Closed-loop TMS to reduce tremor

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study applies closed-loop, phase-locked transcranial magnetic stimulation that times magnetic pulses to the phase of tremor-related brain activity in order to suppress pathological oscillations. Participants with essential tremor or Parkinson's disease will attend non-invasive TMS sessions at the Oxford Center for Integrative Neuroimaging, where tremor is monitored in real time to guide stimulation timing. The protocol excludes individuals with contraindications to brain stimulation and focuses on tremor that impacts upper-limb function. Effectiveness will be measured by changes in tremor amplitude and functional measures before and after stimulation sessions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* having either essential tremor or Parkinson's disease

Exclusion Criteria:

* contraindications to brain stimulation

Where it's running

• Oxford Center for Integrative Neuroimaging
  Oxford, Oxfordshire, United Kingdom Recruiting

Study contacts

• Study coordinator: Charlotte Stagg J Professor of Human Neurophysiology, MBBS
• Email: charlotte.stagg@ndcn.ox.ac.uk
• Phone: 01865 222734

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.