Clinical trial Recruiting at 1 site Observational Ages 18 and up

Observational study on psoriasis and its risk for arthritis

Official title: Determining Risk Factors for the Development of Psoriatic Arthritis (PsA) Amongst People Living With Psoriasis: A Patient-driven On-line Prospective European Observational Cohort

Run by University of Oxford · NCT05858528 · Data updated 2026-11-12

This study is trying to find out which adults with psoriasis are more likely to develop psoriatic arthritis so that steps can be taken to prevent it.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment25000 (estimated)
SponsorUniversity of Oxford
Academic / other
Locations1 site (Oxford, Oxfordshire)
StatusRecruiting
StartedJune 27, 2023
Main results expectedJune 30, 2026
Study endsJune 30, 2026
Registry record updatedApril 2, 2025
Trial IDNCT05858528 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with a self-reported diagnosis of skin psoriasis.

Probably not a fit

Patients who already have a pre-existing diagnosis of psoriatic arthritis will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The HIPPOCRATES Prospective Observational Study aims to identify patients with psoriasis who are at risk of developing psoriatic arthritis. Conducted across Europe, this study involves adults with psoriasis who will complete questionnaires every six months to monitor their condition. The research is led by the University of Oxford in collaboration with University College Dublin, focusing on understanding the progression from psoriasis to psoriatic arthritis. The ultimate goal is to prevent the onset of arthritis in at-risk individuals.

Why it matters

Potential benefit: If successful, this study could lead to early interventions that prevent the development of psoriatic arthritis in patients with psoriasis.

How similar studies have gone: Other studies have shown promise in identifying risk factors for psoriatic arthritis, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult ≥18 years
* Self-reported diagnosis of skin psoriasis (any form)
* Participant is willing and able to give informed consent for participation in the study and complete data in one of the HPOS languages

Exclusion Criteria:

• Pre-existing diagnosis of PsA

Where it's running

  • Oxford University Hospital NHS Foundation Trust
    Oxford, Oxfordshire, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.