Condition

Coronary Disease clinical trials and research

• 24Clinical trials
• 3NIH research projects
• 1New in 30 days
• 17Countries

Newest Coronary Disease clinical trials

All recruiting trials (24)

• Tailored digital support to cut sedentary time in long-term cardiac rehab

  In adults in a long-term cardiac rehabilitation program, this study tests whether a personalized behavioural program with digital tools can reduce daily sitting time.

  Recruiting University of Lisbon · Lisbon, Lisbon District · NCT07910812

• Predicting how coronary artery disease progresses in adults 45 and younger

  This project will try to build prediction models using coronary CT scans and health data from people aged 18–45 to see who is more likely to have plaque get worse over time.

  Recruiting Fu Wai Hospital, Beijing, China · Beijing · NCT07316452

• Freesolve resorbable magnesium scaffold vs. Xience stent for up to two new heart artery lesions

  This trial tests whether the Freesolve resorbable magnesium scaffold works as well as the Xience drug-eluting stent for treating up to two new coronary artery lesions in adults.

  Recruiting at 3 sites Teleflex · Washington D.C., District of Columbia and 2 other locations · NCT07258290

• Italian Cardiac Rehabilitation Registry for Coronary Disease and Heart Failure

  This registry collects real-world information to see how cardiac rehabilitation programs work for adults recovering from coronary disease or heart failure across Italy.

  Recruiting Fondazione Don Carlo Gnocchi ETS · Milan · NCT07094737

• Orbital atherectomy versus standard balloon strategy for calcified coronary bifurcation lesions

  This study tests whether using orbital atherectomy before stenting helps adults with moderately or severely calcified coronary bifurcation lesions get better stent results than the standard balloon-first approach.

  Recruiting at 9 sites Fundación EPIC · Alicante and 8 other locations · NCT06736899

• Healthy Nordic diet's effects on heart disease

  This study is testing if following a Healthy Nordic diet can help people with coronary heart disease improve their heart health over 18 months.

  Recruiting Uppsala University · Uppsala · NCT06701968

• Comparing heart imaging techniques for coronary artery disease

  This study is testing if a new heart imaging method can better identify problems in patients suspected of having coronary artery disease compared to a traditional imaging technique.

  Recruiting Semmelweis University · Budapest, Budapest · NCT06670768

• Measuring treatment compliance for sleep apnea in heart disease patients

  This study tests how well heart disease patients with sleep apnea stick to using two different treatments, a CPAP machine and a mouthpiece, to see which one they find easier to use.

  Recruiting University Hospital, Montpellier · Montpellier · NCT06568159

• Single versus dual antiplatelet therapy after drug-coated balloon angioplasty in elderly or high-bleeding-risk patients

  This study tests whether taking one antiplatelet medicine is as safe and causes less bleeding than taking two medicines for people aged 75 or older, or adults at high bleeding risk, after drug-coated balloon angioplasty for coronary artery disease.

  Recruiting Fondazione Ricerca e Innovazione Cardiovascolare ETS · Milan, MI · NCT06535568

• Evaluating new methods for assessing coronary artery disease after procedures

  This study is testing a new way to check for coronary artery disease in patients with multiple blocked arteries to see if it works better than the usual method after they have heart procedures.

  Recruiting at 4 sites Fundación EPIC · Alicante and 3 other locations · NCT06273293

• Using a special stent to treat coronary artery perforations

  This study tests a special stent to see if it can help patients with sudden tears in their coronary arteries feel better and avoid serious problems.

  Recruiting Methodist Health System · Dallas, Texas · NCT06223633

• Comparing stress echocardiography and CT coronary angiography for chronic coronary syndrome

  This study is testing whether a combination of stress echocardiography and carotid ultrasound works better than regular CT scans for diagnosing heart problems in adults with chronic coronary syndrome.

  Recruiting London North West Healthcare NHS Trust · Harrow, Middx · NCT06185530

• Comparing two methods for diagnosing heart conditions in patients with non-ST elevation acute coronary syndrome

  This study is testing if a non-invasive heart scan can safely and effectively diagnose heart conditions in patients with certain types of heart attacks, compared to the traditional invasive method.

