Gestational weight gain and outcomes after preconception GLP-1 receptor agonist use

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study is a prospective observational cohort that will enroll about 400 pregnant women at or before 20 weeks gestation. It will compare gestational weight gain and obstetric outcomes between those with GLP-1RA exposure in the three years before conception and those without exposure. Participants will complete questionnaires at baseline, late pregnancy, and postpartum timepoints to collect medication history, eating behaviors, and other factors. No treatment will be given as part of the study, and the aim is to understand associations between prior GLP-1RA use and pregnancy outcomes. The research is conducted at the University of Kansas Medical Center and involves follow-up through 6 months postpartum.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult women
* Less than or equal to 20 weeks gestation at first visit
* English speaking

Exclusion Criteria:

* \<18 years at time of initial visit
* Type 2 diabetes
* History of bariatric surgery
* Multiple gestation
* Cannot consent for themselves
* Cannot read and speak English
* Incarcerated

Where it's running

• University of Kansas Medical Center
  Kansas City, Kansas, United States Recruiting

Study contacts

• Study coordinator: Molly Fain
• Email: mfain3@kumc.edu
• Phone: 913-588-5478

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.