Sponsor or institution
Clinical trials and research at University of Oxford
As of November 12, 2026, Find a Trial lists 74 clinical trials run by University of Oxford that are recruiting, at sites in 39 countries (most in United Kingdom (56), Thailand (10), Laos (6)). 1 was first registered in the last 30 days. By phase: Phase 3 (4), Phase 4 (4), Phase 2 (4), Phase 1 (2). There are also 16 NIH-funded research projects at this institution, with $6.8 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 74Clinical trials
- 16NIH research projects
- 1New in 30 days
- 39Countries
Newest trials
All recruiting trials (74)
-
Newborn SMA Screening Service Evaluation
This project tests newborn SMA screening to see if it works well and is acceptable to families in the UK.
-
Prucalopride for low mood: testing a 5-HT4 receptor activator for cognition and sleep
This study tests whether prucalopride, a 5-HT4 receptor drug, can improve thinking and sleep in adults with low mood or major depressive disorder compared to a placebo.
-
Robotic-assisted tPA injection for retinal vein occlusion
This trial tests whether robot-assisted delivery of a clot-dissolving drug (tPA) into a blocked retinal vein can restore blood flow in people with central retinal vein occlusion.
-
Understanding heart artery disease using biomarkers and imaging in Oxford
Researchers in Oxford are testing how biomarkers and advanced imaging can help explain why some heart artery plaques are unstable and how this affects heart damage after a heart attack.
-
VTA real-time biofeedback with 7-Tesla MRI in depression
This study tests whether people with major depressive disorder can learn to modulate their brain's reward center (the VTA) using real-time feedback during 7-Tesla MRI sessions, to see if it changes mood and motivation.
-
Gut leakage in dengue: is the intestinal barrier affected during infection?
Researchers are studying whether dengue infection disrupts the gut barrier and if that contributes to severe disease in adults with dengue who are in hospital.
-
Probiotic Intake to See If It Helps Perimenopausal Women Think and Feel Better
We’re testing whether a multi-strain probiotic can improve emotional processing and cognitive function in perimenopausal women who have mood or cognitive concerns.
-
Closed-loop TMS to reduce tremor
This trial tries phase-locked transcranial magnetic stimulation (TMS) to reduce tremor in people with essential tremor or Parkinson's disease.
-
Wearable monitoring of motor development in babies and young children with spinal muscular atrophy detected at birth
This project will try wearing small motion sensors at home to see if they can track how babies and young children diagnosed with spinal muscular atrophy at birth move and develop, compared with healthy children.
-
Wearable monitoring to collect health data in people receiving transfusions for blood cancers
This project will try a wrist-worn accelerometer to see if continuous activity and symptom tracking helps doctors understand and support adults with MDS, AML or related blood cancers who need transfusions.
-
Hope Groups: parenting and mental health support for displaced Palestinian caregivers
This project will test whether Hope Groups help Palestinian caregivers displaced by war improve their mental health, strengthen parenting, and reduce violence toward children.
-
ParentText for Crisis: a WhatsApp chatbot for Palestinian caregivers in Jordan
A WhatsApp chatbot called ParentText for Crisis tests whether it can help Palestinian caregivers in Jerash Camp in Jordan feel less stressed, use healthier parenting techniques, and reduce violence toward their children.
-
How the placenta affects maternal and fetal health
This project will test whether tiny particles released by the placenta differ in pregnancies with pre-eclampsia, gestational diabetes, or fetal growth restriction compared with healthy pregnancies and non-pregnant women.
-
Digital sleep therapy to help people with fibromyalgia move more
This trial tests whether the Sleepio digital sleep program helps adults with fibromyalgia and insomnia sleep better, feel less afraid to move, and be more physically active.
-
Fluoxetine's effect on anger-related emotional responses in young adults
This study will test whether taking fluoxetine for one week changes how healthy 18–24-year-olds react to anger-related words, faces, memories, and frustrating tasks compared with a placebo.
-
Remote monitoring approach to track movement in young boys with Duchenne muscular dystrophy
A remote, watch-based method is being tested to see if it can accurately track how boys with Duchenne muscular dystrophy move, especially for ages 1-3.
-
Non-invasive anaemia test for pregnant people using ear imaging
This project tests a handheld imaging device called VITA to quickly detect anaemia and tell if it's caused by iron deficiency in pregnant people.
-
Environment, Pathogens, and Host Interactions in Melioidosis
This study follows people with melioidosis and matched healthy controls to see how the disease develops and what factors influence outcomes over a year in Thailand, Laos, and Cambodia.
-
Predicting who will get less pain after endometriosis surgery
This project will use brain scans and questionnaires to try to see if we can predict which people with severe endometriosis will have less pelvic pain after surgery.
-
Blocking orexin to see how it changes emotion, learning, and thinking
Researchers will test whether a single dose of the orexin blocker daridorexant changes emotional processing, aversive learning, and executive function in healthy adults aged 18–40.
