Predicting Weight Loss After Obesity Treatments

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study looks for factors that predict weight loss response to obesity treatments, including drugs or surgery, in adults with obesity. It also aims to understand the cognitive and biological processes that may mediate response and how eating behavior might influence outcomes. Researchers will collect data from participants evaluated for bariatric surgery or pharmacological therapy and analyze which characteristics are linked to better or worse weight loss. The goal is to help tailor care pathways based on individual predictors. The study is conducted at Cliniques Universitaires Saint-Luc in Brussels and led by Université Catholique de Louvain.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Age between 18 and 65 years
* Obesity, with bariatric surgery indicated after a multidisciplinary evaluation in case of surgical treatment.
* Good physical and mental health, enabling informed consent.
* French speaker

Exclusion criteria:

* Legal protection
* Pregnancy or breastfeeding
* History of bariatric surgery (except gastric banding, provided it was removed more than five years ago).
* Acute or progressive chronic disease
* Alcohol consumption of more than 20 g/day
* Inflammatory bowel disease;
* Digestive autonomic diabetic neuropathy.
* Consumption of dietary supplements (stanols, probiotics, prebiotics or omega-3).
* Following a vegan or gluten-free diet or being lactose intolerant.
* Fibre consumption \>30 g/day
* Recent change in antidiabetic medication within the past 3 months.

Where it's running

• Cliniques Universitaires Saint-Luc
  Brussels, Brussels Capital, Belgium Recruiting

Study contacts

• Study coordinator: Pr Amandine Everard, Professor
• Email: amandine.everard@uclouvain.be
• Phone: + 32 (0)2 436 22 10

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.