Sponsor or institution
Clinical trials and research at Washington University School of Medicine
As of November 12, 2026, Find a Trial lists 218 clinical trials run by Washington University School of Medicine that are recruiting, at sites in 22 countries (most in United States (211), Canada (6), Nigeria (5)). 2 were first registered in the last 30 days. By phase: Phase 2 (33), Phase 1 (26), Phase 1/2 (12), Early Phase 1 (7). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 218Clinical trials
- 2New in 30 days
- 22Countries
Newest trials
All recruiting trials (newest 150 of 218)
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How age affects germinal center responses after flu and rabies vaccines
Researchers will test how the immune system responds to flu and rabies vaccines in younger adults (18–40) and older adults (65+).
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Cognitive Tasks and Models in a Large Online Sample
This study tests cognitive tasks and computational models in a large online group to see if these tools can help predict symptoms like hallucinations and delusions in the general population.
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Can seven tasks help distinguish schizophrenia and schizoaffective disorder from healthy people
The study tests seven cognitive tasks to see if they can tell apart people with schizophrenia or schizoaffective disorder from healthy adults and predict symptoms like hallucinations and delusions.
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Online perioperative education to support head and neck cancer patients and their caregivers
This trial tests a digital education program called CareOrbit to see if it improves understanding, satisfaction, and outcomes for adults with head and neck cancer undergoing reconstructive surgery or laryngectomy.
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Somatostatin analogues after PRRT for nonfunctional neuroendocrine tumors
This study tests whether continuing somatostatin analogues after PRRT helps patients with nonfunctional neuroendocrine tumors compared with just observation.
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ICG with near-infrared imaging to visualize head and neck cancer during surgery
This study tests whether first-window indocyanine green fluorescence seen during surgery matches the cancer extent seen on pathology in patients with head and neck squamous cell carcinoma.
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REACH: Resources and Education to Help Kids with Asthma in School
A service model called REACH will try to improve school-based asthma care by coordinating care between healthcare, school, and home for children with asthma.
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PET imaging of NPR-C in healthy adults using 64Cu-NODAGA-CANF (dosimetry)
This study tests how the radiotracer 64Cu-NODAGA-CANF distributes in the body and its safety in healthy adults.
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Amgdala–prefrontal circuits in fear extinction
This study tests how fear learning and extinction work in people with epilepsy who are already undergoing brain monitoring, by recording and stimulating Brain regions involved in fear.
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Navigation help for breast cancer patients with social needs
This study tests a patient navigator program to connect breast cancer patients with unmet social needs to community resources.
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Cerebrovascular Reactivity Testing with HD-DOT in Sickle Cell Patients
This study tests whether high-density diffuse optical tomography can measure brain blood flow and oxygen use in people with sickle cell disease, to see how these signals relate to stroke risk.
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Brain Imaging and Immune Changes During Remibrutinib in Relapsing MS
This study tests how remibrutinib affects brain inflammation in people with relapsing MS who are also on ocrelizumab.
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Personalized Movement Training to Help People with PMR Move Better
We’re testing whether a personalized Movement Pattern Training program can help people with polymyalgia rheumatica move more easily and reduce pain.
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Liposomal vs Standard Bupivacaine for Post-Rhinoplasty Pain
This study tests whether liposomal bupivacaine provides better pain control after rhinoplasty than standard bupivacaine.
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Using mHealth to Help Black Adults in the Midwest With Opioid/Stimulant Use and Mood Symptoms
This study tests a mobile health program to support recovery and mood in Black adults who use opioids or stimulants and are seeking treatment.
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Vagus nerve stimulation to help recovery after cervical spine decompression
This study tests whether transauricular vagus nerve stimulation can help people with moderate to severe degenerative cervical myelopathy recover better after decompression surgery.
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CCR2 PET Imaging for Head and Neck Squamous Cell Carcinoma
This trial tests whether Cu-64 DOTA-ECL1i PET/CT can reliably detect HNSCC in adults, including those with new locally advanced disease or suspected/confirmed recurrent/metastatic cancer.
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Support-TBI: Testing a partner-based program to help people with traumatic brain injury stay connected
A small pilot test will see if a partnered person with TBI and a close supporter can successfully participate in a 12-week program to improve social support and daily life participation.
