Using a smartphone device to record 12-lead ECGs for heart attack diagnosis

Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II (STLEUISII)

Not applicable Interventional AliveCor · NCT06271577

This study is testing a smartphone device that records heart activity to see if it can help doctors quickly diagnose heart attacks in adults who come to the emergency room with chest pain.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1000 (estimated)
Ages18 Years and up
SexAll
SponsorAliveCor Industry-sponsored
Locations4 sites (Rochester, Minnesota and 3 other locations)
Trial IDNCT06271577 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of the AliveCor 12-lead ECG System, which can record multiple leads of ECG simultaneously, in diagnosing ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI). Participants will be adults presenting with chest pain at emergency departments, where the device's performance will be compared to standard ECG methods. The study aims to validate the accuracy of this innovative technology in a clinical setting, potentially improving rapid diagnosis and treatment of heart conditions.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old who present with symptoms of chest pain at participating emergency departments.

Not a fit: Patients who are unable or unwilling to provide informed consent or have conditions that may increase their risk during the trial may not benefit from this study.

Why it matters

Potential benefit: If successful, this technology could enable faster and more accurate diagnosis of heart attacks, leading to timely treatment and improved patient outcomes.

How similar studies have performed: Previous studies, such as the ST LEUIS study, have shown success in validating similar ECG devices for diagnosing myocardial infarctions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or female \> 18 years of age.
* Ability to understand and sign a written informed consent form, which must be obtained prior to initiation of any study procedures.
* Symptoms of chest pain upon presentation at the Emergency Department of the participating institution.

Exclusion Criteria:

* Inability or refusal of the patient and/or the patient's legally acceptable representative to provide written informed consent for any reason.
* Other conditions that in the opinion of the Lead Investigator may increase risk to the subject and/or compromise the quality of the clinical trial.

Where this trial is running

Rochester, Minnesota and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Myocardial InfarctionIschemiaMyocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesHeart AttackHeart Failure
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.