Registry to optimize management and outcomes for patients with acute myocardial infarction
OPTIMISER Registry - A Prospective Cohort Study to Describe the OPTIMal Management and Outcomes of PatIents PreSEnting With Acute MyocaRdial Infarction
This study is looking at how well different treatments work for patients who have had a heart attack and received a specific procedure called PCI, to see what helps them recover better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Luzerner Kantonsspital Academic / other |
| Locations | 1 site (Lucerne) |
| Trial ID | NCT04988672 on ClinicalTrials.gov |
What this trial studies
The OPTIMISER Registry aims to collect both baseline and clinical data from patients presenting with acute myocardial infarction (AMI) who are treated with percutaneous coronary intervention (PCI). This observational study will analyze procedural success and clinical outcomes, comparing results across different clinical subgroups. It will assess various procedural outcomes, long-term clinical outcomes, and the impact of different devices and strategies used during PCI. Additionally, the study will evaluate predictors for stent implantation failure and the effects of antithrombotic regimens on patient outcomes.
Who should consider this trial
Good fit: Ideal candidates include individuals over 18 years old who are newly diagnosed with AMI or have been diagnosed within the last five years.
Not a fit: Patients who are unwilling or unable to provide informed consent or those with conditions unrelated to acute coronary syndrome will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies and outcomes for patients experiencing acute myocardial infarction.
How similar studies have performed: Other studies have shown success in optimizing treatment strategies for AMI, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subject \>18 years of age * Individuals who are newly diagnosed with AMI or have been diagnosed with AMI (STEMI or NSTEMI) within the last 5 years (since 2016). * Subjects must be willing to sign a patient informed consent (PIC) OR a patient ́s relative/ proxy are willing to provide PIC or patients have signed the General Consent (GK). Exclusion Criteria: * Patient unwilling or unable to provide informed consent * Patients with no ACS/AMI (e.g. Takotsubo cardiomyopathy, acute heart failure not related to AMI)
Where this trial is running
Lucerne
- Luzerner Heart Centre — Lucerne, Switzerland (Recruiting)
Study contacts
- Principal investigator: Florim Cuculi, M.D. — Luzerner Kantonsspital
- Study coordinator: Florim Cuculi, M.D.
- Email: florim.cuculi@luks.ch
- Phone: +41412052134
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.