Efficacy of continuous intercostal nerve block for patients with multiple rib fractures
The Efficacy of Continuous Intercostal Nerve Blocks in the Treatment of Patients With Multiple Rib Fractures
This study is testing if a continuous intercostal nerve block can provide better pain relief for people with multiple rib fractures compared to standard pain management options.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 180 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Kentucky Academic / other |
| Locations | 1 site (Lexington, Kentucky) |
| Trial ID | NCT05642026 on ClinicalTrials.gov |
What this trial studies
This interventional study evaluates the effectiveness of continuous intercostal nerve block (CINB) combined with medical therapy compared to standard medical care for patients with multiple rib fractures. It is a prospective, randomized, non-blinded trial that aims to assess pain management outcomes in patients admitted to the trauma service. Participants will receive either CINB with additional pain management or standard treatment involving nonsteroidal anti-inflammatory drugs and opioids. The goal is to determine if CINB provides superior pain relief and improves recovery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with two or more rib fractures who consent to receive continuous nerve block therapy.
Not a fit: Patients with documented allergies to the study medication or those currently using an epidural catheter may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance pain management for patients with multiple rib fractures, potentially reducing reliance on opioids.
How similar studies have performed: Similar studies have shown promising results with nerve block techniques for pain management, suggesting potential efficacy for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects will be at least 18 years old * Subjects will have 2 or more identified rib fractures * Subjects will be willing to provide informed consent for procedure * Subjects will be identified as appropriate for initiation of continuous nerve block therapy for treatment of rib fracture associated pain. Exclusion Criteria: * Documented allergy to study medication * Epidural catheter use * Prisoners * Refusal of CINB therapy
Where this trial is running
Lexington, Kentucky
- University of Kentucky Medical Center — Lexington, Kentucky, United States (Recruiting)
Study contacts
- Principal investigator: Zachary Warriner, MD — University of Kentucky
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.