-
Minimum infected mosquito bites needed to cause P. vivax malaria in Thai adults
This trial will test how many infected mosquito bites cause P. vivax malaria in healthy Thai adults to help build a safer vaccine-testing platform.
-
Sleep and mood after acquired brain injury: see if poor sleep links with neuropsychiatric symptoms
This study will test whether people who have had an acquired brain injury with poor sleep also have more neuropsychiatric symptoms than those with better sleep, over the first year after injury.
-
UK islet autoantibody registry for early Type 1 diabetes
This UK registry collects health and antibody information from people with one or more islet autoantibodies to track who develops Type 1 diabetes and to connect them with monitoring or prevention options.
-
LINX versus fundoplication for treating gastro-oesophageal reflux (GERD)
This trial will test whether the LINX magnetic ring or traditional fundoplication works better for adults with reflux (GERD) who need surgery.
-
Oxford study on the corpus luteum and placental health in early pregnancy
This observational study tests whether markers from the corpus luteum in early pregnancy can help predict who will develop preeclampsia.
-
Combination vaccines plus broadly neutralising antibodies for long-lasting HIV control
This trial will test whether combining HIV vaccines, short planned treatment interruptions, and broadly neutralising antibodies can help adults with well-controlled HIV keep the virus off ART for longer.
-
Effects of blocking the 5‑HT2A serotonin receptor on thinking and memory
This research will test whether a single 10 mg dose of pimavanserin (a 5‑HT2A serotonin blocker) changes memory, thinking, and learning in healthy adults aged 18–45.
-
Losartan plus activity scheduling for low positive mood
This study tests whether seven days of losartan taken with a short behavioural activation program helps people with low positive mood process positive information better than placebo.
-
Brief Cognitive Behaviour Therapy for adolescents with OCD
This study is testing a short, five-session therapy for teenagers with OCD to see if it can help them feel better and fit into regular mental health services, especially for those who also have autism.
-
Blood TB DNA test to track treatment progress
This project will test whether levels of TB-derived cell-free DNA in the blood can track treatment response in adults newly diagnosed with tuberculosis.
-
Using brain stimulation to improve stroke rehabilitation
This study is testing if a type of brain stimulation can help stroke survivors improve their arm and hand movements during rehabilitation.
-
Monitoring antimicrobial resistance in the Democratic Republic of Congo
This study is testing how well we can track antibiotic resistance in a hospital in Kinshasa, DRC, to better understand bacterial infections and improve treatment for patients.
-
Testing a home method for glucose tolerance in children with Type 1 Diabetes
This study tests a new way for kids with Type 1 Diabetes to check their blood sugar at home using a finger prick instead of a needle to see if it's easier and more comfortable.
-
Add CBD to antipsychotic treatment for first-episode psychosis to see if it helps more than placebo
This study tests whether adding cannabidiol (CBD) to ongoing antipsychotic treatment helps people with a first episode of psychosis who haven’t fully responded to their first antipsychotic, compared with a placebo.
-
Assessing the effectiveness of a new pneumococcal vaccine in healthy adults
This study is testing a new pneumococcal vaccine to see if it helps healthy adults aged 18-50 fight off an infection caused by a specific bacteria.
-
Hormone therapy's effect on liver disease in postmenopausal women
This study is testing if hormone replacement therapy can help postmenopausal women with liver disease by looking at how it affects liver fat and overall health.
-
Testing a new tuberculosis vaccine with a BCG challenge
This study is testing a new tuberculosis vaccine to see if it is safe and effective in people who have and haven't had the BCG vaccine before.
-
Structured antimicrobial review in ICUs to improve prescribing
This project tests a structured antimicrobial review in adult ICUs to see if it can be implemented successfully.
-
Abbreviated non-contrast MRI versus ultrasound for finding liver cancer in people with cirrhosis
We will test whether shorter MRI scans without contrast find liver cancer more reliably than routine ultrasound in adults with cirrhosis or otherwise at high risk.
-
Effects of nitrous oxide on emotional memory
This study is testing if breathing in nitrous oxide can change how young adults remember and feel about negative experiences.
-
Understanding lung immune responses and microbiome after tuberculosis exposure
This study looks at how the lungs' immune system and bacteria change in people who have recently been around someone with tuberculosis to help improve future vaccines.
-
Antiviral treatment for early RSV symptoms
This trial will test whether antiviral drugs—ribavirin, molnupiravir, or favipiravir—can lower viral levels and help adults 18–64 with early RSV recover faster than receiving no antiviral treatment.
-
Understanding impulsivity in Parkinson's patients with deep brain stimulation
This study is testing how deep brain stimulation affects impulsivity in people with Parkinson's disease to see if different settings can help reduce impulsive behavior.
