Detecting heart muscle injury during below-knee leg surgery with peripheral nerve block

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study that measures high‑sensitive troponin I levels before surgery, during the operation, and at 24 and 48 hours after below‑knee lower extremity procedures performed with peripheral nerve blocks. Clinical and anesthetic details (type and dose of local anesthetic, intraoperative blood pressure, heart rate changes, inotrope use, fluids, urine output, and operation time) will be recorded to look for factors associated with troponin changes. The primary focus is whether perioperative troponin elevations indicate myocardial injury in this surgical setting; secondary analyses will explore which perioperative parameters correlate with troponin rise. All participants will have routine preoperative labs and hs‑troponin I measured as part of the monitoring protocol.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over 18 years of age
* Patients undergoing below-knee lower extremity surgery
* Patients with ASA classifications I, II, III, and IV
* Patients who have consented before the procedure
* Patients who are literate and able to give consent

Exclusion Criteria:

* Patients in whom regional anesthesia is contraindicated
* Patients who refuse to participate in the study

Where it's running

• Ankara Bilkent City Hospital
  Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Harun Zengin — harunzengin71@gmail.com
• Study coordinator: Harun Zengin
• Email: harunzengin71@gmail.com
• Phone: 05422358195

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Peripheral nerve decompression plus nerve stimulation for painful diabetic neuropathy

  This study looks at whether combining nerve decompression with nerve stimulation can help reduce pain in people with painful diabetic neuropathy.

  Recruiting at 4 sites Qilu Hospital of Shandong University · Jinan, Shandong and 3 other locations · NCT07911410

• Cardio-Metabolic Clinic care for adults with type 2 diabetes and cardiovascular disease

  This trial tests whether a specialized Cardio-Metabolic Clinic can improve heart function and overall health for adults with type 2 diabetes and cardiovascular disease compared with usual care.

  Recruiting Odense University Hospital · Svendborg · NCT07878325

• Pediatric Cardiac Oxygenation Monitoring During Open-Heart Surgery

  This study tests whether the SpectroCor Tissue Oxygenation Monitor and its Sensor can track heart tissue oxygen levels in children undergoing open-heart surgery.

  Recruiting Spectrocor · Helsinki, Uusimaa · NCT07785141

• 4-electrode tablet ECG vs standard 12-lead ECG: see which is faster and clearer

  This study tests whether the 4-electrode DigitalCardio tablet ECG can record a full ECG faster and with comparable trace quality to a standard 12-lead ECG in adults with heart conditions.

  Recruiting Clinique Bizet · Paris and 1 other locations · NCT07732283

• Magnetocardiography in people with chest pain and non-obstructive heart arteries

  This study uses magnetocardiography to see if it can help identify non-obstructive myocardial ischemia in adults with acute chest pain.

  Recruiting Qilu Hospital of Shandong University · Jinan, Shandong · NCT07657546

• AI-assisted cardiac CT to predict coronary artery disease risk

  This project will try using AI-enhanced heart CT scans to better predict future coronary events in adults who are already getting a clinical cardiac CT.

  Recruiting University of Galway · Galway · NCT07577609

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.