute walk test makes kids with neuromuscular disorders enjoy and stay motivated to complete the test.
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How potato amount and form influence vegetable intake in plant-forward meals.
We will test how different amounts and forms of potato in meals affect how much other non-starchy vegetables 18-25 year olds eat and how much they like them.
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Hybrid hospital and community delivery of hepatic artery infusion chemotherapy for liver metastases and intrahepatic cholangiocarcinoma
This Phase 2 trial will test whether giving floxuridine through a surgically implanted hepatic artery infusion pump — with follow-up care either at a major hospital or by local community oncologists — is safe and practical for adults with colorectal cancer liver metastases or unresectable intrahepatic cholangiocarcinom
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Connecting clinics and community partners to address unmet social needs for people with diabetes in rural Kentucky
This project tries a clinic–community program to help adults with diabetes in two rural Kentucky communities get services for unmet social needs.
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Using brain stimulation to reduce impulsive decisions after drinking.
We will test whether two types of noninvasive brain stimulation change decision-making and self-control after drinking in healthy young adults who regularly drink alcohol.
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Home under-mattress monitor to guide mandibular advancement therapy for sleep apnea
This study will test whether a home under-mattress monitor can help set and fine-tune a mandibular advancement device for people with obstructive sleep apnea.
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Women-focused overdose prevention during jail-to-community re-entry in Kentucky
This study tests an overdose prevention package for women leaving jail in rural Kentucky to see if it lowers overdose risk and improves treatment linkage.
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Ankle Muscle Power Program to Help Return to Duty After an Ankle Fracture
This trial tests whether adding ankle muscle power exercises to standard physical therapy helps adults 18–50 recover strength, function, and readiness to return to duty after a surgically fixed ankle fracture.
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Bromelain to reduce facial swelling after jaw surgery
This test will see if taking a daily bromelain supplement before and after orthognathic (jaw) surgery reduces facial swelling and shortens how long swelling lasts in adults.
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Preventing bite changes from mandibular advancement sleep devices with a morning aligner or jaw exercises.
This test compares a removable morning interocclusal aligner to daily jaw exercises to see if they prevent bite changes in adults using mandibular advancement devices for sleep apnea or snoring.
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See if pentoxifylline changes how cocaine affects adults with cocaine use disorder
We will test whether taking pentoxifylline changes how cocaine affects adults with cocaine use disorder who are not currently seeking treatment.
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Brain stimulation for urges in skin-picking and nail-biting.
This study will try transcranial direct current stimulation (tDCS) to see if it reduces urges and how often people pick their skin or bite their nails.
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Troriluzole and methamphetamine response
This study will see if taking troriluzole changes how methamphetamine affects adults with methamphetamine use disorder.
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Reducing heart disease risk in 12–15-year-olds with severe obesity
This will try semaglutide in 12–15-year-olds with class 2–3 obesity to see if it changes weight, heart-related risk markers, body composition, and fitness over about a year.
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Auditory biofeedback gait training for chronic ankle instability
This test will try using sound feedback during walking, rucking, and running to improve gait mechanics and reduce giving-way episodes in physically active adults with chronic ankle instability.
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VK-2019 for adults with relapsed or refractory EBV-positive diffuse large B‑cell lymphoma
This trial tests daily oral VK-2019 in adults with relapsed or refractory EBV-positive DLBCL to see if it is safe and can control the disease.
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Examining interactions between opioids and benzodiazepines
This study tests how the combination of oxycodone and alprazolam affects experienced drug users to see if it leads to more intense effects and potential risks.
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Using tirzepatide before bariatric surgery to improve outcomes
This study is testing if taking tirzepatide before weight loss surgery can help patients recover better and have fewer complications after the surgery.
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Using a patient's own peripheral nerve tissue during DBS to try to help Parkinson's symptoms
This study will test whether placing a patient's own peripheral nerve tissue into either the nucleus basalis of Meynert or the substantia nigra at the time of DBS can help cognitive or motor symptoms in people with Parkinson's disease.
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Implanting nerve tissue into the brain for Parkinson's and Multiple System Atrophy
This study is testing if implanting nerve tissue into the brains of people with early-stage Parkinson's or Multiple System Atrophy can help repair damaged cells and slow down the disease.
