Implementing time-restricted eating for women with mild cognitive impairment
Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment
This study is testing if a time-restricted eating plan can help improve brain health in postmenopausal women with mild cognitive impairment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 45 Years to 95 Years |
| Sex | Female |
| Sponsor | University of Kentucky Academic / other |
| Locations | 1 site (Lexington, Kentucky) |
| Trial ID | NCT05858008 on ClinicalTrials.gov |
What this trial studies
This study investigates the feasibility of a time-restricted eating (TRE) intervention specifically for postmenopausal women aged 45-95 diagnosed with mild cognitive impairment. Over a 10-week period, participants will undergo baseline assessments followed by an 8-week TRE intervention where they will consume all daily calories within a self-selected 10-hour window. Data on metabolic health, activity, sleep, and cognitive function will be collected to evaluate the impact of TRE on cognitive impairment. The study aims to provide insights into a potential therapeutic approach for improving cognitive health in women at risk for Alzheimer's disease.
Who should consider this trial
Good fit: Ideal candidates are postmenopausal women aged 45-95 with a diagnosis of mild cognitive impairment.
Not a fit: Patients with conditions that may interfere with eating behaviors, such as significant circadian disruption or clinical eating disorders, may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could help improve cognitive function and delay the onset of Alzheimer's disease in women with mild cognitive impairment.
How similar studies have performed: While the approach of time-restricted eating is gaining interest, this specific application in women with mild cognitive impairment is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Postmenopausal Women * Age 45-95 * Diagnosis of mild cognitive impairment Exclusion Criteria: * Individuals prone to hypoglycemia * Liver disease * Taking medications that affect eating behaviors * Alcohol consumption of \>2 drinks per day * Significant circadian disruption * Having care-taking responsibilities that significantly affect sleep * Shift work or irregular lifestyle * Diagnosed clinical eating disorder * Participating in a formal weight loss program
Where this trial is running
Lexington, Kentucky
- University of Kentucky — Lexington, Kentucky, United States (Recruiting)
Study contacts
- Principal investigator: Julie Pendergast, PhD — University of Kentucky
- Study coordinator: Matt Thomas, PhD
- Email: jmthomg@uky.edu
- Phone: (859) 218-6770
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.