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Lumateperone added to antidepressant therapy for older adults with treatment-resistant depression
A 10-week trial will test whether lumateperone helps reduce depression in people aged 60 and older who have not responded adequately to other antidepressants, compared with a placebo.
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Hypertension Treatment in Nigeria: HEARTS-D Integration for Diabetes Care
This program tests a HEARTS-D bundle in 10 primary health centers in Nigeria to help people with diabetes manage blood pressure and glucose using new tools and training.
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HFrEF polypill strategy in Sri Lanka
This study tests whether giving a heart failure polypill can reduce death from heart disease and hospitalizations in adults with HFrEF in Sri Lanka, compared with usual care.
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ENGAGE-TBI: A Feasibility Program to Reduce Social Isolation for Adults with Traumatic Brain Injury
We’re testing a 12-session group program to help adults with traumatic brain injury in the community build social participation and reduce isolation.
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DSP-0390 with Atezolizumab in extensive-stage small cell lung cancer
This pilot phase Ib study tests whether adding DSP-0390 to maintenance atezolizumab after initial chemo-immunotherapy is safe and shows early signs of activity in people with extensive-stage small cell lung cancer who have not progressed.
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Longitudinal versus transverse A1 pulley incision for trigger finger
This trial will test whether a straight (longitudinal) or a crease-based (transverse) skin incision leads to better hand function, less pain, and improved scarring after open A1 pulley release in adults with trigger finger.
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Home-based remote ischemic conditioning for people with spinal cord injury
This project will try remote ischemic conditioning at home to see if it improves heart and metabolic health in adults with spinal cord injury.
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PET scan to image MMP activity in abdominal aortic aneurysm
We will test whether a new PET tracer ([64Cu]-RYM2) can safely image MMP activity in people with abdominal aortic aneurysm and in healthy volunteers.
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Blood protein markers and heart changes in pregnant women with preeclampsia
This study tests whether blood proteins can reveal early heart changes in pregnant women with preeclampsia and uses heart ultrasound to see how the heart changes during pregnancy.
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Imaging inflammation in primary and metastatic brain tumors with [C-11]-CS1P1 PET
This trial will test a new PET tracer, [C-11]-CS1P1, in adults with primary or secondary brain tumors to see if tracer patterns of inflammation relate to MRI, treatments, and clinical outcomes.
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At-home HPV self-collection kits for cervical cancer screening
We are testing different ways to give at-home HPV self-collection kits to under-screened people aged 25–65 to see if more of them complete cervical cancer screening and follow-up.
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5-Fluorouracil Response and Optimization (FROST)
This trial will test two different dosing schedules of 5‑fluorouracil as second-line-or-later treatment for people with recurrent or metastatic head and neck squamous cell carcinoma who have already had platinum and PD‑1 inhibitor therapy.
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Non-invasive vagus nerve stimulation to lower inflammation and brain injury markers after acute ischemic stroke
This test tries whether adding non-invasive vagus nerve stimulation to usual care lowers inflammation and blood markers of brain injury in adults with acute ischemic stroke from a large vessel occlusion.
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Spatiotemporal spinal stimulation to improve leg movement after a spinal cord injury
This project tests whether changing the location, frequency, and intensity of non-invasive spinal stimulation can more precisely activate leg muscles in people with chronic spinal cord injury who can still voluntarily contract some leg muscles.
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Motixafortide to boost MRD testing in AML after induction
This study tests whether a single dose of motixafortide can change how accurately doctors measure measurable residual disease in AML patients who have finished induction therapy.
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CTX-009 alone or with CTX-471 for recurrent glioblastoma
This study tests CTX-009 by itself and in combination with CTX-471 to see if they can control tumors and help people living with recurrent glioblastoma.
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Text-message support and health information for people with spinal cord injury
This pilot will test whether a 16-week program of supportive and condition-specific text messages can help adults with spinal cord injury better manage bowel/bladder issues, pain, pressure injuries, and mental health.
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RSK1 Inhibitor PMD-026 in myeloid malignancies
A first-in-human test of PMD-026, an oral drug that blocks RSK1, to see if it is safe and can help reduce spleen size and symptoms in people with myelofibrosis and related myeloid conditions.
