Condition

Myocardial Ischemia clinical trials and research

• 26Clinical trials
• 12NIH research projects
• 18Countries

Newest Myocardial Ischemia clinical trials

All recruiting trials (26)

• Pediatric Cardiac Oxygenation Monitoring During Open-Heart Surgery

  This study tests whether the SpectroCor Tissue Oxygenation Monitor and its Sensor can track heart tissue oxygen levels in children undergoing open-heart surgery.

  Recruiting Spectrocor · Helsinki, Uusimaa · NCT07785141

• 4-electrode tablet ECG vs standard 12-lead ECG: see which is faster and clearer

  This study tests whether the 4-electrode DigitalCardio tablet ECG can record a full ECG faster and with comparable trace quality to a standard 12-lead ECG in adults with heart conditions.

  Recruiting Clinique Bizet · Paris and 1 other locations · NCT07732283

• Magnetocardiography in people with chest pain and non-obstructive heart arteries

  This study uses magnetocardiography to see if it can help identify non-obstructive myocardial ischemia in adults with acute chest pain.

  Recruiting Qilu Hospital of Shandong University · Jinan, Shandong · NCT07657546

• AI-assisted cardiac CT to predict coronary artery disease risk

  This project will try using AI-enhanced heart CT scans to better predict future coronary events in adults who are already getting a clinical cardiac CT.

  Recruiting University of Galway · Galway · NCT07577609

• COMA.NET: Targeted treatment for coronary microcirculation problems

  This trial will test whether tailoring medicines based on intracoronary microvascular testing improves quality of life for people with ischemia but no large artery blockages.

  Recruiting Medical University of Bialystok · Bialystok · NCT07498231

• Coronary CT angiography–guided calcium modification during PCI for calcified coronary artery disease

  This study will see if using CT angiography to plan calcium treatment before stenting helps people with flow-limiting, calcified coronary artery disease have better stent results and faster procedures compared with the usual ultrasound-guided PCI while keeping similar safety.

  Recruiting at 10 sites Fundación EPIC · Boston, Massachusetts and 14 other locations · NCT07286578

• Freesolve resorbable magnesium scaffold vs. Xience stent for up to two new heart artery lesions

  This trial tests whether the Freesolve resorbable magnesium scaffold works as well as the Xience drug-eluting stent for treating up to two new coronary artery lesions in adults.

  Recruiting at 3 sites Teleflex · Washington D.C., District of Columbia and 2 other locations · NCT07258290

• Detecting heart muscle injury during below-knee leg surgery with peripheral nerve block

  This will test whether measuring high‑sensitive troponin I during and after below‑knee leg surgery can detect heart muscle damage in adults receiving peripheral nerve blocks.

  Recruiting Ankara City Hospital Bilkent · Ankara · NCT07241572

• Software that analyzes heart CT scans to detect coronary artery disease

  This project will test a new software that uses past coronary CT scans to see if it can accurately find blockages and predict which patients might need procedures.

  Recruiting at 4 sites Instituto de Investigación Biomédica de Salamanca · Villeurbanne and 3 other locations · NCT06977295

• Surgery to treat myocardial bridge in coronary arteries

  This study tests if a special heart surgery can help people with symptoms from a condition called myocardial bridge feel better and improve their quality of life.

  Recruiting Xi'an International Medical Center Hospital · Xi'an, Shaanxi · NCT06857838

• Evaluating the Prognostic Value of Stress Echocardiography

  This study is testing if positive stress echocardiography results can help predict serious heart problems in people with coronary artery disease or reduced blood flow to the heart.

  Recruiting Hellenic Society of Cardiology · Athens, Attica · NCT06839755

• Improving diagnosis of anomalous coronary arteries

  This study is testing a new online tool that uses advanced technology to help doctors better diagnose and understand the risks for patients with unusual heart artery conditions.

  Recruiting IRCCS Policlinico S. Donato · San Donato Milanese, Italia · NCT06705751

• Inspiratory muscle training for heart disease patients after angioplasty

  This study tests whether a special breathing exercise program can help heart disease patients feel better and exercise more after having angioplasty.

  Recruiting University of Cadiz · Málaga · NCT06681740

• Comparing heart imaging techniques for coronary artery disease

  This study is testing if a new heart imaging method can better identify problems in patients suspected of having coronary artery disease compared to a traditional imaging technique.

  Recruiting Semmelweis University · Budapest, Budapest · NCT06670768

• Single versus dual antiplatelet therapy after drug-coated balloon angioplasty in elderly or high-bleeding-risk patients

  This study tests whether taking one antiplatelet medicine is as safe and causes less bleeding than taking two medicines for people aged 75 or older, or adults at high bleeding risk, after drug-coated balloon angioplasty for coronary artery disease.

  Recruiting Fondazione Ricerca e Innovazione Cardiovascolare ETS · Milan, MI · NCT06535568

• Using a smartphone device to record 12-lead ECGs for heart attack diagnosis

  This study is testing a smartphone device that records heart activity to see if it can help doctors quickly diagnose heart attacks in adults who come to the emergency room with chest pain.

  Recruiting at 2 sites AliveCor · Rochester, Minnesota and 3 other locations · NCT06271577

• Assessing treatment strategies for chronic coronary syndrome

  This study is testing whether getting heart surgery sooner or sticking with medication helps people with chronic coronary syndrome feel better after three months.

  Recruiting Gødstrup Hospital · Herning, Central Jutland · NCT05865600

• Registry collecting data on patients undergoing heart artery procedures

  This study is collecting information from patients who are having heart artery procedures to see how they do during and after their treatment.

