Gabapentin use in older adults and related health outcomes
Official title: Gabapentin prescription and health-related outcomes in older adults
Funded at University of Kentucky · NIH-11581607 · Data updated 2026-11-12
This project will look at how gabapentin is used by older adults and whether that use is linked to health outcomes using Medicare data.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project start | December 15, 2023 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $249,000 |
| NIH project number | 4R00AG084892-03 |
| Project ID | NIH-11581607 on NIH RePORTER |
Who could benefit from this research
✓Could help
Older adults (typically 65+ years) with Alzheimer’s disease, dementia, or related conditions who have received or may receive gabapentin.
✕Less likely to help
Patients not using gabapentin or without dementia-related conditions may not directly benefit from this study.
What this research studies
This study uses Medicare claims data linked with Rush Alzheimer’s Center data to map how often older adults start and continue gabapentin, what other medicines they take, and their prior health history. It then estimates how gabapentin prescriptions relate to health outcomes over time in this population with Alzheimer’s disease and related dementias. The goal is to understand real-world effects of gabapentin in older adults to inform safer prescribing. The research will help clinicians weigh potential risks and benefits when considering gabapentin for cognitive or functional symptoms in dementia patients.
Why it matters
Potential benefit: Findings could lead to safer prescribing practices for gabapentin in older adults with Alzheimer’s disease and related dementias.
How similar studies have gone: Prior observational studies have identified patterns in gabapentin use and associated risks, but this project aims to clarify longitudinal outcomes in older adults with dementia.
Where this research is happening
-
University of Kentucky
Lexington, United States Active
Researchers
- Principal investigator: Oh, Gyeon — University of Kentucky
- Study coordinator: Oh, Gyeon
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.