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Position Monitoring System for beam-gated radiotherapy in chest and upper abdomen
This study tests a new patient position monitoring system to help track the tumor during radiation therapy for chest and upper-abdominal cancers.
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First-Line Ipilimumab, Nivolumab, and IL-15 Superagonist in Advanced or Recurrent NSCLC
A phase Ib/II study tests whether adding nogapendekin alfa inbakicept to nivolumab and ipilimumab helps people with stage IV or recurrent non-small cell lung cancer.
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Hypertension Care Expansion in Nigeria 2.0
This program tests a modified WHO HEARTS hypertension treatment bundle in adults with high blood pressure across five new Nigerian states to see if blood pressure can be better controlled.
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Caregiver questionnaire to detect suicide risk in 4–7 year olds at a behavioral health clinic
This project will try a caregiver-filled questionnaire to see if it helps find suicidal thoughts and behaviors in children ages 4 to 7 who are seen at a behavioral health clinic.
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Miro3D tissue scaffold for complex soft-tissue wounds and pressure ulcers
This trial will test whether adding the Miro3D tissue scaffold to usual wound care helps adults with complex soft-tissue wounds or chronic pressure ulcers heal faster over 12 weeks.
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Multi-modal imaging to track myofascial neck and shoulder pain
This project tests whether MRI, surface EMG, and fiber‑optic imaging can track treatment response in adults with chronic myofascial neck or shoulder pain.
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ChromoSeq testing in kids with ALL to help classify at diagnosis
This study tests how well ChromoSeq® genetic sequencing can classify pediatric and young adult patients with suspected ALL using samples collected at initial workup.
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CARE Tool to help patients understand cancer care costs
This study will test a web-based CARE Tool that gives adults with gynecologic, prostate, lung, or colorectal cancer clear information about treatment costs, insurance, and resources to help with medical bills.
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Tofersen for adults with ALS who do not have SOD1 mutations
This study will test whether tofersen given by lumbar puncture over 24 weeks lowers neurofilament light chain and is safe for adults with ALS who do not have SOD1 mutations.
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Cancer Care Companion communication tool for parents
Parents of children newly diagnosed with cancer can try an electronic health-record communication tool called Cancer Care Companion to see if it is acceptable, appropriate, and feasible for supporting care.
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Precision MRI screening for dense breasts using Prognosia Breast risk score
This study tests whether using the Prognosia Breast risk score with an MRI for women with very dense breasts and normal mammograms can reduce interval breast cancers.
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Phone-delivered healthy behavior programs to prevent insomnia in people with HIV with chronic pain
This test compares brief phone-delivered behavioral insomnia treatment versus brief phone-delivered mindfulness training to see if they reduce insomnia, ease chronic pain, and slow biological aging in adults with HIV who have ongoing pain.
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Bringing SMART inhaler therapy to community health clinics
This project will test a program that helps community clinic clinicians start using SMART inhaler treatment for adults with moderate to severe asthma.
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AI-generated personalized question lists to help people with lymphoma or multiple myeloma prepare for clinic visits.
This study will test whether AI-generated personalized question lists help people with lymphoma or multiple myeloma ask better questions and get more useful information during outpatient appointments.
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AI-driven tool to guide blood preparation before surgery
This tests an AI decision-support tool that helps clinicians decide which surgery patients should have blood prepared ahead of time to ensure timely transfusion for those who need it and avoid unnecessary preparation for those who don't.
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Low-count SPECT imaging to guide Radium-223 treatment for men with bone-metastatic prostate cancer
This study tests whether low-count quantitative SPECT can help tailor Radium-223 therapy for men with prostate cancer that has spread to the bones.
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Ear (auricular) vagus nerve stimulation to speed recovery after acute neurocritical illness
This trial will test whether noninvasive ear (auricular) vagus nerve stimulation helps adults admitted to the NeuroICU have fewer infections, need fewer tracheostomies, and leave the hospital sooner.
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Eating Disorder Chatbot to help adults
A CBT-based chatbot is being tested to see if it can help adults with clinical or subclinical eating disorders manage symptoms and behaviors.
