Remote monitoring approach to track movement in young boys with Duchenne muscular dystrophy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study explores a new remote testing approach using ankle-worn devices to measure movement in very young boys with Duchenne muscular dystrophy. It focuses on toddlers who cannot easily complete traditional motor tests, aiming to capture reliable movement data outside clinic visits. The study is led by the University of Oxford and compares children with DMD to healthy controls to understand baseline motion and disease-related changes. It does not specify a treatment, but seeks to improve how outcomes are measured in early-stage research and future trials.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Participant with DMD:

* Male
* Aged 1-3 years old
* Ambulant (walking 10m independently)
* Genetically confirmed diagnosis of DMD
* Parent(s)/legal guardian(s) able and willing to provide written informed consent for the child to participate in the study
* Parent(s)/legal guardian(s) able and willing to participate in the study

Parent/legal guardian of participant with DMD:

* Aged 18 years or more
* Legal carer of the patient diagnosed with DMD
* Willingness to follow study procedures and assist with remote assessments, as assessed by the research team
* Willingness to sign the consent form
* Ability to understand all the information with regards to the study, as assessed by the research team

Healthy Control participant:

* Male
* Aged 1-3 years old
* Ambulant (walking 10m independently)
* Parent(s)/legal guardian

Exclusion Criteria:

Participant with DMD:

* Limb surgery/trauma (within 6 months)
* Significant comorbid chronic or acute conditions affecting motor function (within 3 weeks)
* Prematurity (born \<37 weeks' gestation)
* Oral corticosteroids to treat DMD (before enrolment)
* Enrolment in therapeutic clinical trials
* Any comorbidity which could limit their ability to complete the study assessments (according to the investigator's clinical judgement)

Healthy Control participant:

* Limb surgery/trauma (within 6 months)
* Significant comorbid chronic condition affecting motor function
* Significant acute condition affecting motor function (within 3weeks of enrolment)
* Prematurity (born \<37 weeks' gestation)
* Neurodevelopmental concerns or delay in acquisition of WHO developmental milestones.
* Any comorbidity which could limit their ability to complete the study assessments (according to the investigator's clinical judgement).

Where it's running

• Oxford University
  Oxford, United Kingdom Recruiting

Study contacts

• Study coordinator: Fiona Moultrie
• Email: fiona.moultrie@paediatrics.ox.ac.uk
• Phone: +44 (0)1865 618799

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.