Observational study on cardiovascular risk factors using non-invasive imaging

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Oxford Risk Factors And Non-Invasive Imaging Study (ORFAN) is a prospective, multi-centre observational study aimed at developing and validating novel biomarkers for cardiometabolic diseases. It will collect CT scans, biological samples, and clinical outcomes data from unselected patients undergoing various CT scans at participating centers. By linking imaging data with patient demographics and clinical information, the study seeks to enhance diagnosis and risk prediction through advanced image analysis algorithms. Additionally, it will track disease progression and outcomes through follow-up scans and data collection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Inclusion Criteria for study Arms 1, 2 and 3:

* Participant is willing and able to give informed consent for participation in the study.
* Male or Female, aged 18 -99 years.

Inclusion Criteria for study Arm 4:

• Male or Female, aged 18 -99 years.

Exclusion Criteria:

Exclusion Criteria for Study Arms 1, 2 and 3:

* Unable or unwilling to consent
* Active cancer

Exclusion Criteria for Study Arm 4:

* Participation in Study Arms 1, 2 or 3
* Existing opt-out from use of data for research purposes

Where it's running

• Valleywise Health
  Phoenix, Arizona, United States Recruiting
• Yale University, School of Medicine
  New Haven, Connecticut, United States Recruiting
• Bridging Medical Silos
  Tampa, Florida, United States Recruiting
• Emory University
  Atlanta, Georgia, United States Recruiting
• Midwest Heart & Vascular Specialists LLC
  Kansas City, Kansas, United States Recruiting
• St Luke's Hospital
  Kansas City, Kansas, United States Recruiting

Study contacts

• Principal investigator: Charalambos Antoniades, Prof — University of Oxford
• Study coordinator: Kenneth Chan, Dr
• Email: kenneth.chan@cardiov.ox.ac.uk

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.