  Recruiting Federico II University · Naples · NCT05248165

• Effects of lung cancer surgery on heart function and electrocardiograms

  This study is testing how modern lung cancer surgery affects heart function and heart rhythms in adults to see what changes happen during and after the surgery.

  Recruiting Tampere University Hospital · Tampere, Pirkanmaa · NCT05094843

• Evaluating the effectiveness and safety of Synergy XD and Megatron stents

  This study is testing how well and safely the Synergy XD and Megatron stents work for people with coronary artery disease compared to other stents in real-life situations.

  Recruiting at 19 sites Asan Medical Center · Anyang and 22 other locations · NCT05044273

• Registry to optimize management and outcomes for patients with acute myocardial infarction

  This study is looking at how well different treatments work for patients who have had a heart attack and received a specific procedure called PCI, to see what helps them recover better.

  Recruiting Luzerner Kantonsspital · Lucerne · NCT04988672

• Investigating heart disease risk factors in psoriasis patients

  This study is trying to see if certain heart-related markers can help predict heart disease risk in people with psoriasis.

  Recruiting Herlev and Gentofte Hospital · Hellerup, Copenhagne · NCT04950218

• Understanding Myocardial Ischemia Without Blocked Arteries

  This study is trying to understand heart problems caused by non-blocked arteries in patients with chest pain to see how well different treatments work over five years.

  Recruiting Hospital San Carlos, Madrid · Madrid · NCT04827498

• Evaluating regadenoson for pediatric patients with heart conditions

  This study is testing if regadenoson is safe for kids and infants with heart conditions who need a special heart test.

  Recruiting at 2 sites Phase 1/2 GE Healthcare · Paris and 4 other locations · NCT04604782

• Using exercise testing to diagnose heart blood flow issues

  This study is testing if a special exercise test can help doctors find heart blood flow problems by comparing its results to a different type of heart scan.

  Recruiting Kuopio University Hospital · Kuopio · NCT04067700

• Using bright light therapy to improve outcomes in cardiac surgery patients

  This study tests if bright light therapy can help heart surgery patients by reducing heart damage and improving their recovery.

  Recruiting University of Colorado, Denver · Denver, Colorado · NCT03822949

NIH-funded research (12)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Targeting endothelial epsins to help the heart heal after a heart attack

  Researchers are studying a protein in blood vessels to find ways to improve blood flow and heart repair after a heart attack.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11380819

• Role of miR98 in heart injury during late pregnancy

  A study in pregnant people or models will look at how a tiny molecule called miR98 affects heart injury after a heart attack during the third trimester.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11367676

• Role of LonP1 in protecting the heart from ischemia-reperfusion injury

  A study to see if boosting a mitochondrial protein called LonP1 can reduce heart damage after a blocked artery is opened in people who have a heart attack.

  NIH research West Virginia University · Morgantown, United States · NIH-11345782

• Helping the heart recover after a heart attack by targeting blood vessel cell proteins (epsins)

  This project tests whether blocking a protein called epsins in the cells that line blood vessels can help the heart heal better after a heart attack.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11134643

• How metabolic syndrome harms heart blood vessels

  The team is testing whether common diabetes drugs can help blood vessels grow and protect the heart in people with metabolic syndrome and diabetes by studying a pig model that mimics patients.

  NIH research Rhode Island Hospital · Providence, United States · NIH-11097242

• Exploring the use of a protein to improve heart recovery after injury.

  This study is looking at how a small protein called ubiquitin might help the heart heal better after it's been damaged from not getting enough blood, like during a heart attack, by reducing inflammation and scarring.

  NIH research James H Quillen VA Medical Center · Mountain Home, United States · NIH-11092679

• Investigating how a mitochondrial protein protects the heart during injury from blood flow restoration

  This study is looking at a protein called LonP1 that might help protect heart cells from damage when blood flow returns after a heart attack, with the hope of finding new treatments to help your heart heal better.

  NIH research West Virginia University · Morgantown, United States · NIH-11077313

• Improving heart function by targeting specific proteins in blood vessels

  This study is looking at how specific proteins can help improve blood flow and heart function for people with narrowed arteries, aiming to find new ways to support heart healing and recovery after heart attacks.

  NIH research Boston Children's Hospital · Boston, United States · NIH-10944711

• Using engineered heart tissues to improve recovery after heart attacks

  This study is exploring a new way to help people recover from heart attacks by creating tiny heart tissues made from human cells that can be transplanted into damaged hearts to improve their function and healing.

  NIH research Clemson University · Clemson, United States · NIH-10897061

• Investigating new lipid molecules in heart disease

  This study is looking at how certain fats in the body might affect heart health when blood flow to the heart is reduced, which can happen in conditions like ischemic cardiomyopathy, and it's for anyone interested in understanding more about heart problems and potential new treatments.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-10868621

• Using light exposure to protect the heart during surgery

  This study is looking at how using bright light can help protect the heart during surgery by boosting a special protein, and it's aimed at finding new ways to keep patients safe while they undergo heart procedures.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10705355

• Creating a new drug to treat heart damage after a heart attack

  This study is testing a new medication that aims to help people who have had a heart attack by reducing heart damage when blood flow is restored, and it could lead to better recovery and lower chances of heart failure.

  NIH research Dupage Medical Technology, INC. · Chicago, UNITED STATES · NIH-10491205

Related topics

Quick answers

How many Myocardial Ischemia clinical trials are recruiting right now?

26, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 18 countries. The most sites are in Spain (4 trials), United States (4 trials), Italy (4 trials), France (3 trials), United Kingdom (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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