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Comparing surgical methods for endometrial cancer
This study is testing two different surgical methods for women with endometrial cancer to see which one helps them stay cancer-free longer after surgery.
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Daily oral cannabis doses for people with cancer
This phase 1 test will give adults with cancer daily oral cannabis or placebo for about four months to see if it helps symptoms like pain, nausea, appetite, sleep, and quality of life.
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Evaluating a new method of spinal cord stimulation for spinal cord injuries
This study is testing a new way of using spinal cord stimulation to see if it is safe and helpful for people with different types of spinal cord injuries.
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Behavioral intervention for chronic jaw pain via telehealth
This study is testing a new online program to help people with chronic jaw pain feel better by teaching them how to manage their pain and comparing it to a regular education program.
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Short-course radiation with chemotherapy for cervical cancer
This trial will test whether a shorter, higher-dose pelvic radiation schedule given with cisplatin and followed by brachytherapy helps women with bulky or limited-metastatic cervical cancer.
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Investigating the effects of Suvorexant on alcohol use
This study is testing if a medication called Suvorexant can help people with Alcohol Use Disorder feel less motivated to drink alcohol.
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A program to improve cancer care coordination and support
This study tests a new program that helps newly diagnosed or recurrent cancer patients get better support and communication with their healthcare teams before they start treatment.
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Surgical treatment for spinal cord injuries using nerve grafts
This study is testing a new surgical method using nerve grafts to see if it can help people with recent spinal cord injuries recover better.
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Cannabis for Obesity: Daily Cannabis vs. Placebo in Adults with Obesity
This study tests whether taking a daily oral cannabis pill for a set period can help weight loss in adults with obesity.
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Effects of exercise on learning and memory in PTSD
This study tests if moderate exercise can help improve learning and memory in adults with PTSD from interpersonal violence to see if it leads to better symptom relief.
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Evaluating telavancin in patients with subarachnoid hemorrhage
This study is testing how well the antibiotic telavancin gets into the spinal fluid of patients with bleeding in the brain to see if it can help treat tough infections.
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Support for mental health and quality of life in advanced lung cancer treatment
This study tests if a new support program can improve mental health and quality of life for people receiving treatment for advanced lung cancer compared to standard care.
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InterTAN dual-screw versus single-screw hip nail to improve recovery after unstable intertrochanteric fracture
This trial will test whether the InterTAN dual-screw hip implant helps people with unstable intertrochanteric hip fractures have less pain and return to walking and normal activity faster than a standard single-screw cephalomedullary nail.
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Reducing suicide risk among sexual and gender diverse young adults in Texas
This study is testing two different suicide prevention programs to see which one helps young adults aged 18-24 from sexual and gender diverse backgrounds in Texas feel safer and reduce their risk of suicide.
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Implementing time-restricted eating for women with mild cognitive impairment
This study is testing if a time-restricted eating plan can help improve brain health in postmenopausal women with mild cognitive impairment.
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Innovative care program for lung cancer survivors
This study is testing a new care program designed to help lung cancer survivors in Kentucky feel better and improve their quality of life compared to standard care.
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Effects of cannabis on opioid withdrawal in individuals with opioid use disorder
This study is testing whether inhaled cannabis can help people with opioid use disorder feel better during withdrawal.
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Efficacy of continuous intercostal nerve block for patients with multiple rib fractures
This study is testing if a continuous intercostal nerve block can provide better pain relief for people with multiple rib fractures compared to standard pain management options.
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Using a mobile app to reduce risky alcohol use and HIV risk
This study is testing a mobile app that sends real-time messages to help people reduce risky drinking and lower their chances of HIV by encouraging safer choices when they visit certain locations.
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Combining immunotherapy and radiation for high-risk prostate cancer
This study is testing if combining an immunotherapy drug with radiation, and possibly adding another medication, can help men with high-risk prostate cancer do better than with standard treatment alone.
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Impact of music on exercise capacity in heart failure patients
This study is testing whether listening to upbeat music can help people with heart failure exercise better and feel more relaxed during their workouts.
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Understanding muscle recovery in ICU survivors
This study looks at how well muscle function and physical abilities recover in people who have survived serious illnesses and spent time in the ICU.
