Clinical trial Recruiting at 1 site Observational Ages 18 and up

Registry to optimize management and outcomes for patients with acute myocardial infarction

Official title: OPTIMISER Registry - A Prospective Cohort Study to Describe the OPTIMal Management and Outcomes of PatIents PreSEnting With Acute MyocaRdial Infarction

Run by Luzerner Kantonsspital · NCT04988672 · Data updated 2026-11-12

This study is looking at how well different treatments work for patients who have had a heart attack and received a specific procedure called PCI, to see what helps them recover better.

More Myocardial Infarction trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment4000 (estimated)
SponsorLuzerner Kantonsspital
Academic / other
Locations1 site (Lucerne)
StatusRecruiting
StartedJanuary 1, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2030
Registry record updatedOctober 6, 2023
Trial IDNCT04988672 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals over 18 years old who are newly diagnosed with AMI or have been diagnosed within the last five years.

Probably not a fit

Patients who are unwilling or unable to provide informed consent or those with conditions unrelated to acute coronary syndrome will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The OPTIMISER Registry aims to collect both baseline and clinical data from patients presenting with acute myocardial infarction (AMI) who are treated with percutaneous coronary intervention (PCI). This observational study will analyze procedural success and clinical outcomes, comparing results across different clinical subgroups. It will assess various procedural outcomes, long-term clinical outcomes, and the impact of different devices and strategies used during PCI. Additionally, the study will evaluate predictors for stent implantation failure and the effects of antithrombotic regimens on patient outcomes.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies and outcomes for patients experiencing acute myocardial infarction.

How similar studies have gone: Other studies have shown success in optimizing treatment strategies for AMI, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subject \>18 years of age
* Individuals who are newly diagnosed with AMI or have been diagnosed with AMI (STEMI or NSTEMI) within the last 5 years (since 2016).
* Subjects must be willing to sign a patient informed consent (PIC) OR a patient ́s relative/ proxy are willing to provide PIC or patients have signed the General Consent (GK).

Exclusion Criteria:

* Patient unwilling or unable to provide informed consent
* Patients with no ACS/AMI (e.g. Takotsubo cardiomyopathy, acute heart failure not related to AMI)

Where it's running

  • Luzerner Heart Centre
    Lucerne, Switzerland
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.