Hypertension Care Expansion in Nigeria 2.0
Official title: Hypertension Treatment in Nigeria Program 2.0
Run by Washington University School of Medicine · NCT07351162 · Data updated 2026-11-12
This program tests a modified WHO HEARTS hypertension treatment bundle in adults with high blood pressure across five new Nigerian states to see if blood pressure can be better controlled.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Washington University School of Medicine Academic / other |
| Locations | 49 sites (Mbalano, Abia State and 48 other locations) |
| Status | Recruiting |
| Started | February 2, 2026 |
| Main results expected | January 31, 2029 |
| Study ends | January 31, 2030 |
| Registry record updated | October 14, 2026 |
| Trial ID | NCT07351162 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 and older with elevated blood pressure or a history of hypertension, including pregnant or cognitively impaired adults, in the specified Nigerian PHCs.
✕Probably not a fit
Patients without elevated blood pressure or not receiving care at the participating PHCs may not experience direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
HTN 2.0 builds on the prior HTN program by expanding the HEARTS bundle to Abia, Delta, Gombe, Jigawa, and Oyo, while checking whether hypertension control is sustained in the capital. The intervention uses a standardized package for hypertension care at primary health centers, adapted for the local context. Eligible participants include adults with elevated blood pressure, those already on BP-lowering meds, pregnant women, and adults with cognitive impairment. Exclusions cover individuals under 18 and detained persons. Lead sponsorship comes from Washington University School of Medicine, with collaboration from Nigerian partners and NHLBI, at select PHCs in Abia State.
Why it matters
Potential benefit: If successful, the program could improve blood pressure control for adults in multiple Nigerian states and sustain gains from the original HTN program.
How similar studies have gone: Previous HTN program in Nigeria demonstrated improved treatment and control using the HEARTS package, supporting potential benefit for HTN 2.0.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (≥18 years old), * Elevated blood pressure (SBP ≥ 140 mmHg or DBP ≥ 90 mmHg) documented or measured by a health care professional (e.g., physician, community health extension worker, or community health officer) on two separate occasions or taking a BP-lowering medication, or a history of hypertension. * Pregnant women are eligible for this program, or * Cognitively impaired adults are eligible for this program.. Exclusion Criteria: This program will not include any of the following special populations: * Individuals who are not yet adults (minors): i.e. infants, children, or teenagers \<18 years old, or * Prisoners or other detained individuals.
Where it's running
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Amiyi Uhu PHC
Mbalano, Abia State, Nigeria Recruiting -
Mbagwu PHC
Mbalano, Abia State, Nigeria Recruiting -
Nunya Health Centre
Mbalano, Abia State, Nigeria Recruiting -
Nvurunvu PHC
Mbalano, Abia State, Nigeria Recruiting -
Onuaku PHC
Mbalano, Abia State, Nigeria Recruiting -
Amaeke PHC
Umuahia, Abia State, Nigeria Recruiting
Show 43 more locations
-
Isiama Afara PHC
Umuahia, Abia State, Nigeria Recruiting -
Oriendu PHC
Umuahia, Abia State, Nigeria Recruiting -
Umuda Isingwu PHC
Umuahia, Abia State, Nigeria Recruiting -
Umukabia PHC
Umuahia, Abia State, Nigeria Recruiting -
Igun PHC
Eku, Delta, Nigeria Recruiting -
Okpara Waterside PHC
Eku, Delta, Nigeria Recruiting -
Orhondo-Eku PHC
Eku, Delta, Nigeria Recruiting -
Edjemuyavwe PHC
Oghara, Delta, Nigeria Recruiting -
Jesse PHC
Oghara, Delta, Nigeria Recruiting -
Oghareki PHC
Oghara, Delta, Nigeria Recruiting -
Amukpe PHC
Sapele, Delta, Nigeria Recruiting -
Gana PHC
Sapele, Delta, Nigeria Recruiting -
Urban PHC
Sapele, Delta, Nigeria Recruiting -
Abuja PHC
Gadam, Gombe State, Nigeria Recruiting -
Gadam PHC
Gadam, Gombe State, Nigeria Recruiting -
Kumbiya Kumbiya PHC
Gombe, Gombe State, Nigeria Recruiting -
Madaki PHC
Gombe, Gombe State, Nigeria Recruiting -
Nassarawo PHC
Gombe, Gombe State, Nigeria Recruiting -
Pantami PHC
Gombe, Gombe State, Nigeria Recruiting -
Town PHC
Gombe, Gombe State, Nigeria Recruiting -
Tudun Wada PHC
Gombe, Gombe State, Nigeria Recruiting -
Bogo PHC
Kumo, Gombe State, Nigeria Recruiting -
Kumo PHC
Kumo, Gombe State, Nigeria Recruiting -
Bamaina PHC
Birnin Kudu, Jigawa State, Nigeria Recruiting -
Magajin Gari PHC
Birnin Kudu, Jigawa State, Nigeria Recruiting -
Sudumina PHC
Birnin Kudu, Jigawa State, Nigeria Recruiting -
Kachi PHC
Dutse, Jigawa State, Nigeria Recruiting -
Kudai PHC
Dutse, Jigawa State, Nigeria Recruiting -
Sakwaya PHC
Dutse, Jigawa State, Nigeria Recruiting -
Andaza PHC
Kiyawa, Jigawa State, Nigeria Recruiting -
Katanga PHC
Kiyawa, Jigawa State, Nigeria Recruiting -
Kiyawa PHC
Kiyawa, Jigawa State, Nigeria Recruiting -
Ogharefe PHC
Oghara, Ogharefe, Nigeria Recruiting -
Ojoo PHC
Akinyele, Oyo State, Nigeria Recruiting -
Alakia Model PHC
Egbeda, Oyo State, Nigeria Recruiting -
Alegongo PHC
Ibadan, Oyo State, Nigeria Recruiting -
Apete PHC
Ibadan, Oyo State, Nigeria Recruiting -
Idi Ogungun PHC
Ibadan, Oyo State, Nigeria Recruiting -
Iwo Road PHC
Ibadan, Oyo State, Nigeria Recruiting -
Odo-Ona Elewe PHC
Ibadan, Oyo State, Nigeria Recruiting -
Oke Bola PHC
Ibadan, Oyo State, Nigeria Recruiting -
Oniyanrin PHC
Ibadan, Oyo State, Nigeria Recruiting -
Oranyan PHC
Ibadan, Oyo State, Nigeria Recruiting
Study contacts
- Study coordinator: Dike Ojji, MD
- Email: dike.ojji@uniabuja.edu.ng
- Phone: +234-806-009-4456
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.