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Collection of biopsy samples to study heart diseases
This study is collecting biopsy samples from patients having heart procedures to see if it can help find new ways to diagnose and treat heart diseases.
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Using imatinib to improve outcomes in gastrointestinal stromal tumors
This study is testing if monitoring imatinib levels can help improve the quality of life for people with gastrointestinal stromal tumors while reducing side effects.
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Analysis of patients with spinal epidural abscess
This study looks at around 200 patients treated for spinal epidural abscesses to see how their medical history and other factors affect their treatment and recovery.
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Creating a repository for patients with degenerative cervical myelopathy
This study is creating a database of people with degenerative cervical myelopathy and others with similar spinal issues to see how their symptoms progress and how well different treatments work.
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Using Glyburide to protect the spinal cord after injury
This study is testing if giving the medication Glyburide soon after a spinal cord injury can help improve recovery for adults aged 18 to 80.
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Genotype-guided dosing for cancer treatment
This study is testing if giving cancer patients a personalized dose of irinotecan based on their genetics can lead to better treatment results than the usual dosing method.
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Data collection for patients undergoing lumbar spinal fusion with Implanet Jazz System
This study is collecting information from patients who have had back surgery using the Implanet Jazz System to see how well the device works over time.
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Evaluation of pathways for preventing preterm birth
This study is trying to find ways to prevent preterm birth in pregnant women who are at high risk, while also comparing them to women who are not at risk.
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Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics
This study is testing if the medications mirabegron and tadalafil can help people with prediabetes improve their blood sugar levels over 14 weeks.
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Combining nilotinib with other drugs for treating metastatic melanoma
This study is testing if adding nilotinib to existing treatments can help people with advanced melanoma that has a specific genetic mutation feel better and tolerate the drugs well.
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Time-restricted eating for postmenopausal women with metabolic issues
This study is testing if eating all meals within a 10-hour window can improve metabolic health in postmenopausal women who have metabolic issues.
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Wearable fluorescence imaging for brain tumor surgery
This study is testing a new wearable device that uses special light to help surgeons find brain tumors during surgery, comparing it to a traditional microscope to see if it works just as well.
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Comparing flat dose and weight-based chemotherapy for peritoneal carcinomatosis
This study is testing whether giving a flat dose or a dose based on body weight of a chemotherapy drug can help people with certain cancers that have spread to the abdominal area do better after surgery.
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Effects of Mirabegron on Beige Fat Activation in Prediabetic Patients
This study is testing if the drug mirabegron can help people with prediabetes by activating a type of fat that may improve their blood sugar levels and overall metabolism.
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Helping individuals recover from trauma and PTSD
This study is testing two different therapies to see which one helps people with PTSD from sexual trauma feel better.
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Montelukast for protecting cartilage after ACL surgery
This study is testing if taking montelukast for six months after ACL surgery can help older patients reduce inflammation and protect their cartilage from damage.
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Improving recovery from patellar instability with blood flow restriction training
This study is testing if adding blood flow restriction training to regular physical therapy can help people recover faster and get stronger after knee injuries caused by patellar instability.
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Screening for ovarian cancer using transvaginal ultrasound
This study is testing if regular transvaginal ultrasounds can help women at higher risk for ovarian cancer catch it earlier and improve their chances of survival.
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A program to improve health choices for rural Appalachians
This study is testing a new program that uses a mobile app and coaching to help adults in rural Appalachia eat healthier and be more active.
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Improving awareness of low blood sugar in diabetes with metoclopramide
This study is testing if the medication metoclopramide can help people with Type 1 Diabetes who can't sense low blood sugar to become more aware of it and reduce their risk of hypoglycemia.
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Investigating the role of amylin in diabetic nerve damage
This study is trying to see if the levels of a hormone called amylin are linked to nerve damage in people with Type-2 diabetes.
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Comparing Envarsus XR® and Tacrolimus for Kidney Transplant Patients
This study is testing whether a new kidney medication called Envarsus XR® is safer and more effective than the standard medication tacrolimus for people getting a kidney transplant.
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Registry for blood and tissue samples from stroke patients
This study is collecting blood and tissue samples from stroke patients to see if they can find clues that help understand stroke better and lead to new treatments.
