Bromelain to reduce facial swelling after jaw surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults scheduled for orthognathic (jaw) surgery will take a bromelain supplement once daily for nine days total (two days before surgery and seven days after). Participants will keep a log of supplement use and any other medications, and will attend pre- and post-operative clinic visits for measurement and follow-up. The study will measure the amount and duration of facial swelling and collect safety information related to the supplement. Results will be compared across participants to see whether bromelain use is associated with reduced swelling or faster resolution.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* undergoing orthognathic surgery

Exclusion Criteria:

* craniofacial anomalies
* incomplete patient data
* systemic disease that could affect healing
* allergy to latex or pineapple
* under 18 years of age
* non english speaking

Where it's running

• University of Kentucky
  Lexington, Kentucky, United States Recruiting

Study contacts

• Principal investigator: Mohamed Bazina, DDS, MSD — University of Kentucky
• Study coordinator: Emma E Palmer, DMD
• Email: emma.palmer@uky.edu
• Phone: 859-358-6346

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.