Clinical trial Recruiting at 1 site Interventional Ages 10 and up Women only

Exploring how rejection sensitivity and puberty affect mental health in early adolescent girls using social media

Official title: Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls

Run by Washington University School of Medicine · NCT06777823 · Data updated 2026-11-12

This study looks at how feelings of rejection and going through puberty affect the mental health of girls aged 10-11 who use social media.

Quick facts

Study typeInterventional
Ages10 Years and up
SexWomen only
Enrollment250 (estimated)
SponsorWashington University School of Medicine
Academic / other
Locations1 site (St Louis, Missouri)
StatusRecruiting
StartedFebruary 5, 2025
Main results expectedJune 1, 2028
Study endsJune 30, 2029
Registry record updatedMay 6, 2026
Trial IDNCT06777823 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are girls aged 10-11 who actively use social media and can communicate in English.

Probably not a fit

Patients with chronic medical illnesses, autism spectrum disorder, significant developmental delays, or those not assigned female at birth may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This longitudinal study investigates the bidirectional relationships between mental health and social media experiences in preteen girls aged 10-11. It focuses on how pubertal development and experiences of rejection influence these relationships. Participants will engage in a social rejection task and complete daily diaries to track their experiences. The study aims to provide insights into the mental health vulnerabilities associated with social media use during this critical developmental period.

Why it matters

Potential benefit: If successful, this study could help identify mental health vulnerabilities in early adolescent girls and inform interventions to support their well-being.

How similar studies have gone: While studies on social media's impact on mental health are common, this specific focus on rejection sensitivity and puberty in early adolescent girls is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* female aged 10-11 years
* engagement in social media use
* proficient in the English language
* family/personal device that can complete daily diaries

Exclusion Criteria:

* previously diagnosed chronic medical illness
* autism spectrum disorder
* significant developmental or speech delay
* endocrine disorder
* not assigned female at birth (AFAB)

Where it's running

  • Washington University School of Medicine
    St Louis, Missouri, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.