Myokines in metabolic and endocrine diseases linked to sarcopenia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-center observational study will measure how common sarcopenia and sarcopenic obesity are among patients with metabolic or endocrine conditions and explore whether myokines relate to muscle loss. It will evaluate the potential of myokines to act as biomarkers or contributors to sarcopenia in this population. Interventions include GLP-1 receptor agonists as part of observational assessment. Participants will be adults with metabolic or endocrine diseases, excluding those with myopathy, high-dose systemic steroids, recent cancer, or other factors limiting protocol adherence. The study is led by Cliniques universitaires Saint-Luc - Université Catholique de Louvain at a single site in Brussels, Belgium.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Metabolic or endocrine disease

Exclusion Criteria:

* Known myopathy
* Systemic steroid use (\> 1 mg/kg hydrocortisone) or exogenous Cushing's syndrome
* Psychological, family, sociological or geographical conditions that could potentially limit compliance with the study protocol
* History of cancer within the five years prior to the study or Cushing's syndrome due to ACTH-secreting tumor

Where it's running

• Cliniques Universitaires Saint-Luc
  Woluwe-Saint-Pierre - Sint-Pieters-Woluwe, Belgium Recruiting

Study contacts

• Study coordinator: Laura Orioli, MD, PhD
• Email: laura.orioli@saintluc.uclouvain.be
• Phone: +32494507621

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.