Improving diagnosis of anomalous coronary arteries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to enhance the diagnosis and evaluation of anomalous aortic origin of the coronary arteries (AAOCA) using advanced technologies such as machine learning and artificial intelligence. A web-based platform will be developed to process anonymized Computed Tomography Angiography (CTA) images, allowing for automatic segmentation and identification of anomalous coronary origins. The platform will integrate anatomical measurements with clinical data to assess the risk of sudden cardiac death and major ischemic events. This innovative approach seeks to provide a more accurate and personalized risk stratification for patients with AAOCA.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult and pediatric patients (age \> 6 years) with anomalous coronary origin from the aorta (AAOCA).
* Patients in spontaneous sinus rhythm.
* Signed informed consent.

Exclusion Criteria:

* Patients with acute and chronic inflammatory conditions such as chronic liver disease, chronic kidney failure (creatinine \> 1.5 mg/dl), and thyroid disorders.
* Patients with arrhythmias, absence of sinus rhythm.
* Contraindications to autonomic testing.
* Patients with a known allergy to materials in recording devices.
* Female patients who are pregnant.

Where it's running

• IRCCS Policlinico San Donato
  San Donato Milanese, Italia, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.