Exploring the impact of sleep on motor learning after stroke
Official title: Investigating Consolidation of Motor Learning in the Context of Recovery After Stroke
Run by University of Oxford · NCT05746260 · Data updated 2026-11-12
This study looks at how sleep quality affects the recovery and movement skills of people who have had a stroke in their arm.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | University of Oxford Academic / other |
| Locations | 1 site (Oxford) |
| Status | Recruiting |
| Started | March 1, 2023 |
| Main results expected | March 2027 |
| Study ends | March 2027 |
| Registry record updated | November 19, 2024 |
| Trial ID | NCT05746260 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who have experienced a stroke affecting the upper limb within the past month.
✕Probably not a fit
Patients with other neurological conditions affecting movement, such as Parkinson's disease or Multiple Sclerosis, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the relationship between sleep disruption and clinical motor outcomes in individuals recovering from stroke affecting the upper limb. It aims to determine if variations in sleep quality during the sub-acute phase of stroke influence motor learning consolidation and subsequent recovery. Participants will be recruited within one month of stroke onset, and their sleep measures, demographic factors, and other relevant covariates will be analyzed to understand their impact on motor outcomes. The study employs a longitudinal design to track changes over time.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation strategies that enhance recovery outcomes for stroke patients by addressing sleep quality.
How similar studies have gone: While the relationship between sleep and recovery after stroke is being explored, this specific approach focusing on motor learning consolidation is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the study OR a positive opinion from a consultee is provided by a family member or carer (relative or friend) willing to provide personal consultee (PC) advice * Aged 18 years or above * Within 1 month of onset of stroke affecting the upper limb as confirmed by clinical diagnosis Exclusion Criteria: * Other neurological condition affecting movement (such as Parkinson's disease, Multiple Sclerosis)
Where it's running
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Wellcome Centre for Integrative Neuroimaging (WIN)
Oxford, United Kingdom Recruiting
Study contacts
- Principal investigator: Heidi Johansen-Berg, Professor — University of Oxford
- Study coordinator: Melanie K Fleming, Dr
- Email: melanie.fleming@ndcn.ox.ac.uk
- Phone: 01865 611 461
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
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Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
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Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
-
Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.