ENGAGE-TBI: A Feasibility Program to Reduce Social Isolation for Adults with Traumatic Brain Injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a Phase 1 feasibility study that will enroll 30 adults with traumatic brain injury living in the St. Louis area to try the ENGAGE-TBI intervention. The program blends social learning, guided problem-solving, and real-world practice over six weeks, co-facilitated by an occupational therapist and a peer mentor with TBI. Outcomes will focus on feasibility metrics such as fidelity, engagement, attendance, retention, and satisfaction, with preliminary changes in social participation measured by PROMIS. A single-group pre-post design will estimate effect sizes to inform future studies. Findings will help determine whether broader testing of ENGAGE-TBI is warranted in community settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* at least 18 years old
* experienced a TBI \> 6 months prior to enrollment, confirmed by a physician as documented in their medical record
* live in the St. Louis area
* report problems with social participation (retention of \< 80% of pre-TBI social activities as measured by Activity Card Sort)

Exclusion Criteria:

* insufficient English language fluency to participate in the group intervention
* have active substance use disorder (PRIME-MD MINI)
* have an untreated psychotic disorder (PRIME-MD MINI)
* have severe memory impairment that would limit their ability to recall strategies with support (Montreal Cognitive Assessment, \< 21)

Where it's running

• Washington University School of Medicine
  St Louis, Missouri, United States Recruiting

Study contacts

• Study coordinator: Jessica Kersey, PhD, OTR/L Assistant Professor, PhD, OTR/L
• Email: jkersey@wustl.edu
• Phone: +1 314 273 7540

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.