-
Investigating the effects of citalopram on brain response to emotions
This study tests how the antidepressant citalopram affects the brain's response to emotions in healthy people by comparing brain scans after taking the medication or a placebo.
-
Deep brain stimulation for severe central post-stroke pain
This trial will try deep brain stimulation to see if it lowers severe, long-lasting central post-stroke pain in adults who haven't improved with other treatments.
-
Understanding how period pain in adolescents may lead to chronic pain
This study looks at how period pain in young women aged 11 to 20 might lead to long-term pain problems later on.
-
Understanding long-term heart health in women after hypertensive pregnancies
This study looks at why women who had high blood pressure during pregnancy might face heart problems later in life by comparing their health to women who had normal pregnancies.
-
Mass vaccination and drug administration for malaria in Bangladesh
This study is testing if giving a malaria vaccine and medication to whole villages in Bangladesh can reduce the spread of malaria compared to villages that don’t receive them.
-
Effects of diet on blood lipids and metabolism
This study is testing whether a low carbohydrate, high-fat diet or a high carbohydrate, low-fat diet can better improve blood fat levels and liver health in healthy adults.
-
Effects of different types of dietary fat on liver and heart health
This study tests how eating different types of fats affects liver and heart health in healthy adults over 28 days.
-
Establishing a Shigella infection model in Kenyan adults
This study is testing a new way to safely infect healthy Kenyan adults with Shigella to find the best dose for developing vaccines against this infection.
-
Fixed-dose combination of artemether-lumefantrine-amodiaquine for uncomplicated falciparum malaria
This trial will test whether a single fixed-dose combination of three antimalarials (artemether-lumefantrine-amodiaquine) works as well and is as safe and tolerable as standard two-drug combinations for people with uncomplicated Plasmodium falciparum malaria.
-
Effects of weight loss on heart function in obese patients with heart failure
This study tests if losing weight can help people with heart failure feel better and improve their heart function.
-
Effects of weight loss on heart health in obese patients with heart failure
This study tests if losing weight can help improve heart health in overweight or obese people with heart failure.
-
Observational study on psoriasis and its risk for arthritis
This study is trying to find out which adults with psoriasis are more likely to develop psoriatic arthritis so that steps can be taken to prevent it.
-
Exploring the impact of sleep on motor learning after stroke
This study looks at how sleep quality affects the recovery and movement skills of people who have had a stroke in their arm.
-
Understanding cardiovascular risks in young adults born to hypertensive pregnancies
This study is looking at the heart health of young adults in their 20s and 30s who were born to mothers with high blood pressure during pregnancy to see if it affects their risk of heart problems later on.
-
Comparing antiviral treatments for early symptomatic influenza
This study is testing different antiviral medications to see which ones work best for people with early symptoms of the flu who are otherwise healthy.
-
Tracking iron distribution in the body after intravenous iron infusion
This study is testing how intravenous iron infusions change iron levels in different parts of the body over time for people with iron deficiency.
-
COVID-19 vaccine immune responses in people being treated for tuberculosis
This project tests whether people being treated for tuberculosis make the same antibody and T‑cell responses to Pfizer, AstraZeneca, or Janssen COVID‑19 vaccines as healthy adults.
-
Early detection of liver cancer in patients with cirrhosis
This study is testing new ways to find liver cancer early in people with cirrhosis by looking at blood, urine, and other health information over four years.
-
Detecting small early liver cancer through patient follow-up
This study is testing if collecting blood, urine, and liver samples from patients with cirrhosis and small liver cancer can help find early signs of liver cancer to improve survival rates.
-
Improving sleep and learning for stroke survivors
This study is testing if a digital sleep program can help stroke survivors sleep better and improve their learning for rehabilitation.
-
Testing a form of folate in pregnancy for women with high blood pressure
This trial will test whether giving a biologically active folate (5‑MTHF) to pregnant women with pre-eclampsia or pregnancy-induced high blood pressure can raise a blood-vessel support molecule (BH4) and help mothers and babies.
-
Understanding the causes of Polycystic Ovary Syndrome
This study is trying to understand what causes Polycystic Ovary Syndrome (PCOS) and its related problems to find new treatment options for women with PCOS and reproductive issues.
-
Observational study on cardiovascular risk factors using non-invasive imaging
This study is trying to see if new imaging techniques can help doctors better understand and predict heart and metabolic diseases in patients getting CT scans.
-
Inoculation of infected blood cells to study Plasmodium vivax malaria
This study is testing if giving healthy Thai adults small doses of infected blood cells can help researchers learn more about malaria and find the best dose for future studies.
-
Testing antiviral treatments for early COVID-19 symptoms
This study is testing different antiviral treatments for people with early COVID-19 symptoms to see if they can help reduce the virus in those who are at low risk.