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Evaluating genomic testing for cancer treatment outcomes
This study tests if using genetic information to choose cancer treatments can help patients with hard-to-treat metastatic cancer live longer without their disease getting worse.
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Cardiovascular Biorepository: Using patient and donor samples to study heart disease
This biorepository collects biospecimens from adults undergoing cardiovascular procedures and from organ donors to help researchers understand heart disease and its treatments.
NIH-funded research (newest 40 of 637)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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East Palestine health impact study following train derailment
A community-engaged study in East Palestine will follow residents to understand health symptoms, exposure markers, and air quality after a major train derailment.
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Grade C Periodontitis in Young People: Genetic Clues to a Severe, Early Condition
A research team is studying why some young people develop a severe form of gum disease called Grade C periodontitis and how genetics and bacteria like Aa may contribute.
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Regulation of exon junction complex in cancer biology
This grant studies how a key molecular complex that controls RNA processing acts in cancer, with the aim of understanding how it contributes to cancer cell behavior.
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Alcohol use and suicidal thoughts: how decision-making affects risk
This project looks at how acute alcohol use and people’s decision-making patterns relate to suicidal thoughts and behaviors in adults.
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Kentucky workplace health surveillance program improving safety for workers
A national institute-funded program is supporting Kentucky to monitor and improve safety and health at work for better protection of workers.
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Gabapentin use in older adults and related health outcomes
This project will look at how gabapentin is used by older adults and whether that use is linked to health outcomes using Medicare data.
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Metabolic clues to recovery after mild traumatic brain injury
This grant tests how a brain injury affects metabolism and whether promoting certain metabolic pathways helps recovery, using rodent and cellular models related to concussion.
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Overcoming obesity-related resistance to immunotherapy in kidney cancer
A study aims to understand why obesity affects how well immunotherapy works for people with advanced kidney cancer and how to improve treatments for those patients.
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PAQR4's role in pancreatic beta cell function and type 2 diabetes
A patient-focused look at how PAQR4 may affect insulin secretion and blood sugar control in adults with type 2 diabetes.
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Objective lung-donor quality tools to expand the transplant pool
A lung-transplant-focused project aims to use gene-based risk tools to better judge donor organs and prevent recipient lung dysfunction.
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Genetic causes of age-related TDP-43 changes and mixed dementia
This project looks for gene differences that help explain why older adults develop TDP-43–related and mixed dementias.
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Biomarkers to track how well interventions delay dementia in people at risk
This grant tests whether biomarker changes and brain imaging can show if a health plan combining vascular risk reduction and aerobic exercise can delay dementia in adults 21 and older.
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Opioid Use Disorder County Prevalence Using Recapture Estimates (OUD CAPTURE)
Aimed at estimating how common opioid use disorder is across counties using advanced statistical methods to help target treatment and resources.
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Genetics of TDP-43 and mixed-path dementia in older adults
This project looks at genes that may raise or lower the risk of TDP-43-related and mixed-path dementia in older adults.
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Kentucky Health Kiosk: Linking Rural Appalachia to HIV, overdose, and infection services
A community-led project tests a discreet, 24/7 health kiosk in rural Appalachian Kentucky to help people access HIV, overdose, HCV, and infection prevention services.
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POPI: Placenta, Opioids and Perinatal Implications
This grant supports research into how maternal opioid use affects placenta function and baby brain development, with a focus on people in Appalachia and potential long-term neurobehavioral outcomes.
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Multiscale microgels delivering GDNF and agrin to help with sarcopenia
Aimed at older adults with muscle loss, this project tests a new treatment that slowly releases biological factors to support nerve-muscle connections and improve strength when combined with or for people who can’t do intense resistance training.
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Population-level alcohol screening and support for cancer patients to reduce secondary cancer risk
A large study will test a practical program in cancer care to screen for hazardous drinking and connect patients to help, aiming to lower the chance of cancer coming back or new cancers.
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PACAP’s role in brain circuits during alcohol abstinence (BNST)
Aims to understand how a brain chemical called PACAP affects communication in the amygdala region during alcohol abstinence, with attention to differences between men and women.
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Systematic look at how THC and CBD interact in real people
A study at the University of Kentucky will test how THC and CBD work together across different doses to see if they affect driving skills, reward and safety, and how the body processes them.
