Creating a repository for patients with degenerative cervical myelopathy
Official title: Development of a Predictive Outcome Model for Patients With Degenerative Cervical Myelopathy Using Objective Functional and Biological Measures.
Run by University of Kentucky · NCT05446259 · Data updated 2026-11-12
This study is creating a database of people with degenerative cervical myelopathy and others with similar spinal issues to see how their symptoms progress and how well different treatments work.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 245 (estimated) |
| Sponsor | University of Kentucky Academic / other |
| Locations | 1 site (Lexington, Kentucky) |
| Status | Recruiting |
| Started | July 13, 2022 |
| Main results expected | June 2027 |
| Study ends | May 2028 |
| Registry record updated | February 13, 2026 |
| Trial ID | NCT05446259 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with degenerative cervical myelopathy or cervical degenerative disease without myelopathy.
✕Probably not a fit
Patients who do not meet the diagnostic criteria for degenerative cervical myelopathy or cervical degenerative disease will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to establish a research repository that includes patients diagnosed with degenerative cervical myelopathy (DCM) alongside a control group of individuals with non-myelopathic spinal disease. The repository will facilitate the assessment of functional and biological measures to enhance the prediction of symptom progression and treatment responses in DCM patients. Additionally, it will be utilized to develop a risk assessment scale for predicting functional outcomes after surgical management of DCM.
Why it matters
Potential benefit: If successful, this study could lead to improved prediction of disease progression and treatment responses for patients with degenerative cervical myelopathy.
How similar studies have gone: While this approach is observational and may not have been extensively tested in this specific context, similar studies have shown promise in utilizing patient repositories for improving clinical outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of degenerative cervical myelopathy * Diagnosis of cervical degenerative disease without myelopathy Exclusion Criteria: * None outside or diagnostic requirements and age limits.
Where it's running
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University of Kentucky
Lexington, Kentucky, United States Recruiting
Study contacts
- Principal investigator: Francis Farhadi, MD, PhD — University of Kentucky
- Study coordinator: Francis Farhadi, MD, PhD
- Email: francis.farhadi@uky.edu
- Phone: 859-562-0247
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Timing of Rehabilitation After Cervical Spine Surgery in Degenerative Myelopathy
This study tests whether starting physical therapy two weeks after cervical spine surgery helps people with degenerative cervical myelopathy recover better than starting at six weeks.
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Cervical spinal cord stimulation for improving arm and hand function
This study is testing different ways of using spinal cord stimulation to see if it can help people with cervical spinal cord injuries improve their arm and hand function.
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Evaluating a new method of spinal cord stimulation for spinal cord injuries
This study is testing a new way of using spinal cord stimulation to see if it is safe and helpful for people with different types of spinal cord injuries.
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Assessing Proprioceptive Deficits in Degenerative Cervical Myelopathy
This study is trying to see if a new test can help find balance problems in people over 45 with degenerative cervical myelopathy, to catch issues early and prevent serious disabilities.
-
Improving hand function after spinal cord injury using electrical stimulation
This study is testing if a new way of using electrical stimulation on the brain and spinal cord can help people with cervical spinal cord injuries regain better control and movement in their arms and hands.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.