-
Characterizing liver cancer and chronic liver disease through sample collection
This study is trying to find early signs of liver cancer by collecting and comparing blood, urine, and liver samples from people with liver cancer and those with chronic liver disease.
-
Optimizing Tafenoquine Dosing for Malaria Treatment in Southeast Asia
This study is testing whether a higher dose of tafenoquine can work better than the standard dose for treating malaria in Southeast Asia.
-
Understanding causes and outcomes of febrile illness in rural South and Southeast Asia
This study is trying to find out what causes fevers and how they affect people living in rural areas of Laos, Myanmar, Thailand, and Bangladesh to help improve health care in those communities.
-
Investigating the long-term effects of COVID-19 on multiple organs
This study is trying to see how COVID-19 affects different organs in people who have recovered from the virus and how these effects impact their quality of life over time.
-
Evaluation of treatments to prevent death in hospitalized COVID-19 patients
This study tests different treatments to see if they can help hospitalized COVID-19 patients with pneumonia live longer and feel better.
-
Managing hypertension in young adults using echocardiography
This study is testing if using heart ultrasound scans along with regular check-up information can help doctors better manage high blood pressure in young adults aged 18 to 40.
NIH-funded research (16)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Optimizing tafenoquine dose to prevent relapse of vivax malaria in Asia
A study tests the best tafenoquine dose to prevent P. vivax malaria relapse in people in East Asia and Oceania.
-
Optimizing tafenoquine dose to prevent P. vivax malaria relapses in Asia
A study to find the best single-dose tafenoquine amount to prevent relapse of P. vivax malaria in people in East Asia and Oceania.
-
Optimizing tafenoquine dose to prevent malaria relapses in Southeast Asia
A study to find the best single-dose tafenoquine amount to prevent relapse of Plasmodium vivax malaria in people in East Asia and Oceania, including children and adults.
-
Understanding HIV-1 persistence in CD4+ T cells at the nanoscale
Aims to map how HIV hides in CD4+ T cells by looking at the cell’s structure at the tiniest scales.
-
Finding the right single-dose tafenoquine to stop relapsing vivax malaria
This project compares single-dose amounts of tafenoquine to find a safe dose that prevents relapses of Plasmodium vivax malaria in children and adults in Southeast Asia.
-
Immune differences between sexes in early life and childhood health
This NIH grant explores how boys and girls may develop their immune systems differently from birth through adolescence to tailor vaccines and treatments for better health.
-
Detecting Prenatal Alcohol Exposure with 3D Facial Imaging Across Ages
A project aims to use 3D facial imaging to identify individuals who were exposed to alcohol before birth, from infancy into adulthood, to help doctors screen and understand FASD better.
-
Finding genes that shape core autism traits
This project looks for genes that increase the chance of autism and explains how those genes change core autism traits in autistic people and their families.
-
Understanding how tafenoquine works in children to prevent malaria relapse
A pediatric study in the US and other settings will check how tafenoquine behaves in the body to prevent relapses of malaria in kids over 28 days old and at least 12 kg.
-
Improving single-dose tafenoquine to prevent relapses of vivax malaria
This project aims to find the best single-dose amount of tafenoquine to prevent relapses of Plasmodium vivax malaria in people in Southeast Asia, including children and adults.
-
Understanding Genetic Differences in Developing Brain Cells
This research looks at how genetic differences affect brain development from before birth through teenage years, hoping to understand conditions like Alzheimer's and other brain disorders.
-
How immune responses differ between boys and girls from before birth through adolescence
This project looks at how babies, children, and teens of different sexes respond to vaccines and infections so treatments and vaccines can be better matched to boys and girls.
-
Targeting protein degradation to treat advanced childhood tumors
This study is working on new ways to treat children with tough-to-treat brain tumors by focusing on specific proteins that help these cancers grow, using cutting-edge techniques to find better treatments that can improve their chances of recovery.
-
Investigating how HIV-1 integrates into T-lymphocytes
This study is looking at how the HIV-1 virus connects its genetic material to important immune cells in your body, which could help us find new ways to treat HIV and improve health for people living with the virus.
-
Identifying genes that increase the risk of autism and their effects on the disorder
This study is looking at the genes that might play a role in autism to help us understand the condition better, and it's for families and individuals affected by autism who want to learn more about how genetics can influence their experiences.
-
Finding the best dose of tafenoquine to cure malaria caused by Plasmodium vivax in Southeast Asia
This study is looking to find the best dose of tafenoquine, a medicine for treating malaria, especially for kids and pregnant women, to help prevent the illness from coming back and make it easier for patients to stick to their treatment.
Quick answers
How many clinical trials run by University of Oxford are recruiting right now?
74, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 39 countries. The most sites are in United Kingdom (56 trials), Thailand (10 trials), Laos (6 trials), Nepal (3 trials), Italy (3 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 4, Phase 4: 4, Phase 2: 4, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.