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Ear (auricular) vagus nerve stimulation to lower inflammation after long spinal fusion
This trial will test whether non-invasive ear-based vagus nerve stimulation can lower inflammation, improve blood sugar control, and reduce pain after long-segment spinal fusion surgery.
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Understanding pain in juvenile idiopathic arthritis
This project will test whether temperature and pressure pain tests, questionnaires, and blood or saliva samples can help explain pain in kids and teens (ages 9–17) with juvenile idiopathic arthritis.
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Digital support to reduce self-stigma for pregnant and postpartum women with substance use disorder
This project will test whether a smartphone program called Enhearten can reduce self‑stigma and help pregnant and postpartum women with substance use disorder stay in treatment and improve recovery.
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Selinexor maintenance after CAR-T for multiple myeloma
This Phase 1 test will see if taking selinexor after ciltacabtagene autoleucel (cilta‑cel) helps adults with relapsed, triple-class exposed or refractory multiple myeloma stay in remission longer.
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NT-I7 added to BCMA CAR-T therapy for relapsed or refractory multiple myeloma
This trial tests whether giving NT-I7 after BCMA CAR-T therapy helps boost T-cell expansion and possibly improve responses in people with relapsed or refractory multiple myeloma.
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Multicontext Approach to Help Daily Thinking in Parkinson’s
This study tests whether a Multicontext strategy training program can improve daily thinking and function for people with early Parkinson’s who notice cognitive changes.
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FluMist versus injected flu shot: immune responses in the nose and lungs of young adults
This trial will see if the FluMist nasal vaccine causes different immune responses in the blood, nose, and lungs than the standard injected flu shot in healthy adults aged 18 to 40.
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Dapagliflozin (an SGLT2 inhibitor) for slowing geographic atrophy in dry AMD
This trial will test whether taking dapagliflozin once daily can slow the growth of geographic atrophy in people aged 50 and older with dry age-related macular degeneration.
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Personalized treatment to help people with cancer quit smoking and live longer
We will test whether personalized tobacco treatment using clinical, genetic, and biomarker information helps cancer patients who smoke quit and use cessation medications more than usual care.
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Cirtuvivint plus irinotecan for relapsed small-cell lung cancer
This trial will test whether adding cirtuvivint to irinotecan helps people with relapsed small-cell lung cancer respond better and live longer.
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Pink and Pearl campaign to link mammography visits with lung cancer screening at Christian Hospital.
This program will try to increase lung cancer screening among women aged 50–80 who come for mammograms at Christian Hospital.
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Mandibular advancement to reduce sleep apnea after hypoglossal nerve stimulation
This will try a mandibular advancement device (a mouthpiece worn at night) to see if it reduces moderate to severe obstructive sleep apnea in adults who cannot tolerate CPAP and whose hypoglossal nerve stimulation did not help enough.
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Combining SBRT with defactinib and avutometinib for advanced pancreatic cancer
This Phase 2 trial tests whether adding the targeted drugs defactinib and avutometinib to adaptive SBRT helps people with locally advanced or borderline resectable pancreatic cancer stay progression-free longer than SBRT alone.
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PET scan with [18F]-FZTA to detect brain inflammation in people with MS and healthy younger adults
This test tries a new PET tracer called [18F]-FZTA to see if it detects brain inflammation in adults with multiple sclerosis and in healthy younger adults.
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EHR-based annual PSA reminder and shared decision-making program across a 10-hospital system
This trial will test whether an annual electronic health record reminder that prompts shared decision-making and guideline-based referral improves PSA screening and appropriate follow-up for men at average or high risk in a large health system.
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Emavusertib with cisplatin, gemcitabine, and durvalumab for untreated advanced biliary tract cancer
This trial tests whether adding emavusertib to standard cisplatin, gemcitabine, and durvalumab helps adults with untreated advanced or metastatic biliary tract cancer.
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Daily ketone ester drink to lower liver fat and improve metabolism
This trial tests whether a daily ketone ester drink for 6 weeks can reduce liver fat and improve blood sugar control in 18–25-year-olds with MASLD who are overweight or have obesity.
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Smartphone chatbot to prevent eating disorders in teens
This project will test a smartphone chatbot program to prevent eating disorders in 13–17-year-olds who are at risk and not currently in treatment.