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Baculovirus-based therapy to treat head and neck cancer with a gentle, minimally invasive approach
A new, minimally invasive approach using baculovirus-delivered CRISPR gene editing aims to treat head and neck squamous cell carcinoma while aiming to preserve essential tissues.
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AI-powered cancer data extraction improves accuracy in cancer registries
A research project aims to make cancer registry reports faster and more reliable by improving an AI system that automatically reads pathology reports to classify cancer information.
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Target PAQR4-Ceramide-GPNMB Pathway in MASH (liver disease)
A patient-centered look at how a liver disease pathway involving PAQR4, ceramides, and GPNMB might lead to better biomarkers and therapies for MASLD and MASH.
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Base Editing APOE4 for Alzheimer's Disease
AIM: test a gene-editing approach that could reduce Alzheimer's risk by correcting APOE4 to a more protective form in a way that might be used in people at risk.
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INSPIRED: Faster, easier referrals and engagement in diabetes self-management education
A Kentucky study is testing ways to get more people with diabetes referred to and participating in diabetes self-management education and support.
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Accelerated TMS for Cocaine Use Disorder
A new, faster brain-stimulation treatment is being tested to help adults with cocaine use disorder reduce cravings and use.
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MedSMA℞T Families in Emergency Departments: A digital game to prevent opioid misuse in teens and families
A short, engaging digital game-based program used in emergency departments to help teens and their families learn safer opioid use and reduce misuse.
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Kentucky Center for Clinical & Translational Science supports faster, smarter health research
This grant supports Kentucky's CTSA hub to speed up health research and bring new findings into communities, especially rural areas, using data, collaboration, and practical methods.
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Cross-protection between chikungunya vaccine and Mayaro virus
A vaccine already approved for chikungunya may also help protect against the related Mayaro virus, and researchers will study how antibodies and other immune responses could provide that cross-protection.
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Strengthening AMR surveillance in Kentucky retail meat with NARMS
This project aims to track antibiotic-resistant bacteria in raw retail meats across Kentucky to better protect public health.
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Reducing Methamphetamine Use to Improve Health and Well-Being
A clinical trial tests whether giving incentives to people with methamphetamine use disorder helps them use less meth and improves heart, immune, sleep, and psychosocial health.
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Moringa in Breastfeeding: A mom-and-baby study
This trial tests whether adding moringa leaf powder to mothers’ diets can increase breast milk volume and improve infant growth among undernourished families in Kenya.
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PTP1b Inhibition to Boost Anti-Tumor Response During Chemotherapy in Advanced Breast Cancer
Aims to see if blocking a cellular protein called PTP1b can improve the body’s immune response against breast cancer when patients receive chemotherapy.
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University of Kentucky SuRE Resource Center
A center helps partner institutions prepare and submit NIH grant applications, focusing on SuRE and SuRE-First awards, to boost their research programs.
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Targeting NINJ1 to Prevent Blood Clots Linked to Inflammation
A study exploring how a specific cell-death process in immune cells worsens clotting during infections and how blocking it could reduce dangerous blood clots.
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RNA changes that drive harmful circRNA proteins in Alzheimer’s disease
This NIH grant explores how chemical changes to circRNAs in the brain may create proteins that worsen Alzheimer’s disease.
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Kentucky Women’s Justice Network to Prevent Overdose in Rural Communities
This grant tests new ways to cut overdose deaths among women involved with the criminal-legal system as they leave jail and re-enter rural Kentucky communities.
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Sex and state–dependent brain circuits that control parental behavior
A study of how sex and physical state shape the brain circuits that drive parenting, with findings that could help understand why parental care varies and how it might be supported.
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Role of DENND5B in How the Body Absorbs Dietary Lipids
A study in adults looking at how a specific gene, DENND5B, affects how our intestines absorb fats from meals and how this influences heart health.
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Muscle-fat cell communication via tiny vesicles in people with prediabetes or diabetes
A study to understand how tiny particles released by muscles interact with fat tissue in adults with prediabetes or type 2 diabetes.
Quick answers
How many clinical trials run by University of Kentucky are recruiting right now?
93, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 11, Phase 4: 7, Phase 1: 7, Early Phase 1: 5. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.