ChromoSeq testing in kids with ALL to help classify at diagnosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects bone marrow and/or blood samples from up to 60 children and young adults with suspected ALL to try ChromoSeq® for upfront classification in real time. Patients are followed for clinical outcomes for up to about five and a half years. The protocol does not prescribe treatment choices and allows concurrent participation in other therapeutic trials. The aim is to determine the feasibility of using this sequencing assay as part of standard care to guide initial classification of ALL. Enrollment is at St. Louis Children’s Hospital/Washington University in St. Louis.

Why it matters

Who can join: the full rules

Eligibility Criteria

* Children and young adult patients (\< 30 years of age at time of study enrollment) treated at St. Louis Children's Hospital/Washington University School of Medicine.
* Suspected diagnosis or suspected relapse of acute lymphoblastic leukemia (ALL), B- or T-cell.
* Concurrent enrollment on a prospective therapeutic trial is allowed as this protocol makes no recommendations regarding treatment approach.
* Ability to understand and willingness to sign an IRB approved written informed consent document. All patients and/or their parents or legal guardians must sign an IRB approved written informed consent document.

Where it's running

• Washington University School of Medicine/St. Louis Children's Hospital
  St Louis, Missouri, United States Recruiting

Study contacts

• Principal investigator: Margaret Ferris, MD, PhD — Washington University School of Medicine
• Study coordinator: Margaret Ferris, MD, PhD
• Email: youngm@wustl.edu
• Phone: 314-454-6018

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.