Hydration Support to Help GLP-1 Therapy Side Effects

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study enrolls adults aged 18 to 60 who have just begun a GLP-1 RA and are fluent in English. Over a one-week run-in and 16-week intervention, participants are assigned to Hydration Plus or Control to examine feasibility and potential reductions in side effects, side effect burden, and treatment discontinuation. Researchers will monitor hydration biomarkers, adherence to the protocol, and participant feedback to gauge preliminary efficacy. The trial aims to determine whether a hydration-focused approach is practical and potentially beneficial for patients beginning GLP-1 RA therapy. The lead sponsor is SUNY Buffalo with NIH collaboration, and the study is located at SUNY Buffalo South Campus.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18-60
* Recently prescribed a GLP-1RA (within one week of prescription)
* Fluent in English
* Willing to complete the study protocol

Exclusion Criteria:

* Children and adults \> 60 years of age
* Those not taking a GLP-1RA
* Those who have been on a GLP-1RA longer than one week
* Not fluent in English
* Those who are pregnant or planning on becoming pregnant during the duration of the study
* Unwilling to comply with study protocol
* People with cardiac implants

Where it's running

• State University of New York at Buffalo, South Campus
  Buffalo, New York, United States Recruiting

Study contacts

• Principal investigator: Katherine N Balantekin, PhD, RD — University at Buffalo

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.