Understanding blood biomarkers for Alzheimer's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the relationships between blood-based biomarkers, specifically amyloid, tau, and neurodegeneration, and their association with Alzheimer's disease pathology and cognitive decline. Eligible participants aged 60 and older will undergo initial cognitive assessments and blood collection, with follow-up visits for additional testing based on their cognitive status. The goal is to validate blood tests that could aid in the diagnosis and prediction of Alzheimer's disease.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* At least 60 years of age
* 80% of the newly enrolled clinic-based cohort will have symptoms of forgetfulness, mild cognitive impairment, mild dementia, or Alzheimer's disease as determined by their medical chart and/or provider
* All SEABIRD participants will be invited to participate regardless of their cognitive status

Exclusion Criteria:

* Unable to perform one or more basic activities of daily living (eating, bathing, dressing, ambulating, toileting) due to cognitive impairment
* Uncontrolled hepatitis B, hepatitis C, or HIV at time of blood collection
* Taking a disease-modifying drug for AD at time of enrollment
* Blood transfusion in the last three months
* Unwilling or unable to participate in all study activities

Where it's running

• Washington University School of Medicine
  St Louis, Missouri, United States Recruiting

Study contacts

• Principal investigator: Randall Bateman, MD — Washington University School of Medicine
• Study coordinator: Lisa Soke
• Email: sunbirdstudy@wustl.edu
• Phone: 314-747-4857

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.