5-week combined aerobic and strength exercise after bariatric surgery
Effect of a Concurrent Exercise Program on Muscle Quality, Body Composition, Functional Response, and Quality of Life in Individuals Undergoing Bariatric Surgery
This test tries a 5-week combined aerobic and strength exercise program for adults recovering from sleeve gastrectomy or gastric bypass to see if it improves muscle quality, body composition, physical function, and quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Universidad Autónoma de Chile Academic / other |
| Locations | 1 site (Santiago, Santiago Metropolitan) |
| Trial ID | NCT07423780 on ClinicalTrials.gov |
What this trial studies
This single-center, prospective, non-randomized controlled trial will enroll 84 adults (18–60 years) who had sleeve gastrectomy or Roux-en-Y gastric bypass and have a medical indication for metabolic rehabilitation. Participants are allocated to an intervention group that completes a supervised concurrent (aerobic + resistance) exercise program twice weekly for 5 weeks or to a control group receiving usual care without a structured exercise program. Outcomes include rectus femoris muscle quality as the primary endpoint, with secondary measures of body composition, functional response, quality of life, and adherence-related dose-response effects. Assessments occur at baseline (postoperative week 4) and 7 weeks later (after the 5-week intervention plus one week of rest).
Who should consider this trial
Good fit: Adults aged 18 to 60 who underwent sleeve gastrectomy or Roux-en-Y gastric bypass at Clínica BUPA Santiago and have a medical indication for metabolic rehabilitation are eligible, including those with conditions like insulin resistance, dyslipidemia, hypertension, or hypothyroidism.
Not a fit: Patients with type 1 or type 2 diabetes, severe musculoskeletal disorders limiting ambulation, prior cardiovascular events, severe cardiorespiratory disease, dependence on supplemental oxygen, or current bariatric surgery complications are excluded and unlikely to benefit from this program.
Why it matters
Potential benefit: If successful, the program could help preserve or improve muscle quality and physical function during the early recovery period after bariatric surgery, potentially improving recovery and quality of life.
How similar studies have performed: Longer and later-starting exercise programs after bariatric surgery have shown benefits for muscle mass and function, but short-term concurrent programs begun in the early postoperative phase are less well tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria * Voluntarily agree to participate and sign informed consent. * Men and women aged 18 to 60 years. * Have undergone bariatric surgery (sleeve gastrectomy or gastric bypass) at BUPA Clinic Santiago. * Have a medical indication for metabolic rehabilitation. * May present associated comorbidities such as insulin resistance syndrome, dyslipidemia, arterial hypertension, and/or hypothyroidism. Exclusion Criteria * Diagnosis of type 1 or type 2 diabetes mellitus. * Severe musculoskeletal disorders that impair ambulation or limit participation in the exercise program. * History of a cardiovascular event. * Severe cardiorespiratory diseases that significantly reduce physical capacity or cause dyspnea at rest or with minimal exertion. * Dependence on supplemental oxygen. * Bariatric surgery-related complications, including: * Staple line leak or fistula * Hemorrhage/bleeding * Stenosis or gastric narrowing/stricture * Intra-abdominal abscess * Hypersensitivity (as clinically determined). * Hepatic and/or renal insufficiency.
Where this trial is running
Santiago, Santiago Metropolitan
- Clínica BUPA, Santiago — Santiago, Santiago Metropolitan, Chile (Recruiting)
Study contacts
- Principal investigator: María José Pabst Pérez, MSc — Universidad Autónoma de Chile
- Study coordinator: María José Pabst Perez, MSc
- Email: majose.pabst@gmail.com
- Phone: +56950023025
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.