Integrated Traditional Chinese and Western medicine care for adults with obesity
Real-World Prospective Registry Study of Integrated Traditional Chinese and Western Medicine Interventions in Patients With Obesity
This project will try combining traditional Chinese medicine and Western medical care in adults with obesity to see how well that combination works in everyday clinical practice.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Hubei Hospital of Traditional Chinese Medicine Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT07448090 on ClinicalTrials.gov |
What this trial studies
This is a multicenter, prospective, observational registry enrolling at least 10,000 adults with obesity from urban and rural populations in China. Participants receive routine clinical care without assigned interventions while researchers collect electronic medical records, laboratory tests, imaging, and lifestyle information. The registry will document real-world integrated TCM and Western medicine management and compare outcomes across age groups, disease stages, and TCM constitution types. Health economic analyses and disease progression pattern analyses will be performed to identify key prevention and treatment points.
Who should consider this trial
Good fit: Adults aged 18 or older with BMI ≥ 28.0 kg/m2, weight fluctuation ≤ 5% in the prior 3 months, able to consent and comply with follow‑up, and without severe organ disease or secondary/iatrogenic obesity are appropriate candidates.
Not a fit: Patients with secondary or iatrogenic obesity, significant heart/liver/lung/kidney/brain or blood disorders, pregnant or breastfeeding women, or those the investigator deems unsuitable are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the project could help personalize obesity care by identifying effective, safe, and cost‑effective combinations of TCM and Western treatments.
How similar studies have performed: Smaller clinical and observational studies have suggested benefits from combining TCM and Western approaches for obesity, but high‑quality large-scale real-world evidence remains limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 18 years and above, gender not restricted; 2. Weight fluctuation within the last 3 months is ≤ 5% and BMI is ≥ 28.0 kg/m2; 3. Good compliance, willing to follow the follow-up principles; 4. Agree to sign the informed consent form. Exclusion Criteria: 1. Co-existing severe diseases of the heart, liver, lungs, kidneys, brain, blood, neuro-psychiatric system, or other vital organs. 2. Secondary obesity (obesity attributable to another clearly diagnosed disorder, e.g., hypothalamic or pituitary inflammation, tumours or trauma, Cushing's syndrome, hypothyroidism, hypogonadism, polycystic ovary syndrome, etc.). 3. Iatrogenic obesity (obesity resulting from drugs or therapeutic interventions administered for other conditions). 4. Pregnant or lactating women. 5. Subjects whom the investigator deems unsuitable for participation in this study.
Where this trial is running
Wuhan, Hubei
- Hubei Provincial Hospital of Traditional Chinese Medicine — Wuhan, Hubei, China (Recruiting)
Study contacts
- Principal investigator: ChenGang ChenGang, Doctor — Hubei College of Traditional Chinese Medicine
- Study coordinator: ChenGang Professor ChenGang, Doctor
- Email: 250149875@qq.com
- Phone: +86 17720376888
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.