  Recruiting at 6 sites Copenhagen University Hospital, Rigshospitalet · Copenhagen, Hellerup and 5 other locations · NCT06101862

• Registry to track management and outcomes of patients with complex coronary artery disease

  This study is tracking how well different treatments for complex coronary artery disease work in patients who have had procedures like stents or bypass surgery.

  Recruiting Luzerner Kantonsspital · Lucerne, Canton of Lucerne · NCT06075602

• Evaluating a robotic system for coronary angioplasty procedures

  This study is testing a new robotic system to see if it can safely help doctors perform heart procedures for patients with blocked arteries.

  Recruiting at 5 sites Robocath · Antwerp and 7 other locations · NCT05853419

• Comparing two methods for heart artery treatment in patients with coronary disease

  This study is testing which method of guiding heart artery treatment works better for patients with coronary artery disease by comparing two different approaches during their procedures.

  Recruiting at 12 sites Asan Medical Center · Anyang and 16 other locations · NCT05529459

• Comparing two methods for treating severely calcified coronary lesions

  This study tests two different devices to see which one works better for preparing tough, calcified heart arteries before putting in a stent for people with coronary artery disease.

  Recruiting Luzerner Kantonsspital · Lucerne · NCT05346068

• Evaluating the effectiveness and safety of Synergy XD and Megatron stents

  This study is testing how well and safely the Synergy XD and Megatron stents work for people with coronary artery disease compared to other stents in real-life situations.

  Recruiting at 19 sites Asan Medical Center · Anyang and 22 other locations · NCT05044273

• Registry to evaluate outcomes of coronary artery disease patients treated with specific balloon catheters

  This study looks at how well certain drug-coated balloons work for patients with coronary artery disease who have had a specific heart procedure, to see how they help with recovery and overall health.

  Recruiting Luzerner Kantonsspital · Lucerne, Canton of Lucerne · NCT04988685

• Long-term remote ischemic preconditioning to improve heart blood flow and outcomes after CABG

  This trial tries whether repeated arm‑cuff blood‑flow interruptions (remote ischemic preconditioning) can improve heart blood flow and outcomes for people having CABG.

  Recruiting Henan Institute of Cardiovascular Epidemiology · Zhengzhou, Henan · NCT04779008

• Evaluating the effectiveness of the DESyne X2 coronary stent in clinical practice

  This study is testing how well the DESyne X2 stent works for people with blocked arteries who are getting a heart procedure.

  Recruiting at 2 sites Asan Medical Center · Incheon and 5 other locations · NCT03588481

• Evaluating heart imaging techniques for coronary disease treatment

  This study is testing whether using a specific heart imaging technique called computed tomography perfusion can help people with coronary artery disease get better treatment results compared to another method called fractional flow reserve.

  Recruiting Asan Medical Center · Seoul, Songpa-Gu and 6 other locations · NCT02208388

• Evaluating new radiation techniques for heart imaging

  This study is testing new heart imaging techniques that use less radiation to see if they can still provide accurate results for diagnosing coronary disease.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT01621594

• Survey of patients with acute coronary syndromes

  This study is looking to gather information from patients with heart problems like unstable angina and heart attacks in Eastern Europe to see how they are treated and how they do over time.

  Recruiting University of Bologna · Bologna, Emilia-Romagna · NCT01218776

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How the protective gene TCF21 helps arteries resist heart disease

  This research looks at how a protective gene called TCF21 changes artery wall cells in ways that may lower the risk of coronary artery disease.

  NIH research Stanford University · Stanford, United States · NIH-11243486

• Understanding how blood vessel calcification is linked to heart disease risk

  This study is looking at how certain cells in your blood vessels change and contribute to heart disease, with the hope of finding new ways to prevent or treat conditions like coronary artery disease.

  NIH research Stanford University · Stanford, United States · NIH-11082325

• Investigating how mindfulness affects inflammation in heart disease

  This study is looking at how practicing mindfulness can help reduce inflammation and improve heart health in people with stable coronary disease by seeing how stress affects the brain and body.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11010415

Related topics

Quick answers

How many Coronary Disease clinical trials are recruiting right now?

24, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 17 countries. The most sites are in South Korea (4 trials), Italy (4 trials), Switzerland (3 trials), United States (3 trials), China (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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