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24 mg versus 10 mg daily lenvatinib for symptomatic or progressive radioactive iodine–resistant differentiated thyroid cancer
This trial tests whether a higher (24 mg) or lower (10 mg) daily dose of lenvatinib works better and is easier to tolerate for people with symptomatic or progressive radioactive iodine–resistant differentiated thyroid cancer.
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Semaglutide plus exercise training for people with obesity and reduced physical function
This two-year trial will test whether semaglutide, with or without a supervised exercise program, helps people with obesity and decreased physical function keep muscle mass, strength, and metabolic health and what happens after the medication is stopped.
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Comparing mandibular advancement devices and hypoglossal nerve stimulation for obstructive sleep apnea
This study will test whether mandibular advancement devices or hypoglossal nerve stimulation work better for adults with moderate-to-severe obstructive sleep apnea who can't use or won't tolerate CPAP.
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COMPASS: Home transition program to reduce disability after stroke
This program will test whether a home-focused environmental modifications intervention helps people aged 55 and older returning home from inpatient stroke rehabilitation do everyday activities better than a standard stroke education program.
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NT-I7 (efineptakin alfa) given after Yescarta or Breyanzi for relapsed/refractory large B‑cell lymphoma
This trial tests whether giving NT-I7, a long‑acting IL‑7, after CAR T‑cell therapy (Yescarta or Breyanzi) helps people with relapsed/refractory large B‑cell lymphoma recover T cells and improve outcomes.
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Improving team-based biopsychosocial training so clinics can deliver recommended obesity care
This project will test two training methods to help clinic teams (primary care clinicians, behavioral health staff, dietitians, and community health workers) deliver USPSTF-recommended obesity care to patients at Federally Qualified Health Centers.
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Culturally adapted mindfulness to support thinking and memory in Latino older adults
This study will test whether an 8-week culturally adapted mindfulness program can improve cognitive function, daily mindfulness, and brain/blood markers related to Alzheimer’s in Latino adults aged 65 and older.
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Adapted Home Hazard Removal Program (HARP) for adults with physical disabilities
This pilot tests whether an adapted Home Hazard Removal Program (HARP) can reduce falls and improve home safety for community-dwelling adults aged 45–64 with long-term physical disabilities.
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Brain imaging to map a newly discovered motor-control network in Parkinson's disease.
Using MRI, researchers will see if a newly discovered brain network called the Somato-Cognitive Action Network (SCAN) is altered in people with Parkinson's disease.
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Siltuximab for antibody-mediated rejection after lung transplant
This study will test whether adding siltuximab, an IL‑6 blocker, to standard treatment is safe and tolerable for adults hospitalized with antibody-mediated rejection after lung transplant.
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ChatGPT and surgeon teamwork to improve breast reconstruction consultations
This project will test whether ChatGPT-generated patient education materials help people preparing for breast reconstruction understand their options and feel more satisfied with their surgeon consultations.
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Tirzepatide to heal small-bowel Crohn's disease after failure of advanced therapies
This trial will test whether tirzepatide can help heal ileal or ileocolonic Crohn's disease in adults whose inflammation has not responded to at least two advanced treatments.
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Fluvoxamine to reduce delirium after non-cardiac surgery
This study will test whether giving fluvoxamine around the time of elective non-cardiac, non-intracranial surgery can help reduce postoperative delirium in older adults who will stay in the hospital at least two days.
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Zanzalintinib plus eribulin for advanced liposarcoma and leiomyosarcoma
This trial tests whether adding zanzalintinib to eribulin helps adults with advanced liposarcoma or leiomyosarcoma live longer without their cancer getting worse.
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Using buprenorphine for pain relief after ankle fracture surgery
This study tests if a skin patch with buprenorphine can help manage pain after ankle fracture surgery for patients who haven't used opioids before, while also looking at safety and the risk of addiction.
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Zanzalintinib maintenance for high-grade neuroendocrine neoplasms
This trial tests whether taking zanzalintinib after initial chemotherapy can keep high-grade neuroendocrine tumors from growing longer in people with these cancers.
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ONT01 plus gemcitabine and nab-paclitaxel as second-line treatment for metastatic pancreatic cancer
This trial tests whether adding ONT01 to gemcitabine and nab-paclitaxel helps people with metastatic pancreatic ductal adenocarcinoma who need second-line therapy.
