Group care program for treating endometriosis-related pain

Interdisciplinary Group Care for the Treatment of Endometriosis-associated Pain: the Peer Empowered Endometriosis Pain Support (PEEPS) Pilot Randomized Controlled Trial

Not applicable Interventional Washington University School of Medicine · NCT06549985

This study is testing a new group care program called PEEPS to see if it can help people aged 18 to 48 with endometriosis-related pain feel better compared to those who just get regular support.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 48 Years
SexFemale
SponsorWashington University School of Medicine Academic / other
Locations1 site (St Louis, Missouri)
Trial IDNCT06549985 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of the Peer Empowered Endometriosis Pain Support (PEEPS) program, an 8-week interdisciplinary group care initiative aimed at reducing pain interference in individuals aged 18 to 48 with endometriosis-associated chronic pelvic pain. Participants will engage in group sessions that incorporate integrative care strategies, including pelvic floor physical therapy and mindfulness techniques. The study compares outcomes between those receiving PEEPS alongside usual care and those receiving educational support with usual care, assessing improvements in pain, physical function, and quality of life through surveys and feedback mechanisms.

Who should consider this trial

Good fit: Ideal candidates are women aged 18-48 with a confirmed diagnosis of endometriosis and chronic pelvic pain lasting six months or more.

Not a fit: Patients who are currently pregnant, have severe physical impairments, or a history of psychiatric disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly reduce pain and improve the quality of life for patients suffering from endometriosis-related pain.

How similar studies have performed: Other studies have shown promise in using integrative group care approaches for chronic pain management, suggesting potential success for this novel program.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-48 years
* Operative confirmation of endometriosis
* Chronic pelvic pain (pain perceived to originate from the pelvis, not exclusively during menses, lasting ≥6 months)
* No plan to have surgery before or during the PEEPS cohort
* Able to attend at least six of the eight 2-hour weekly sessions on the Washington University campus
* Comfort reading and speaking English as groups and materials are in English

Exclusion Criteria:

* Currently pregnant
* Severe physical impairment (limiting yoga participation)
* History of hip or spine surgery given increased risk of harm and need for extensive activity modification
* Current or history of psychiatric disorder with psychosis in order to minimize risk of adverse mental health effects to participants
* Opioid use ≥ 5 days in the past 3 months, other than for the 6-week post-operative period
* History of surgical removal of bilateral ovaries

Where this trial is running

St Louis, Missouri

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions EndometriosisPelvic PainGroup careIntegrative carePelvic floor physical therapyMindfulnessPatient-centered outcomes
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.