Exploring the impact of sleep on motor learning after stroke

Investigating Consolidation of Motor Learning in the Context of Recovery After Stroke

Observational University of Oxford · NCT05746260

This study looks at how sleep quality affects the recovery and movement skills of people who have had a stroke in their arm.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Oxford Academic / other
Locations1 site (Oxford)
Trial IDNCT05746260 on ClinicalTrials.gov

What this trial studies

This observational study investigates the relationship between sleep disruption and clinical motor outcomes in individuals recovering from stroke affecting the upper limb. It aims to determine if variations in sleep quality during the sub-acute phase of stroke influence motor learning consolidation and subsequent recovery. Participants will be recruited within one month of stroke onset, and their sleep measures, demographic factors, and other relevant covariates will be analyzed to understand their impact on motor outcomes. The study employs a longitudinal design to track changes over time.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have experienced a stroke affecting the upper limb within the past month.

Not a fit: Patients with other neurological conditions affecting movement, such as Parkinson's disease or Multiple Sclerosis, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation strategies that enhance recovery outcomes for stroke patients by addressing sleep quality.

How similar studies have performed: While the relationship between sleep and recovery after stroke is being explored, this specific approach focusing on motor learning consolidation is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participant is willing and able to give informed consent for participation in the study OR a positive opinion from a consultee is provided by a family member or carer (relative or friend) willing to provide personal consultee (PC) advice
* Aged 18 years or above
* Within 1 month of onset of stroke affecting the upper limb as confirmed by clinical diagnosis

Exclusion Criteria:

* Other neurological condition affecting movement (such as Parkinson's disease, Multiple Sclerosis)

Where this trial is running

Oxford

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeRehabilitationMotor Consolidation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.