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Evaluating the Pink and Pearl Campaign for Lung Cancer Screening
This study is testing if the Pink and Pearl Campaign can encourage women aged 50-80 getting mammograms to also get screened for lung cancer.
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Using AI to improve monitoring of Kaposi Sarcoma
This study is testing a new low-cost device that uses AI to help doctors better track and measure Kaposi Sarcoma in patients with darker skin in Uganda and Kenya.
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Understanding how a ketogenic diet affects cholesterol levels
This study is testing how a very-low carbohydrate ketogenic diet affects cholesterol levels in normal-weight adults who might be more likely to have high cholesterol on this diet.
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Using propofol to improve sleep and reduce depression in older adults
This study is testing if using propofol to improve sleep, along with short therapy sessions, can help older adults feel less depressed.
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WashU animated video explaining DIEP flap breast reconstruction
English-speaking adults scheduled for DIEP breast reconstruction will watch a WashU animated video to see if it improves their understanding and lowers anxiety before and after surgery.
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Improving heart health for pregnant women with high blood pressure in Nigeria
This study is testing a new program to help pregnant women in Nigeria with high blood pressure manage their condition better after giving birth.
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Examining immune responses to influenza and COVID-19 infections
This study is testing how people's immune systems respond to influenza and COVID-19 infections by comparing vaccinated and unvaccinated individuals.
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Neoadjuvant chemoradiotherapy with or without azeliragon for newly diagnosed glioblastoma
This will test whether adding azeliragon to standard radiation and temozolomide before repeat tumor sampling can reduce immune-suppressive myeloid cells and boost T-cell activity in adults with newly diagnosed glioblastoma.
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Combination treatment for chronic nasal obstruction
This study is testing if a combination of a nasal spray and steroids can help people with chronic nasal obstruction who haven't found relief with regular treatments.
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Investigating the impact of KATP channel loss on insulin secretion in type 2 diabetes
This study is testing how a medication called glipizide affects insulin release in people with type 2 diabetes to see if losing certain channels in the body makes it harder to manage blood sugar, especially in those who are obese.
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Using auricular vagus nerve stimulation to improve outcomes after brain bleeding
This study is testing if a new type of ear stimulation can help people recover better and have fewer complications after bleeding in the brain.
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Zanzalintinib with paclitaxel for recurrent high-grade uterine cancer
This trial tests whether adding zanzalintinib to paclitaxel is safe and helps people with recurrent high-grade uterine (endometrial) cancer respond to treatment.
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Investigating pain and hormone levels in migraine and endometriosis patients
This study is trying to see how pain responses and hormone levels differ in people with migraines, endometriosis, both conditions, and healthy individuals.
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Exploring how rejection sensitivity and puberty affect mental health in early adolescent girls using social media
This study looks at how feelings of rejection and going through puberty affect the mental health of girls aged 10-11 who use social media.
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Using advanced imaging to evaluate Kaposi sarcoma
This study is testing if a special 3D camera can help doctors get better images of Kaposi sarcoma skin lesions in patients to track how well treatments are working.
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Using light therapy to help young adults with OCD
This study is testing whether wearing light therapy glasses for an hour each morning can help young adults with OCD who stay up late feel better and improve their sleep patterns.
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De-escalation of treatment for HPV-related throat cancer
This study is testing a new way to treat HPV-related throat cancer that aims to use less intense therapy after surgery to lower side effects while still keeping the cancer under control.
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A tool to improve family communication in pediatric stem cell transplant decisions
This study is testing a new tool to help families talk better and make decisions together about stem cell transplants for kids aged 8 to 17.
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Preventing CNS relapse in high-risk diffuse large B-cell lymphoma with thiotepa-based treatment
This study is testing if a special treatment using thiotepa can help newly diagnosed patients with high-risk diffuse large B-cell lymphoma avoid relapsing in the brain after their stem cell transplant.
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MK2 inhibitor combined with chemotherapy for advanced pancreatic cancer
This study is testing if a new drug called Zunsemetinib can make chemotherapy work better for people with untreated advanced pancreatic cancer.
