Quality Improvement Implementation for Lung Cancer Screening (QUILS) Program Enhancement
Official title: Statewide Optimization of Lung Cancer Screening Utilizing the QUILS System
Run by University of Kentucky · NCT07639255 · Data updated 2026-11-12
This project tests a quality improvement pathway in existing lung cancer screening programs to help identify and prioritize process changes that improve quality and patient retention.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 330 (estimated) |
| Sponsor | University of Kentucky Academic / other |
| Locations | 17 sites (Ashland, Kentucky and 16 other locations) |
| Status | Recruiting |
| Started | April 1, 2025 |
| Main results expected | June 1, 2027 |
| Study ends | June 1, 2028 |
| Registry record updated | July 1, 2026 |
| Trial ID | NCT07639255 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are lung cancer screening programs and their staff (physicians, nurses, administrators, and other personnel) willing to participate in the QUILS assessment, feedback, and formative evaluations.
✕Probably not a fit
Program staff who are unwilling to participate in assessments, feedback sessions, or interviews may not experience benefits from the optimization activities.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The initiative audits participating lung cancer screening programs to assess elements linked with higher quality and better patient retention. A feedback report is generated to highlight priorities for process improvement. Programs receive the QUILS System and participate in index assessments, audit feedback presentations, and formative interviews to understand how to optimize screening workflows. The study focuses on optimization rather than a new medical treatment, using structured feedback and evaluation to drive improvements. It is implemented across several Kentucky clinical sites led by Timothy Mullett.
Why it matters
Potential benefit: If successful, programs could streamline workflows, improve patient retention, and enhance the overall quality of the screening process.
How similar studies have gone: Similar quality-improvement implementations in screening programs have shown improvements in process efficiency and retention in other settings, though this exact QUILS approach is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants in Lung Cancer Screening Program, including physicians, nurses, administrators and other staff responsible for the conduct of the program. * Willing to participate in the QUILS Index Assessment Survey process * Willing to participate in the QUILS Audit Feedback presentations Willing to participate in formative evaluation interviews Exclusion Criteria: * Unwilling to participate in the QUILS Index Assessment Survey process * Unwilling to participate in the QUILS Audit Feedback presentations * Unwilling to participate in formative evaluation interviews
Where it's running
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King's Daughter's Medical Center
Ashland, Kentucky, United States Recruiting -
Taylor Regional Hospital
Campbellsville, Kentucky, United States Recruiting -
St. Elizabeth Healthcare
Edgewood, Kentucky, United States Recruiting -
Georgetown Cancer Treatment Cancer
Georgetown, Kentucky, United States Recruiting -
TJ Samson Community Hospital
Glasgow, Kentucky, United States Recruiting -
Hazard Appalachian Regional Healthcare Medical Center
Hazard, Kentucky, United States Recruiting
Show 11 more locations
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Lexington VA Health Care System
Lexington, Kentucky, United States Recruiting -
St. Joseph Health (Catholic Health Initiatives)
Lexington, Kentucky, United States Recruiting -
University of Kentucky Markey Cancer Center
Lexington, Kentucky, United States Recruiting -
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, United States Recruiting -
Meadowview Regional Medical Center
Maysville, Kentucky, United States Recruiting -
Saint Claire Regional Medical Center
Morehead, Kentucky, United States Recruiting -
Rockcastle Regional Hospital
Mount Vernon, Kentucky, United States Recruiting -
Owensboro Health Mitchell Memorial Cancer Center
Owensboro, Kentucky, United States Recruiting -
Mercy Health - Paducah Cancer Center
Paducah, Kentucky, United States Recruiting -
Lake Cumberland Regional Hospital
Somerset, Kentucky, United States Recruiting -
Clark Regional Medical Center
Winchester, Kentucky, United States Recruiting
Study contacts
- Study coordinator: Joseph Alexander, MD
- Email: joseph.alexander@uky.edu
- Phone: 8593230892
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Empowering patients to get lung cancer screening with support and navigation
This pilot study tests a patient navigation and education program to see if it helps adults who are eligible start and complete low-dose CT lung cancer screening.
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Quality Implementation of Lung Cancer Screening in Kentucky
This project tests how well the QUILS system helps Kentucky lung cancer screening programs work together to screen at-risk residents more effectively.
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Statewide Lung Cancer Screening Improvement in Nevada and Mississippi using the QUILS System
This project tests whether a QUILS-based statewide initiative can expand and sustain high-quality lung cancer screening for people in Mississippi and Nevada.
-
Methylation markers from saliva to guide lung cancer screening
This study tests whether DNA methylation patterns in saliva can more accurately identify people who should get a low-dose CT scan for lung cancer screening.
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Multilevel program to increase LDCT lung cancer screening and help African American smokers quit
This program will try combining low-dose CT screening with culturally tailored smoking-cessation support to help African American smokers who are eligible for LDCT quit and get screened.
-
Precision lung cancer screening using AI risk scores and blood biomarkers
This project will test whether the Sybil AI tool and optional blood tests can better predict lung cancer risk for people aged 50–80 getting low-dose CT scans, including those who meet expanded screening rules beyond current USPSTF guidance.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.