Respiratory function and inspiratory muscle training for adults with obesity
Functional Respiratory Tract Dysfunctions in Individuals With Obesity Undergoing Experimental Inspiratory Muscle Training.
This will test whether inspiratory muscle training can improve breathing and lower inflammation in adults aged 30–60 with obesity (BMI ≥30).
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 30 Years to 60 Years |
| Sex | All |
| Sponsor | Wroclaw University of Health and Sport Sciences Academic / other |
| Locations | 1 site (Wroclaw, Dolny Śląsk) |
| Trial ID | NCT07307417 on ClinicalTrials.gov |
What this trial studies
Adults with obesity will be enrolled at a single center and randomly assigned to receive inspiratory muscle training or a placebo IMT protocol. Respiratory mechanics will be measured using techniques such as the forced oscillation technique, and inflammatory markers will be tracked to link breathing changes with inflammation. Participants with active respiratory disease requiring medication or other major medical exclusions are not eligible. The protocol focuses on supervised, repeated IMT sessions compared with a sham device to determine functional and inflammatory effects.
Who should consider this trial
Good fit: Ideal candidates are men and women aged 30–60 with a BMI of 30 kg/m2 or higher who can attend in-person visits and give informed consent.
Not a fit: People with respiratory diseases that require pharmacological treatment, those with acute illnesses or certain implants (pacemaker, electronic or metal implants), pregnant individuals, or those unable to cooperate are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, IMT could improve respiratory function and reduce inflammation in people with obesity, potentially easing breathlessness and lowering risk of ventilation problems.
How similar studies have performed: Similar inspiratory muscle training approaches have shown improvements in respiratory muscle strength in other populations, but evidence specifically showing reduced inflammation or clear clinical benefit in obesity is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosed obesity, BMI equal to or greater than 30 kg/m2 * age between 30 and 60 (women and men), * consent of the subject. Exclusion Criteria: * respiratory diseases requiring pharmacological treatment, * acute illness that may affect the training programme: e.g. infection, renal failure, * mental impairment preventing cooperation, * mental disorders preventing contact and cooperation with the patient, * pacemaker, * pregnancy * implanted electronic * medical implants * epilepsy * metal implants.
Where this trial is running
Wroclaw, Dolny Śląsk
- Wroclaw University of Health and Sport Sciences — Wroclaw, Dolny Śląsk, Poland (Recruiting)
Study contacts
- Principal investigator: Dariusz Kałka, prof. — Wroclaw University of Health and Sport Sciences
- Study coordinator: Paulina Okrzymowska, phD
- Email: paulina.okrzymowska@awf.wroc.pl
- Phone: +48 71 347 3520
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.