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Testing a new treatment for early onset Alzheimer's disease caused by genetic mutations
This study is testing a new drug called remternetug to see if it can help prevent or reverse early onset Alzheimer's disease in people with genetic mutations.
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Exploring how language affects fertility treatment progress
This study is testing whether Spanish-speaking patients have a better experience and faster progress in fertility treatments when they communicate with a Spanish-speaking provider instead of using an interpreter.
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Testing DSP-0390 in patients with IDH-mutant gliomas
This study is testing a new drug called DSP-0390 in patients with specific types of brain tumors to see if it helps kill more tumor cells during surgery.
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Improving maternal outcomes during prolonged labor with position changes
This study is testing if changing positions during prolonged labor can help women have better outcomes and feel more satisfied compared to standard care.
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Using radiation and chemotherapy before CAR T-cell therapy for multiple myeloma patients with kidney issues
This study is testing if using low-dose radiation and chemotherapy before CAR T-cell therapy can help people with multiple myeloma and kidney problems get better results.
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Understanding inflammation in relapsing remitting Multiple Sclerosis
This study looks at the type of inflammation in people with relapsing remitting Multiple Sclerosis to see why some inflammation sticks around even after treatment and how this might help improve future therapies.
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Embedding palliative care in the medical ICU
This study is testing whether having a palliative care specialist in the ICU can help critically ill patients get better care and improve their outcomes compared to those who don’t have this support.
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Using phage therapy to treat bladder infections in spinal cord injury patients
This study is testing if a new treatment using viruses to target bacteria can help people with spinal cord injuries who have bladder infections caused by E. coli.
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Comparing two radiation therapies for node-positive breast cancer
This study is testing if a new type of radiation therapy that gives higher doses in fewer sessions can help people with node-positive breast cancer just as well as the standard treatment, while also making their lives easier.
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Group care program for treating endometriosis-related pain
This study is testing a new group care program called PEEPS to see if it can help people aged 18 to 48 with endometriosis-related pain feel better compared to those who just get regular support.
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Understanding blood biomarkers for Alzheimer's disease
This study is testing if certain blood markers can help identify and predict Alzheimer's disease in people aged 60 and older.
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Using pacritinib to treat VEXAS syndrome
This study is testing if the drug pacritinib can help people with VEXAS syndrome feel better and manage their symptoms.
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Personalized cancer vaccine for patients with muscle-invasive bladder cancer
This study is testing a personalized cancer vaccine to see if it can help patients with muscle-invasive bladder cancer fight their disease by boosting their immune response.
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New treatment approach for locally advanced cervical cancer
This study is testing a new treatment for locally advanced cervical cancer that combines different types of radiation and chemotherapy to see if it can improve recovery and reduce side effects for patients.
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Testing a ketogenic diet for better blood sugar control in type 1 diabetes
This study is testing if a very-low-carbohydrate ketogenic diet can help adults with type 1 diabetes manage their blood sugar better and reduce their need for insulin.
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Personalized maintenance treatment for multiple myeloma after stem cell transplant
This study tests a personalized treatment plan using a new immunotherapy drug for people with multiple myeloma after a stem cell transplant to see if it helps them stay in remission longer.
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Propranolol for treating Kaposi sarcoma in adults
This trial will test whether the oral beta‑blocker propranolol can shrink Kaposi sarcoma lesions in adults, including people living with HIV.
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Using a new imaging agent to study Alzheimer's disease
This study is testing a new imaging agent to see how well it can help visualize Alzheimer's disease and its effects on the brain in both healthy people and those with mild cognitive impairment.
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Using local anesthesia to manage pain in facial fracture surgery
This study is testing if using a local pain medication during facial fracture surgery can help patients recover better and use less pain relief afterward.
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PREVENT: a digital tool to tailor diet and activity counseling in rural primary care
This pilot will test whether the PREVENT digital tool helps low-income rural adults with obesity get more personalized diet and physical activity advice during primary care visits.
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Using lidocaine to reduce pain from benzathine penicillin injections for syphilis treatment
This study is testing if adding lidocaine to syphilis treatment injections can help reduce the pain patients feel during and after the shot.
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Rivastigmine for antimuscarinic delirium
This trial tests whether rivastigmine can help people 10 years and older with antimuscarinic delirium recover faster than with a placebo.
