Clinical trial Recruiting at 1 site Interventional Ages 18 to 48 Women only

Group care program for treating endometriosis-related pain

Official title: Interdisciplinary Group Care for the Treatment of Endometriosis-associated Pain: the Peer Empowered Endometriosis Pain Support (PEEPS) Pilot Randomized Controlled Trial

Run by Washington University School of Medicine · NCT06549985 · Data updated 2026-11-12

This study is testing a new group care program called PEEPS to see if it can help people aged 18 to 48 with endometriosis-related pain feel better compared to those who just get regular support.

Quick facts

Study typeInterventional
Ages18 Years to 48 Years
SexWomen only
Enrollment60 (estimated)
SponsorWashington University School of Medicine
Academic / other
Locations1 site (St Louis, Missouri)
StatusRecruiting
StartedMarch 17, 2025
Main results expectedSeptember 30, 2027
Study endsSeptember 30, 2028
Registry record updatedDecember 26, 2025
Trial IDNCT06549985 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are women aged 18-48 with a confirmed diagnosis of endometriosis and chronic pelvic pain lasting six months or more.

Probably not a fit

Patients who are currently pregnant, have severe physical impairments, or a history of psychiatric disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of the Peer Empowered Endometriosis Pain Support (PEEPS) program, an 8-week interdisciplinary group care initiative aimed at reducing pain interference in individuals aged 18 to 48 with endometriosis-associated chronic pelvic pain. Participants will engage in group sessions that incorporate integrative care strategies, including pelvic floor physical therapy and mindfulness techniques. The study compares outcomes between those receiving PEEPS alongside usual care and those receiving educational support with usual care, assessing improvements in pain, physical function, and quality of life through surveys and feedback mechanisms.

Why it matters

Potential benefit: If successful, this program could significantly reduce pain and improve the quality of life for patients suffering from endometriosis-related pain.

How similar studies have gone: Other studies have shown promise in using integrative group care approaches for chronic pain management, suggesting potential success for this novel program.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-48 years
* Operative confirmation of endometriosis
* Chronic pelvic pain (pain perceived to originate from the pelvis, not exclusively during menses, lasting ≥6 months)
* No plan to have surgery before or during the PEEPS cohort
* Able to attend at least six of the eight 2-hour weekly sessions on the Washington University campus
* Comfort reading and speaking English as groups and materials are in English

Exclusion Criteria:

* Currently pregnant
* Severe physical impairment (limiting yoga participation)
* History of hip or spine surgery given increased risk of harm and need for extensive activity modification
* Current or history of psychiatric disorder with psychosis in order to minimize risk of adverse mental health effects to participants
* Opioid use ≥ 5 days in the past 3 months, other than for the 6-week post-operative period
* History of surgical removal of bilateral ovaries

Where it's running

  • WashU Medicine
    St Louis, Missouri, United States
    Recruiting

Study contacts

  • Principal investigator: Whitney Ross, MD — Washington University School of Medicine
  • Study coordinator: Whitney Ross, MD
  • Email: ross.w@email.wustl.edu
  • Phone: 314-747-5470

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.