Using local anesthesia to manage pain in facial fracture surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial is a double-blind randomized, placebo-controlled study that investigates the effects of perioperative bupivacaine nerve blocks on recovery metrics in patients undergoing surgery for facial fractures. Participants with isolated mandibular or midface fractures are randomly assigned to receive either bupivacaine or saline injections before waking from anesthesia. The primary goal is to assess the reduction in opioid and antiemetic use in the post-anesthesia care unit (PACU), which is crucial for improving patient outcomes and reducing hospital costs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Adults age 18 and over
2. Isolated facial fracture to the mandible and/or midface undergoing surgical repair
3. No allergy to local anesthetic
4. Ability to read, write, and understand English

Exclusion Criteria:

1. Patients under the age of 18
2. Isolated nasal bone fracture
3. Polytrauma (I.e. injury pattern resulting in hospital admission for multiple bony fractures outside of the face)
4. Allergy to local anesthetic

Where it's running

• Washington University
  St Louis, Missouri, United States Recruiting

Study contacts

• Principal investigator: Amrita Hari_Raj, MD — Washington University School of Medicine
• Study coordinator: Amrita Hari-Raj, MD
• Email: amrita.hari-raj@wustl.edu
• Phone: 314-518-6410

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.