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Combining zunsemetinib with capecitabine for advanced breast cancer with bone metastasis
This study is testing if combining zunsemetinib with capecitabine can help people with advanced breast cancer that has spread to the bones feel better and improve their treatment outcomes.
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Evaluating hepatitis C treatment during pregnancy
This study tests how well a new hepatitis C treatment works for pregnant adults with a history of drug use and looks at their experience during the treatment.
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Engaging cancer patients in genomic testing decisions
This study is testing if letting cancer patients choose what genetic information they want to receive helps them feel more informed and satisfied with their health decisions.
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Nerve transfer surgery to enhance function in high tetraplegia
This study is testing if nerve transfer surgery can help people with high spinal cord injuries improve their arm function and quality of life.
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Using enasidenib to treat clonal cytopenia of undetermined significance
This study is testing if a drug called enasidenib can help people with unexplained low blood cell counts and a specific gene mutation feel better and improve their health.
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Testing a new CAR-T therapy for multiple myeloma
This study tests a new CAR-T therapy to see if it can help people with tough-to-treat multiple myeloma feel better after other treatments haven't worked.
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Investigating brain network changes in children with brain tumors after radiation therapy
This study is trying to see how radiation therapy changes brain connections in children with brain tumors and how those changes might affect their thinking skills after treatment.
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Enhancing stem cell transplant for children with high-risk acute myeloid leukemia
This study is testing a new way to improve stem cell transplants for children and young adults with high-risk acute myeloid leukemia by using half-matched family donors and special immune cells to make the treatment safer and more effective.
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Radiotherapy plus a STAT3 blocker for borderline resectable or locally advanced pancreatic cancer
Researchers are testing whether adding a STAT3-inhibiting drug (TTI-101) to SBRT can help patients with borderline resectable or locally advanced pancreatic cancer see better outcomes.
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Investigating brain inflammation in Alzheimer's disease using a new imaging tracer
This study is testing a new imaging tool to see if it can help spot brain inflammation in older adults, including those with Alzheimer's disease and related conditions.
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Understanding pain in patients with endometriosis and pelvic pain
This study looks at what causes chronic pelvic pain in people with and without endometriosis and checks how pain and hormone levels change after surgery to remove endometriosis lesions.
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Using PREVENT, a digital tool to improve heart‑healthy counseling in rural primary care
This trial will test whether PREVENT, a clinic‑based digital tool, helps adults aged 18–64 with obesity in rural, low‑income communities get better counseling and resources to lower their heart disease risk.
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Examining the link between sex hormones, pain after surgery, and opioid use
This study is trying to see if levels of sex hormones like testosterone affect pain and opioid use in young girls aged 11-16 after they have orthopedic surgery.
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Training program to improve health for wheelchair users
This study is testing a new training program to help wheelchair users improve their health by being more active and seeing if it works better than just providing education and support.
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Using Ruxolitinib to prevent complications after haploidentical stem cell transplants
This study is testing if the drug Ruxolitinib can help prevent complications like graft-versus-host disease in patients receiving stem cell transplants from partially matched donors.
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Understanding tumor types in patients with primary hyperparathyroidism
This study is trying to see how often different types of tumors occur in people with primary hyperparathyroidism who are having surgery to remove their parathyroid glands.
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Comparing recovery after different anesthesia techniques in surgery
This study is testing whether recovery is better after surgery using either intravenous propofol or inhaled anesthesia for different types of surgeries.
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Biomarker-driven treatment selection for metastatic breast cancer
This study is testing if measuring a specific blood marker can help doctors decide when to change treatments for patients with certain types of advanced breast cancer to improve their chances of staying cancer-free longer.
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Assessing the effects of radiotherapy on tumors in cervical and pancreatic cancer
This study is testing how radiotherapy affects tumors in patients with locally advanced cervical and pancreatic cancer by collecting samples and using special imaging before, during, and after treatment.
Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.
Quick answers
How many clinical trials run by Washington University School of Medicine are recruiting right now?
218, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 22 countries. The most sites are in United States (211 trials), Canada (6 trials), Nigeria (5 trials), United Kingdom (4 trials), Argentina (3 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 33, Phase 1: 26, Phase 1/2: 12, Early Phase 1: 7. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.